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Corporación Biofarmacéutica impulsará el desarrollo de candidatos a fármacos oncológicos LADR (liberación de fármacos activada por enlazador) de potencia ultraalta

Hoy en día, la industria de la salud se centra más en medicamentos especializados para brindar un mejor tratamiento a los pacientes. Los medicamentos de alta potencia suelen contener ingredientes farmacéuticos activos de alta potencia (HPAPI), que suelen utilizar pequeñas moléculas para el análisis de enfermedades como el cáncer, trastornos respiratorios y desequilibrios hormonales. Estos medicamentos suelen tener efectos secundarios mínimos, ya que están diseñados específicamente para una enfermedad específica, lo que contribuye a una recuperación más rápida del paciente. Son muy adecuados para tratar enfermedades potencialmente mortales. Hoy en día, tanto fabricantes como desarrolladores utilizan nuevas tecnologías y soluciones para el desarrollo de nuevos fármacos muy eficaces. Recientemente, CytRx Corporation anunció el lanzamiento de su nueva filial, Centurion BioPharma Corporation, que se centrará principalmente en el desarrollo de fármacos oncológicos candidatos LADR (liberación de fármacos activada por enlazadores) de ultraalta potencia. Su oficina administrativa se encuentra en Los Ángeles, California. LADR-7, LADR-8, LADR-9 y LADR-10 son los candidatos LADR que están siendo desarrollados por el equipo de descubrimiento en laboratorios alemanes y tienen la capacidad de progresar a estudios que permitan la formación de nuevos fármacos en investigación. Estos nuevos candidatos se desarrollan utilizando la tecnología LADR de la compañía. También puede controlar la ubicación del tumor mediante la unión molecular del compuesto farmacológico al torrente sanguíneo del cuerpo. También puede disminuir la toxicidad del sistema. Esta nueva plataforma es una combinación de la química de enlace de la compañía con la tecnología de albúmina para que puedan transportar agentes de alta potencia a los tumores. Según Eric L. Curtis, director ejecutivo y presidente de Centurion BioPharma Corporation, la creación de esta nueva subsidiaria será muy útil, ya que fortalecerá las pertenencias farmacéuticas de CytRx y, con el avance en la línea de fármacos candidatos LADR de ultra alta potencia con unión a la albúmina, tendrán éxito en atraer a un gran número de licenciatarios. La tecnología LADR de Centurion Biopharma consiste en una cartera de nuevas moléculas enlazadoras que pueden circular por la albúmina y unirse a diferentes cargas útiles anticancerígenas. Estos compuestos presentan una gran actividad antitumoral en diversos tipos de cáncer, como el de cuello uterino, ovario, melanoma, riñón, pulmón y mama. La compañía busca crear nuevas moléculas combinando cargas útiles citotóxicas de alta potencia con enlazadores ajustables.

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