- In April 2025, Kyowa Hakko Bio Co., Ltd., a global leader in amino acid production, launched a new pharmaceutical-grade L-citrulline ingredient for clinical and therapeutic use. This highly purified formulation is tailored for cardiovascular and metabolic health applications, supporting the company’s expansion into regulated medical markets. The development reinforces Kyowa Hakko’s commitment to innovation and its leadership in the amino acid segment
- In March 2025, NutraBio Labs introduced a new vegan-certified, non-GMO L-citrulline powder under its sports nutrition portfolio. Designed for pre-workout and endurance formulations, the product offers a clean-label alternative for fitness enthusiasts seeking stimulant-free nitric oxide boosters. This launch addresses increasing consumer demand for transparency, plant-based supplements, and functional performance products
- In February 2025, NOW Foods, a prominent U.S.-based dietary supplement brand, expanded its L-citrulline product line with dual-layer tablets that offer extended-release benefits. The innovation aims to enhance sustained nitric oxide levels throughout physical activity, appealing to athletes and older adults alike. This strategic product enhancement positions NOW Foods to capitalize on the longevity and active aging trends in the nutraceutical industry
- In January 2025, Glanbia Nutritionals announced a strategic partnership with a leading South Korean distributor to expand the availability of its branded L-citrulline ingredients across the Asia-Pacific region. This collaboration enables localized market penetration and supports Glanbia’s growth strategy in emerging markets with rising interest in performance nutrition and clinical-grade amino acids
- In January 2025, PureBulk, Inc., an online bulk supplement provider, introduced a subscription-based direct-to-consumer model for its L-citrulline products. This move reflects evolving consumer preferences for convenience, cost-effectiveness, and personalized supplementation. The subscription service includes customizable dosages, educational resources, and loyalty incentives aimed at enhancing customer retention and engagement
