Global Mechanistic Target of Rapamycin (mTOR) Inhibitors Market, By Indication (Organ Transplant, Oncology, Others), Product Types (Afinitor, Rapamune, Torisel, Zortress, Others), Route of Administration (Oral, Parenteral, Others), End-Users (Hospitals, Specialty Clinics, Others), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Others), Industry Trends and Forecast to 2029
Market Analysis and Insights
Over the recent years, the mechanistic target of rapamycin (mTOR) inhibitors has gained immense popularity for its role in regulating various biological processes and the advancements in assessing mTOR participants in renal pathological and physiological mechanisms has helped the market to expand at a considerable growth. The market is estimated to show a significant growth within the forecasted period.
- Data Bridge Market Research analyses that the mechanistic target of rapamycin (mTOR) inhibitors market will grow at a CAGR of 3.5% during the forecast period of 2022 to 2029. The “rapamune” accounts for the largest product type segment in the mechanistic target of rapamycin (mTOR) inhibitors market within the forecasted period.
Market Definition
Rapamycin (mTOR) inhibitors are a type of drug that inhibits or blocks the action of the mammalian target of rapamycin (mTOR). Rapamycin's mammalian target is a protein kinase that regulates growth factors, cell growth, and angiogenesis. Anti-neoplastic and immunosuppressive properties are found in rapamycin (mTOR) inhibitors.
Mechanistic Target of Rapamycin (mTOR) Inhibitors Market Dynamics
Drivers
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Growing Cases Of Organ Transplant
The rise in growing cases of cancer and organ transplant will result in the expansion of the growth rate of the treatment market.
Moreover, the sudden increase of cell growth and alteration in metabolic functions are also the growth determinants which bolster the growth of the market. Also, the availability of the treatment will further enhance the growth of mechanistic target of rapamycin (mTOR) inhibitors market.
Furthermore, the availability of the cost effective drugs can be considered as one of the progressive factors which will positively impact the mechanistic target of rapamycin (mTOR) inhibitors market's growth rate.
Opportunities
Moreover, the introduction of new and innovative technologies and advancements in assessing mTOR participants in renal pathological and physiological mechanisms have will boost new opportunities for the market's growth rate. Also, the increased government funding and awareness programs and developments in healthcare technology will escalate the growth rate mechanistic target of rapamycin (mTOR) inhibitors market in future.
Restraints/Challenges
However, lack of novel treatment, high cost of the research and development and higher cost of interventional devices will impede the growth rate of mechanistic target of rapamycin (mTOR) inhibitors market. Additionally, the stringent FDA guideline for the approval for the treatment is projected to hamper the growth of the market growth.
This mechanistic target of rapamycin (mTOR) inhibitors market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on mechanistic target of rapamycin (mTOR) inhibitors market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.
Patient Epidemiology Analysis
The mechanistic target of rapamycin (mTOR) inhibitors are basically the serine/threonine protein kinase that is inhibited by rapamycin. According to research, the annual cancer cases are expected rise from14 million to 22 million in next two decades.
Mechanistic target of rapamycin (mTOR) inhibitors market also provides you with detailed market analysis for patient analysis, prognosis and cures. Prevalence, incidence, mortality, adherence rates are some of the data variables that are available in the report. Direct or indirect impact analyses of epidemiology to market growth are analyzed to create a more robust and cohort multivariate statistical model for forecasting the market in the growth period.
COVID-19 Impact on Mechanistic Target of Rapamycin (mTOR) Inhibitors Market
Healthcare and pharmaceutical industries were heavily impacted by the COVID-19. The mechanistic target of rapamycin (mTOR) inhibitors market was however affected negatively by the sudden emergence of the COVID-19 due to the implementation of strict lockdowns and isolation regulations across the globe. The restrictions further complicated the disease management and caused delays in the import and export of drugs and medicines for the mechanistic target of rapamycin (mTOR) inhibitors as the entire supply chain has been disrupted, which has had a negative impact on the market. Moreover, the market players are increasingly looking into the potential of mTOR inhibitors as a COVID-19 treatment alternative. Because of the ambiguous results of clinical trials and the early stages of research, adoption of mTOR-dependent pathways as COVID-19 therapy is expected to be slow.
