Growing Demand for Virus Titration and Purification of Antibodies and Increased Demand of Research in Drug Discovery and Biological Researches is Expected to Drive the Growth of the Global Prepacked Chromatography Columns Market in the forecast period of 2019 to 2026

DRIVERS:

Growing demand for virus titration and purification of antibodies

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The health issues are increasing worldwide and every individual is suffering from some or another disease which requires the biological fluid testing. This requires purification of antibodies which implies diagnostic manufacturing and therapeutic drug development to create infinite numbers of specialized combinations between immunoglobulins and its fragments along with a number of proteins. Viruses in purified forms find their application in vaccines and prove to be of great potential in gene therapy vectors. Bacterial viruses, also known as bacteriophages are the most prominent viruses that treat bacterial infections and are being used as an alternative in the laboratories against the antibiotics.

Thus these different kinds of health related issues increase the demand for antibody purification and virus titration techniques driving the prepacked chromatography columns market globally.

  • In August 2018, Bio-Rad Laboratories, Inc. announced the launch of two chromatography samples for protein purification namely CHT Ceramic Hydroxyapatite Mixed-Mode Media and Nuvia HP-Q Anion Exchange Resin formulated as per the customer needs. Both had their own benefits and were applicable in providing monoclonal and polyclonal antibodies and various other proteins. They were mainly launched for a more robust resin with superior performance.

Increased demand of research in drug discovery and biological researches

Research and development towards creating new innovative pharmaceuticals in the pharma industry is becoming important due to the threat of patent expiration of the branded products and entry of generic competitors in the future market. Thus new discoveries of medicines and various types of pharmaceuticals is taking place every day in the laboratories. A drug discovery lasts many years and requires proper testing at each particular level of its production.The high demand for discovery of pharmaceuticals is ultimately increasing the demand for prepacked columns in the labs.

  • In February, Merck is investing USD 70 million for the expansion of the research and development centre in Billerica, Massachusetts. The centre will be committed in innovation & development in the field of oncology, immuno-oncology and immunology. Merck is a well-known name in life science and this expansion is a testament to the state’s global leadership.

Increased demand of packaged drinks to support prepacked chromatography columns

The fast paced lives of the working employee in the present scenario increase the demand of packaged drinks in the market at a very high rate. The packaged drinks mainly are composed of compounds that can sometimes prove fatal to health if not properly tested and purified before manufacturing. This major factor increases the demand for prepacked chromatography columns in the labs where these packaged drinks are tested before manufacturing them. The main function of column chromatography in packaged drinks lies in the detection of synthetic food dyes in soft drinks in the form of natural colours.

  • In March, Waters Corporation launched a new product VICAM food and agricultural laboratories. It will quickly isolate and purify BPA for analysis from 0.1 to 50 parts per billion in as little as ten minutes total preparation time. The product will serve analytical excellence in giving empower to food manufacturers and regulators to safeguard human health.

RESTRAINTS

Crunch of large sized columns globally

The extraction efficiency of the compounds is highly dependent on the shape and size of the columns being used in the laboratories. The shape of the column affects the absorbance and selectivity of the compound. Therefore, selection of the size of the column should be done carefully in order to avoid affecting the result.

To obtain a high quality end user product this involves complex procedures of sample preparation in biopharmaceuticals laboratories where large sized columns are required. Thus crunch of large sized columns in the laboratories acts as a restraint to the market.

High cost of resins

The cost of resin is decided by the type of resin, realistic size of the columns and throughput of the single unit operation being used in the particular chromatography technique. The volume of resin to be used is pre decided. If the volume is increased, the cost of the whole product is raised at a high rate.

The rising demand of the natural resins which are used in size exclusions and paper chromatography techniques is rising at a higher rate due to accurate analytical results. But increasing cos of resins is declining the demand of these resins which acts as a restrain to the market.

