Global Blau syndrome Market – Industry Trends and Forecast to 2030

Blau syndrome Market Analysis and Size

Several advancements in the health care industry of blau syndrome will impact in launching new product by the several manufacturers into the market, improving its demand along with availability of off-label drugs. Furthermore, every day changing technologies also puts a hindrance for physicians to perform the numerous kinds of genetic tests. Presently, numerous research studies are taking place which is projected to create a competitive advantage for manufacturers to develop advanced and innovative blau syndrome drugs which is projected to provide several other opportunities in the blau syndrome market.

 Data Bridge Market Research analyses a growth rate in the blau syndrome market in the forecast period 2023-2030. The expected CAGR of blau syndrome market is tend to be around 12.4% in the mentioned forecast period. The market is valued at USD 7.13 million in 2022, and it would grow upto USD 18.16 million by 2030. In addition to the market insights such as market value, growth rate, market segments, geographical coverage, market players, and market scenario, the market report curated by the Data Bridge Market Research team also includes in-depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.

Report Scope and Market Segmentation

Market Definition

Blau Syndrome typically presents in childhood with the triad of granulomatous dermatitis, arthritis, and uveitis. This syndrome is also termed as familial juvenile systemic granulomatosis. Even though a skin rash is not necessarily a ubiquitous feature of Blau syndrome, it is mostly the first sign of disease if it is available. In majority of the cases, a normal rash appears within the first year of life and presents as discrete, erythematous papules. In this condition, the most common feature which is arthritis, tends to rise between the ages of 2 to 4 years.

Blau Syndrome Market Dynamics

Drivers

• Increasing Diagnostic Procedures

There have been increasing diagnostic procedures available which boosts the market growth. Optical coherence tomography (OCT) may be used to depict the extent of ocular disease. Skin or synovial biopsy may be used that will reveal noncaseating granulomas. Out of these two options, skin biopsy is less invasive and has showed higher accuracy. Furthermore, next generation sequencing may be used to test for causative NOD2 mutations, which will confirm the diagnosis. X-rays show dysplastic changes, such as camptodactyly, carpal dysplasia, abnormal ulna and second metacarpal bone shape, abnormal distal radial epiphysis, short ulna. Complete blood count (CBC), C-reactive protein (CRP), serum angiotensin-converting enzyme (ACE), erythrocyte sedimentation rate (ESR), antinuclear antibody (ANA), anti-neutrophilic cytoplasmic antibody (ANCA), anti-dsDNA antibody, Lyme disease serology, rheumatoid factor (RF),  RPR/VDRL, human leukocyte antigen (HLA) testing, tuberculin skin test, pathergy skin test are the types of tests that can be performed.

Opportunities

• Growing Treatment Options

Treatment options such as corticosteroids also have utility during quiescent periods. The prolonged need for corticosteroids, along with the frequency of refractory symptoms, signifies the use of immunosuppressants such as mycophenolate mofetil, methotrexate, or azathioprine. For this reason, the wide use of monoclonal antibodies to target these cytokines has become helpful; though, variable degrees of efficacy have been witnessed in the literature. It is difficult to determine the true therapeutic benefit of these agents due to contrasting results and the relatively scarce amount of data available. Though medical management is the keystone of treatment for patients with Blau syndrome, operative intervention is also used in certain scenarios. There are many ocular diseases, wherein many inflammatory sequelae should be addressed surgically. Patients may opt to undergo joint fusion procedures because of severe, unrelenting arthritis. Thus, this boosts the market growth.

• Increasing Product Launches and Developments

There has been rising number of product launches and developments that lead to the growth of the market. For instance, in April 2018, Swedish Orphan Biovitrum AB (publ) approval for Kineret which is a monoclonal antibody used for treatment of rare disease. This product approval aided the company to improve its products sales. Furthermore, in October 2016, Teva Pharmaceutical Industries Ltd. has completed the acquisition of Allergan’s Anda Inc which is the fourth largest distributor of generics medicines in the U.S. and majority of the Blau syndrome drugs such as methotrexate, azathioprine are widely available as generic drugs, hence this acquisition supported the company to enlarge its generic product portfolio for treatment of Blau syndrome. Thus, this boosts the market growth.

Restraints/Challenges

• Unavailability of skilled professionals

The wide unavailability of qualified professionals who cannot treat the patients with appropriate treatments could restrict the market growth during the forecast period 2023-2030.

• High Cost of Treatment

The increasing expenditure related with medications hinder the market growth. These inhibitors cost high and people in the developing and underdeveloped countries can lead to the under treatment of numerous patients. This hinders the market growth.

This blau syndrome market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the blau syndrome market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

Global Blau Syndrome Market Scope

The blau syndrome market is segmented on the basis of therapeutic areas, route of administration, end-users and distribution channel. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Therapeutic Areas

• Skin Rash
• Inflammation

Route of Administration

• Oral
• Parenteral
• Topical
• Others

End User

• Hospitals
• Homecare
• Specialty Clinics
• Others

Distribution Channel

• Hospital Pharmacy
• Online Pharmacy
• Retail Pharmacy

Blau Syndrome Market Regional Analysis/Insights

The blau syndrome market is analyzed and market size insights and trends are provided by therapeutic areas, route of administration, end-users and distribution channel as referenced above.

The major countries covered in the blau syndrome market report are the U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America has been witnessing a positive growth for blau syndrome market throughout the forecasted period because of high healthcare and research & development expenditure. Also, the growing prevalence of autoimmune inflammatory diseases and increasing demand for all types of treatment boost the growth.

Asia-Pacific dominates the market because of the increased generic market players. And also the growing prevalence of rare genetic disorders boost the growth in this region.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.   

Competitive Landscape and Global Blau Syndrome Market Share Analysis

The blau syndrome market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to blau syndrome market

Key players operating in the blau syndrome market include:

• Abbvie, Inc (U.S.)
• Novartis AG (Switzerland)
• Teva Pharmaceutical Industries Ltd (Israel)
• Pfizer Inc. (U.S.)
• Amgen Inc. (U.S.)
• Janssen Global Services, LLC (U.S.)
• F. Hoffmann-La Roche Ltd. (Switzerland)
• Mylan N.V. (U.S.)
• Hikma Pharmaceuticals PLC (U.K.)
• Fulgent Genetics (U.S.)
• Invitae Corporation (U.S.)
• Swedish Orphan Biovitrum AB (Sweden)
• Alkem Labs Ltd (India)
• Accord Healthcare (U.K.)
• Zydus Group (India)
• Amneal Pharmaceutical Inc. (U.K.)
• CENTOGENE N.V. (Germany)

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