Global Long Read Sequencing Market - Industry Trends and Forecast to 2030

Global Long Read Sequencing Market, By Technology (Single-Molecule Real- Time Sequencing, Nanopore Sequencing, Synthetic Long Read Sequencing and Others), Product (Instruments, Consumables and Services), Application (Whole Genome Sequencing, Epigenetics, RNA Sequencing, Complex Population, Targeted Sequencing and Others), Workflow (Pre-Sequencing, Sequencing and Data Analysis), End-user (Academic and Research Institutes, Clinical Laboratories, Hospitals, Pharma and Biotech Entities and Others) – Industry Trends and Forecast to 2030.

Long Read Sequencing Market Analysis and Size

Long-read sequencing is a next-generation sequencing (NGS) technology that allows the reading of longer DNA sequences compared to short-read sequencing methods. This technology has gained prominence in genomics and various life sciences applications due to its ability to provide more comprehensive genomic information, including structural variations, complex regions, and long-range information. Long-read sequencing technology plays a crucial role in advancing genomics research, enabling scientists to study complex genomes, uncover novel genetic variations, and better understand the genetic basis of diseases. This has driven its adoption in academic and research institutions.

Data Bridge Market Research analyses that the global long read sequencing market which was USD 519.64 million in 2022, and is expected to reach USD 2,533.57 million by 2030, and is expected to undergo a CAGR of 21.9% during the forecast period 2023-2030. This indicates that the market value. “Single-Molecule Real- Time Sequencing” dominates the technology segment of the global long read sequencing market owing to increasing pharmaceutical and biopharmaceutical companies investing in the preclinical screening activities which are helping them in the late-stage failures and for the development of therapeutics segment. In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.

Long Read Sequencing Market Scope and Segmentation

Market Definition

Long read sequencing, often known as third generation sequencing, is a technique for analysing large amounts of data. This is a technology in which DNA particles are sequenced right in real time and since of this straight sequencing, the long reads are produced. These sequencing reactions are approved out without the use of PCR amplification often. Long read sequencing majorly includes two techniques: single molecule real time (SMRT) sequencing and nanopore sequencing.

Global Long Read Sequencing Market Dynamics

Drivers

• Surge in Incidences of Genetic Disorders

The mounting in the number of entities facing genetic disorders would help in the growth of the market in the coming years. According to the centers for disease control and prevention, sickel cell disease affects about 100,000 people in the United States. The progress in the patients would draw the attention of common of the key companies to bring up keys and hence, is anticipated to propel the growth of the market in the near upcoming.

• Rising Utilization of Sequence Analysis Methodologies

The increasing acceptance of modern approaches for medical diagnostics, represents one of the key factors bolstering the market growth. The escalating demand for LRS technology can also be attributed to its portability and real-time speed. It is also used to produce an accurate reference map of the centromere of the chromosomes. Apart from this, various biotech companies are developing innovative technologies that combine a new library prep method and genome analysis tools. In line with this, several studies indicate that LRS technology plays a crucial role in discovering novel pathogenic mutations in human diseases with unknown genetic causes. This presents numerous opportunities to researchers for using the technology in whole-genome sequencing (WGS) and enabling advancements in medical genetics. Furthermore, the rising utilization of sequence analysis methodologies in medical institutes for academic purposes, in confluence with the increasing investments in research and development (R&D) activities, is anticipated to drive the market growth further.

Opportunity

• Rising Investments for R & D Activities

An increase in leading manufacturers' R&D investments in long-read sequencing technologies, combined with a growth in the prevalence of genetic disorders, is likely to propel the market forward significantly. Long read technique is mostly employed to investigate genetic disorders for which disease loci are either strongly suspected or known. Long-read sequencing methods have the potential to alleviate some of the drawbacks of next-generation sequencing-based clinical disease research. Long read sequencing technologies have a significant advantage over their competitors since they use longer reads that come from a single DNA molecule.

Restraint/Challenge

• Higher Cost per Base Relative to Short Read Sequencing

The global long-read sequencing market is facing trials due to lack of highly cutting-edge genomic testing centers, expensive installation process, and absence of expert specific with progressive diagnostic abilities.

Recent Development

• In March 2019, Flongle was developed by Oxford Nanopore to analyse short DNA/RNA sequences quickly. Flongle is an adaptor that works with the GridION X5 desktop and MinION portable sequencing techniques. Small Flange cells that can yield as much as 1.8 Gb of sequence data with headroom for more than 3 Gb. This merchandise promotion will help in the firming of the company’s product portfolio.

Global Long Read Sequencing Market Scope

The global long read sequencing market is segmented on the basis of technology, product, workflow, application and end-user. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Technology

• Nanopore Sequencing
• Single Molecule Real Time Sequencing (SMRT)

Product

• Consumables
• Instruments
• Services

Work Flow

• Sequencing
• Data Analysis
• Pre-Sequencing

Application

• Tandem Repeat Sequencing
• Identification and Fine Mapping of Structural Variation
• Viral and Microbial Sequencing
• Reproductive Genomics
• Pseudogene Discrimination
• Others

End-User

• Hospitals and Clinics
• Pharmaceutical and Biotechnology Industry
• Others

Global Long Read Sequencing Market Regional Analysis/Insights

The global long read sequencing market is analysed and market size insights and trends are provided by country, technology, product, workflow, application and end-user as referenced above.

The countries covered in the global long read sequencing market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America is dominating the global long read sequencing market due to large number of companies, R&D capabilities and development in the global long read sequencing market during the forecasted period 2023-2030.

Asia-Pacific will raise with developed rate during the forecast period 2023-2030 due to the increasing diffusion of leading players into emerging Asian markets and cumulative strength in the project of forward-thinking diagnostics will rise the regional market.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.

Healthcare Infrastructure Growth Installed Base and New Technology Penetration

The global long read sequencing market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipment, installed base of different kind of products for global long read sequencing market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the global long read sequencing market. The data is available for historic period 2015-2020.

Competitive Landscape and Global Long read sequencing market Share Analysis

The global long read sequencing market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to global long read sequencing market.

Some of the major players operating in the global long read sequencing market are:

• Illumina, Inc. (U.S.)
• MicrobesNG (U.S.)
• Roche Sequencing (U.S.)
• F. Hoffmann-La Roche Ltd. (Switzerland)
• PacBio (U.S.)
• Oxford Nanopore Technologies plc (U.K.)
• Quantapore, Inc. (U.S.)
• FG Technologies (Switzerland)
• BaseClear B.V (Netherlands)
• INSTITUTE OF INTEGRATIVE CELL BIOLOGY AND PHYSIOLOGY (France)
• The Garvan Institute (Australia)
• France Génomique (France)
• Takara Holdings Inc. (Japan)
• Genexa AG (Switzerland)