Global Mechanistic Target of Rapamycin (mTOR) Inhibitors Market Scope
The mechanistic target of rapamycin (mTOR) inhibitors market is segmented on the basis of indication, product types, route of administration, end-users and distribution channel. The growth amongst these segments will help you analyze meager growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.
Indication
- Organ Transplant
- Oncology
- Others
On the basis of indication, mechanistic target of rapamycin (mTOR) inhibitors market is segmented into organ transplant, oncology and others.
Product Types
- Afinitor
- Rapamune
- Torisel
- Zortress
- Others
On the basis of product types, mechanistic target of rapamycin (mTOR) inhibitors market is segmented into afinitor, rapamune, torisel, zortress and others. Rapamune is expected to show a significant share within the product type segment within forecasted period.
Route of Administration
- Oral
- Parenteral
- Others
On the basis of route of administration, the mechanistic target of rapamycin (mTOR) inhibitors market is segmented into oral, parenteral and others.
End-Users
- Hospitals
- Specialty Clinics
- Others
On the basis of end-users, the mechanistic target of rapamycin (mTOR) inhibitors market is segmented into hospitals, specialty clinics and others.
Distribution Channel
- Hospital Pharmacy
- Retail Pharmacy
- Others
On the basis of distribution channel, the mechanistic target of rapamycin (mTOR) inhibitors market is segmented into hospital pharmacy, retail pharmacy and others.
Mechanistic Target of Rapamycin (mTOR) Inhibitors Market Regional Analysis/Insights
The mechanistic target of rapamycin (mTOR) inhibitors market is analyzed and market size insights and trends are provided by country, indication, product types, route of administration, end-users and distribution channel as referenced above.
The countries covered in the mechanistic target of rapamycin (mTOR) inhibitors market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.
North America dominates the mechanistic target of rapamycin (mTOR) inhibitors market in terms of market share and market revenue and will continue to flourish its dominance during the forecast period. This is due to the presence of key manufacture of the product, high research and development and healthcare expenditure and skilled professionals in this region. Asia-Pacific on the other hand is projected to exhibit the highest growth rate during the forecast period due to the high prevalence cases of cancer and number of generic drugs in the region.
The country section of the report also provides individual market impacting factors and changes in regulations in the market domestically that impacts the current and future trends of the market. Data points such as new sales, replacement sales, country demographics, disease epidemiology and import-export tariffs are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of sales channels are considered while providing forecast analysis of the country data.
Competitive Landscape and Mechanistic Target of Rapamycin (mTOR) Inhibitors Market Share Analysis
The mechanistic target of rapamycin (mTOR) inhibitors market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to mechanistic target of rapamycin (mTOR) inhibitors market.
Some of the major players operating in the mechanistic target of rapamycin (mTOR) inhibitors market are Novartis AG, Merck & Co Inc., Accord Healthcare, Hikma Pharmaceuticals PLC, Par Pharmaceuticals, Teva Pharmaceuticals Industries Ltd., Dr. Reddy’s Laboratories Ltd., Zydus Pharmaceuticals, Inc., Pfizer Inc., AstraZeneca, Bristol-Myers Squibb Company, AbbVie Inc., Eli Lilly and Company, VTV Therapeutics, H. Lundbeck A/S, TauRx Pharmaceuticals Ltd, DAIICHI SANKYO COMPANY LIMITED, GlaxoSmithKline Plc, Echo Pharma, Takeda Pharmaceutical Company Limited, Bayer AG, Biogen, WOCKHARDT BIO AG., Sun Pharmaceuticals Industries Ltd., and Allergan among others.