OPPORTUNITIES

Multiple use prepacked chromatography columns for packaged drinks

Everyday millions of diagnostic tests are performed worldwide. Therefore, the prepacked column products are also used in large number which leads to the high demand of the product. One such method that can be adopted is the multiple use of a single prepacked column for a variety of applications. Different colours can be used in the column in order to mark the kind of chemical present in the beverage.

This multifunctional operation would have several advantages to both the markets of column chromatography and packaged drinks. There could be better use of columns in an efficient way making faster production of healthy packaged drinks through multilevel testing of products.

Expansion in lightweight products for ease of handling

Generally the columns required for normal processing of columns chromatography procedure varies according to the type of experiments performed. The compact lightweight columns provide a lot of empty space for the experiments within the working environment leaving the room spacious for a safe operational performance.

The prepacked chromatography columns market should expand themselves towards the lightweight columns for ease handling of experiments and chemical compounds in the laboratories as it sometimes becomes difficult for the specialized workers to perform certain experiments which includes columns packed with resins.

CHALLENGES

Extensive time require for the production of customized columns

Customized columns are off-the-shelf product which offers custom solutions as per the requirements including a variety of packing, fittings and options for quality control testing of samples. Extensive time is required in order to prepare such customized columns as they involve complex procedures and quality control testing of samples.

Customized columns are mainly user defined and require being proper and efficient accordingly. To overcome such challenges the prepacked columns sometimes face difficulties in order to meet the demands of the researchers.

Limited availability of qualified technicians

The diagnostic labs, research labs and other labs that perform sample preparation and protein purification should be maintained by qualified technicians who should have thorough knowledge regarding the chromatography techniques involved. Prepacked column chromatography technique is highly dependent on the skilled technicians.

Lack of skilled labors will challenge the market to grow because unskilled labors are prone to make mistake, which would end up in giving inaccurate results.

Market Trends:

Global   prepacked chromatography columns market is segmented into four notable segments which are product type, techniques, application and end-user.

  • On the basis of product type, the market is segmented into >1 Litre Column, 100-1000ML Column and 1-100ML Column. In 2019, >1 Litre Column segment is expected to dominate the global prepacked chromatography columns market with 53.37% market share and also growing at highest CAGR of 10.8% in the forecast period 2019 to 2026.
  • On the basis of Technique, the market is segmented into ion exchange chromatography, hydrophobic stationary phase chromatography, multimodal chromatography, affinity chromatography and gel filtration chromatography. In 2019, ion exchange chromatography segment is expected to dominate the global prepacked chromatography columns market with 32.94% market share and also expected to be growing at the highest CAGR of 11.1% in the forecast period 2019 to 2026.
  • On the basis of application, the market is segmented into sample preparation, resin screening, protein purification, anion and cation exchange, affinity chromatography and desalting. In 2019, sample preparation segment is expected to dominate the global prepacked chromatography columns market with 32.22% market share and also expected to be growing at highest CAGR of 11.1% in the forecast period 2019 to 2026.
  • On the basis of end-user, the market is segmented into pharmaceutical biotechnology, nutraceuticals, food & beverages, analytical laboratories, agriculture & environment and academics & research. In 2019, pharmaceutical biotechnology segment is expected to dominate the global prepacked chromatography columns market with 29.54% market share and is expected to be growing at highest CAGR of 11.1% in the forecast period 2019 to 2026.

Major Players: Global Prepacked Chromatography Columns Market

Some of the major players operating in this market are Tosoh Corporation, Thermo Fisher Scientific Inc., Cole-Parmer Instrument Company, LLC. , sunresin, Purolite, Shimadzu Corporation, YMC Europe GMBH, F. Hoffmann-La Roche Ltd, Repligen Corporation, Bio-Rad Laboratories, Inc., Agilent Technologies, Inc., WATERS, Phenomenex Inc., GENERAL ELECTRIC, Merck & Co., Inc., Danaher, Halma plc. and others.