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Artificially Creating Genetic Switches for Yeast:

  • Uncategorized
  • Jul 09, 2021

A team of researchers have successfully developed a flexible yet, a simple method through which we can artificially produce genetic switches for yeast. The process and functioning of genetic switches is to make few functions to theatrically happen in the process in the eukaryotic organisms. Genetic switches are made to function in order to artificially generate brand new functions present in an organism. A platform is established by the researchers for creating genetic switches that eventually applied for the development of highly sophisticated and artificially controlled yeast cells which is helpful in the production of large quantities of valuable compounds. These compounds are helpful in making many food items and other things made in daily life. The market of yeast is growing rapidly which positively impacts the food market as well. Genetic switches have a particular task and that is, performing the gene expression. These networks are basically a gene regulatory network and a cut off threshold can be set up to maintain the platform.

Genetic switches are necessary to artificially create new functions in an organism. These switches control the amount of proteins that are produced by a gene and when it is produced in eukaryotic organisms in particular, the development of genetic switches gets delayed and the number of genes that can be controlled simultaneously is severely limited. Selection platform can also be developed on which the limit threshold can be set. This enabled them to develop highly functional artificial genetic switches for yeast that can be made easily and flexibly. The platform developed is expected to have a wide range of uses in situations where precise control of expression levels and large number of genes is required. It also includes optimizing the balance of expression of metabolic enzymes in building cells to be useful in achieving results substances that have complexes intracellular metabolism.

The number and type of genes that an organism possesses do not determine its life’s function. The timing and quantity of proteins produced by a gene (i.e. gene expression) are other factors that are known to result in significant alterations. In the field of synthetic biology, recent advances have made it possible to generate many novel cell functions by artificially controlling the expression of certain genes. Genetic switches are necessary in order to control the rate and timing of gene expression.