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Table of Content
1 INTRODUCTION
1.1 OBJECTIVES OF THE STUDY
1.2 MARKET DEFINITION
1.3 OVERVIEW OF GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET
1.4 CURRENCY AND PRICING
1.5 LIMITATION
1.6 MARKETS COVERED
2 MARKET SEGMENTATION
2.1 KEY TAKEAWAYS
2.2 ARRIVING AT THE GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET SIZE
2.2.1 VENDOR POSITIONING GRID
2.2.2 TECHNOLOGY LIFE LINE CURVE
2.2.3 TRIPOD DATA VALIDATION MODEL
2.2.4 MARKET GUIDE
2.2.5 MULTIVARIATE MODELLING
2.2.6 TOP TO BOTTOM ANALYSIS
2.2.7 CHALLENGE MATRIX
2.2.8 APPLICATION COVERAGE GRID
2.2.9 STANDARDS OF MEASUREMENT
2.2.10 VENDOR SHARE ANALYSIS
2.2.11 EPIDEMIOLOGY MODELING
2.2.12 DATA POINTS FROM KEY PRIMARY INTERVIEWS
2.2.13 DATA POINTS FROM KEY SECONDARY DATABASES
2.3 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET: RESEARCH SNAPSHOT
2.4 ASSUMPTIONS
3 EXECUTIVE SUMMARY
4 PREMIUM INSIGHTS
4.1 PORTER'S 5 FORCES
4.2 PESTEL ANALYSIS
5 EPIDEMIOLOGY
5.1 INCIDENCE OF ALL BY GENDER
5.2 TREATMENT RATE
5.3 MORTALITY RATE
5.4 DRUG ADHERENCE AND THERAPY SWITCH MODEL
5.5 PATEINT TREATMENT SUCCESS RATES
6 INDUSTRY INSIGHTS
6.1 PATENT ANALYSIS
6.2 DRUG TREATMENT RATE BY MATURED MARKETS
6.3 DEMOGRAPHIC TRENDS: IMPACTS ON ALL INCIDENCE RATES
6.4 PATIENT FLOW DIAGRAM
6.5 KEY PRICING STRATEGIES
6.6 KEY PATIENT ENROLLMENT STRATEGIES
6.7 INTERVIEWS WITH ONCOLOGIST
6.8 OTHER KOL SNAPSHOTS
7 REGULATORY SCENARIO
7.1 FDA APPROVALS
7.2 EMA APPROVALS
8 MERGERS AND ACQUISITION
8.1 LICENSING
8.2 COMMERCIALIZATION AGREEMENTS
9 PIPELINE ANALYSIS
9.1 CLINICAL TRIALS AND PHASE ANALYSIS
9.2 DRUG THERAPY PIPELINE
9.2.1 FIRST GENERATION MTOR INHIBIBITORS
9.2.1.1. PHASE I CANDIDDATE (NABRAPAMYCIN)
9.2.2 SECOND GENRATION MTOR INHIBITORS
9.2.2.1. MTPR AND PI3K DUAL SPECIFICITY INHIBITORS
9.2.2.1.1. PHASE II CANDIDATES
9.2.2.1.1.1 NVP-BEZ235
9.2.2.1.1.2 XL765
9.2.2.1.1.3 OTHERS
9.2.2.1.2. PHASE I CANDIDATES
9.2.2.1.2.1 SF-1126
9.2.2.1.2.2 OTHERS
9.2.2.1.3. PRECLINICAL CANDIDATES
9.2.2.1.3.1 P1-103
9.2.2.1.3.2 WJD008
9.2.2.1.3.3 OTHERS
9.2.2.2. SELECTIVE MTORC1/2 INHIBITORS
9.2.2.2.1. PHASE I CANDIDATES
9.2.2.2.1.1 INK128
9.2.2.2.1.2 AZD8055
9.2.2.2.1.3 OSI-027
9.2.2.2.1.4 OTHERS
9.2.2.2.2. PRECLINICAL CANDIDATES
9.2.2.2.2.1 TORIN 1
9.2.2.2.2.2 PP242
9.2.2.2.2.3 PP30
9.2.2.2.2.4 KU-0063794
9.2.2.2.2.5 WYE-354
9.2.2.2.2.6 WAY-600
9.2.2.2.2.7 WYE-687
9.2.2.2.2.8 OTHERS
9.3 OTHERS
10 MARKET OVERVIEW
10.1 DRIVERS
10.2 RESTRAINS
10.3 OPPURTUNITY
10.4 CHALLENGES
11 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY TYPE
11.1 OVERVIEW
11.2 FIRST GENERATION MTOR INHIBITORS
11.2.1 BY DRUGS
11.2.1.1. RAPAMYCIN
11.2.1.2. TEMSIROLIMUS
11.2.1.3. EVEROLIMUS
11.2.1.4. DEFOROLIMUS
11.2.2 BY DRUG TYPE
11.2.2.1. GENERICS
11.2.2.2. BRANDED
11.2.2.2.1. RAPAMUNE
11.2.2.2.2. TORISEL
11.2.2.2.3. AFINITOR
11.2.2.2.4. ZORTESS
11.2.2.2.5. AFINTOR DISPERZ
11.2.2.2.6. OTHERS
11.3 OTHERS
12 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY ROUTE OF ADMINISTRATION
12.1 OVERVIEW
12.2 ORAL
12.3 PARENTERAL
12.4 OTHERS
13 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY INDICATION
13.1 OVERVIEW
13.2 RENAL CARCINOMA
13.3 RENAL TRANSPLANTATION
13.4 SOFT TISSUES AND BONE SARCOMAS
13.5 METASTATIC PANCREATIC NEUROENDOCRINE TUMORS
13.6 BREAST CANCER
13.7 COLON CANCER
13.8 OTHERS
14 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY END USER
14.1 OVERVIEW
14.2 HOSPITALS
14.3 SPECIALTY CLINICS
14.4 CANCER RESEARCH INSTITUTES
14.5 OTHERS
15 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY DISTRIBUTION CHANNEL
15.1 OVERVIEW
15.2 HOSPITAL PHARMACY
15.3 ONLINE PHARMACY
15.4 RETAIL PHARMACY
16 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY GEOGRAPHY
16.1 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, (ALL SEGMENTATION PROVIDED ABOVE IS REPRESENTED IN THIS CHAPTER BY COUNTRY)
16.2 NORTH AMERICA
16.2.1 U.S.
16.2.1.1. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY TYPE
16.2.1.2. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY ROUTE OF ADMINISTRATION
16.2.1.3. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY INDICATION
16.2.1.4. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY END USER
16.2.1.5. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY DISTRIBUTION CHANNEL
16.2.2 CANADA
16.2.3 MEXICO
16.2.4 DOMINICAN REPUBLIC
16.2.5 JAMAICA
16.2.6 PANAMA
16.3 EUROPE
16.3.1 GERMANY
16.3.2 FRANCE
16.3.3 U.K.
16.3.4 HUNGARY
16.3.5 LITHUANIA
16.3.6 AUSTRIA
16.3.7 IRELAND
16.3.8 NORWAY
16.3.9 POLAND
16.3.10 ITALY
16.3.11 SPAIN
16.3.12 RUSSIA
16.3.13 TURKEY
16.3.14 NETHERLANDS
16.3.15 SWITZERLAND
16.3.16 REST OF EUROPE
16.4 ASIA-PACIFIC
16.4.1 JAPAN
16.4.2 CHINA
16.4.3 TAIWAN
16.4.4 SOUTH KOREA
16.4.5 INDIA
16.4.6 AUSTRALIA
16.4.7 SINGAPORE
16.4.8 THAILAND
16.4.9 MALAYSIA
16.4.10 INDONESIA
16.4.11 PHILIPPINES
16.4.12 VIETNAM
16.4.13 REST OF ASIA-PACIFIC
16.5 SOUTH AMERICA
16.5.1 BRAZIL
16.5.2 ECUADOR
16.5.3 CHILE
16.5.4 COLOMBIA
16.5.5 VENEZUELA
16.5.6 ARGENTINA
16.5.7 PERU
16.5.8 CURAÇAO
16.5.9 PARAGUAY
16.5.10 URUGUAY
16.5.11 TRINIDAD AND TOBAGO
16.5.12 REST OF SOUTH AMERICA
16.6 MIDDLE EAST AND AFRICA
16.6.1 SOUTH AFRICA
16.6.2 SAUDI ARABIA
16.6.3 UAE
16.6.4 EGYPT
16.6.5 KUWAIT
16.6.6 ISRAEL
16.6.7 BOLIVIA
16.6.8 REST OF MIDDLE EAST AND AFRICA
16.7 KEY PRIMARY INSIGHTS: BY MAJOR COUNTRIES
17 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, SWOT AND DBMR ANALYSIS
18 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, COMPANY LANDSCAPE
18.1 COMPANY SHARE ANALYSIS: GLOBAL
18.2 COMPANY SHARE ANALYSIS: NORTH AMERICA
18.3 COMPANY SHARE ANALYSIS: EUROPE
18.4 COMPANY SHARE ANALYSIS: ASIA-PACIFIC
18.5 MERGERS & ACQUISITIONS
18.6 NEW PRODUCT DEVELOPMENT & APPROVALS
18.7 EXPANSIONS
18.8 REGULATORY CHANGES
18.9 PARTNERSHIP AND OTHER STRATEGIC DEVELOPMENTS
19 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, COMPANY PROFILE
19.1 PFIZER,INC
19.1.1 COMPANY OVERVIEW
19.1.2 REVENUE ANALYSIS
19.1.3 GEOGRAPHIC PRESENCE
19.1.4 PRODUCT PORTFOLIO
19.1.5 RECENT DEVELOPMENTS
19.2 NOVARTIS AG
19.2.1 COMPANY OVERVIEW
19.2.2 REVENUE ANALYSIS
19.2.3 GEOGRAPHIC PRESENCE
19.2.4 PRODUCT PORTFOLIO
19.2.5 RECENT DEVELOPMENTS
19.3 TAKEDA PHARMACEUTICALS
19.3.1 COMPANY OVERVIEW
19.3.2 REVENUE ANALYSIS
19.3.3 GEOGRAPHIC PRESENCE
19.3.4 PRODUCT PORTFOLIO
19.3.5 RECENT DEVELOPMENTS
19.4 CELGENE CORP.
19.4.1 COMPANY OVERVIEW
19.4.2 REVENUE ANALYSIS
19.4.3 GEOGRAPHIC PRESENCE
19.4.4 PRODUCT PORTFOLIO
19.4.5 RECENT DEVELOPMENTS
19.5 MERCK & CO, INC
19.5.1 COMPANY OVERVIEW
19.5.2 REVENUE ANALYSIS
19.5.3 GEOGRAPHIC PRESENCE
19.5.4 PRODUCT PORTFOLIO
19.5.5 RECENT DEVELOPMENTS
19.6 EXELIXIS
19.6.1 COMPANY OVERVIEW
19.6.2 REVENUE ANALYSIS
19.6.3 GEOGRAPHIC PRESENCE
19.6.4 PRODUCT PORTFOLIO
19.6.5 RECENT DEVELOPMENTS
19.7 ASTRAZENCA
19.7.1 COMPANY OVERVIEW
19.7.2 REVENUE ANALYSIS
19.7.3 GEOGRAPHIC PRESENCE
19.7.4 PRODUCT PORTFOLIO
19.7.5 RECENT DEVELOPMENTS
19.8 SEMAFORE PHARMACEUTICALS , INC
19.8.1 COMPANY OVERVIEW
19.8.2 REVENUE ANALYSIS
19.8.3 GEOGRAPHIC PRESENCE
19.8.4 PRODUCT PORTFOLIO
19.8.5 RECENT DEVELOPMENTS
19.9 ASTELLAS PHARMA INC
19.9.1 COMPANY OVERVIEW
19.9.2 REVENUE ANALYSIS
19.9.3 GEOGRAPHIC PRESENCE
19.9.4 PRODUCT PORTFOLIO
19.9.5 RECENT DEVELOPMENTS
*NOTE: THE COMPANIES PROFILED IS NOT EXHAUSTIVE LIST AND IS AS PER OUR PREVIOUS CLIENT REQUIREMENT. WE PROFILE MORE THAN 100 COMPANIES IN OUR STUDY AND HENCE THE LIST OF COMPANIES CAN BE MODIFIED OR REPLACED ON REQUEST
20 RELATED REPORTS
21 CONCLUSION
22 QUESTIONNAIRE
23 ABOUT DATA BRIDGE MARKET RESEARCH
Research Methodology
Data collection and base year analysis are done using data collection modules with large sample sizes. The stage includes obtaining market information or related data through various sources and strategies. It includes examining and planning all the data acquired from the past in advance. It likewise envelops the examination of information inconsistencies seen across different information sources. The market data is analysed and estimated using market statistical and coherent models. Also, market share analysis and key trend analysis are the major success factors in the market report. To know more, please request an analyst call or drop down your inquiry.
The key research methodology used by DBMR research team is data triangulation which involves data mining, analysis of the impact of data variables on the market and primary (industry expert) validation. Data models include Vendor Positioning Grid, Market Time Line Analysis, Market Overview and Guide, Company Positioning Grid, Patent Analysis, Pricing Analysis, Company Market Share Analysis, Standards of Measurement, Global versus Regional and Vendor Share Analysis. To know more about the research methodology, drop in an inquiry to speak to our industry experts.
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