Table of Content
1 INTRODUCTION
1.1 OBJECTIVES OF THE STUDY
1.2 MARKET DEFINITION
1.3 OVERVIEW OF GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET
1.4 CURRENCY AND PRICING
1.5 LIMITATION
1.6 MARKETS COVERED
2 MARKET SEGMENTATION
2.1 KEY TAKEAWAYS
2.2 ARRIVING AT THE GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET SIZE
2.2.1 VENDOR POSITIONING GRID
2.2.2 TECHNOLOGY LIFE LINE CURVE
2.2.3 TRIPOD DATA VALIDATION MODEL
2.2.4 MARKET GUIDE
2.2.5 MULTIVARIATE MODELLING
2.2.6 TOP TO BOTTOM ANALYSIS
2.2.7 CHALLENGE MATRIX
2.2.8 APPLICATION COVERAGE GRID
2.2.9 STANDARDS OF MEASUREMENT
2.2.10 VENDOR SHARE ANALYSIS
2.2.11 EPIDEMIOLOGY MODELING
2.2.12 DATA POINTS FROM KEY PRIMARY INTERVIEWS
2.2.13 DATA POINTS FROM KEY SECONDARY DATABASES
2.3 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET: RESEARCH SNAPSHOT
2.4 ASSUMPTIONS
3 EXECUTIVE SUMMARY
4 PREMIUM INSIGHTS
4.1 PORTER'S 5 FORCES
4.2 PESTEL ANALYSIS
5 EPIDEMIOLOGY
5.1 INCIDENCE OF ALL BY GENDER
5.2 TREATMENT RATE
5.3 MORTALITY RATE
5.4 DRUG ADHERENCE AND THERAPY SWITCH MODEL
5.5 PATEINT TREATMENT SUCCESS RATES
6 INDUSTRY INSIGHTS
6.1 PATENT ANALYSIS
6.2 DRUG TREATMENT RATE BY MATURED MARKETS
6.3 DEMOGRAPHIC TRENDS: IMPACTS ON ALL INCIDENCE RATES
6.4 PATIENT FLOW DIAGRAM
6.5 KEY PRICING STRATEGIES
6.6 KEY PATIENT ENROLLMENT STRATEGIES
6.7 INTERVIEWS WITH ONCOLOGIST
6.8 OTHER KOL SNAPSHOTS
7 REGULATORY SCENARIO
7.1 FDA APPROVALS
7.2 EMA APPROVALS
8 MERGERS AND ACQUISITION
8.1 LICENSING
8.2 COMMERCIALIZATION AGREEMENTS
9 PIPELINE ANALYSIS
9.1 CLINICAL TRIALS AND PHASE ANALYSIS
9.2 DRUG THERAPY PIPELINE
9.2.1 FIRST GENERATION MTOR INHIBIBITORS
9.2.1.1. PHASE I CANDIDDATE (NABRAPAMYCIN)
9.2.2 SECOND GENRATION MTOR INHIBITORS
9.2.2.1. MTPR AND PI3K DUAL SPECIFICITY INHIBITORS
9.2.2.1.1. PHASE II CANDIDATES
9.2.2.1.1.1 NVP-BEZ235
9.2.2.1.1.2 XL765
9.2.2.1.1.3 OTHERS
9.2.2.1.2. PHASE I CANDIDATES
9.2.2.1.2.1 SF-1126
9.2.2.1.2.2 OTHERS
9.2.2.1.3. PRECLINICAL CANDIDATES
9.2.2.1.3.1 P1-103
9.2.2.1.3.2 WJD008
9.2.2.1.3.3 OTHERS
9.2.2.2. SELECTIVE MTORC1/2 INHIBITORS
9.2.2.2.1. PHASE I CANDIDATES
9.2.2.2.1.1 INK128
9.2.2.2.1.2 AZD8055
9.2.2.2.1.3 OSI-027
9.2.2.2.1.4 OTHERS
9.2.2.2.2. PRECLINICAL CANDIDATES
9.2.2.2.2.1 TORIN 1
9.2.2.2.2.2 PP242
9.2.2.2.2.3 PP30
9.2.2.2.2.4 KU-0063794
9.2.2.2.2.5 WYE-354
9.2.2.2.2.6 WAY-600
9.2.2.2.2.7 WYE-687
9.2.2.2.2.8 OTHERS
9.3 OTHERS
10 MARKET OVERVIEW
10.1 DRIVERS
10.2 RESTRAINS
10.3 OPPURTUNITY
10.4 CHALLENGES
11 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY TYPE
11.1 OVERVIEW
11.2 FIRST GENERATION MTOR INHIBITORS
11.2.1 BY DRUGS
11.2.1.1. RAPAMYCIN
11.2.1.2. TEMSIROLIMUS
11.2.1.3. EVEROLIMUS
11.2.1.4. DEFOROLIMUS
11.2.2 BY DRUG TYPE
11.2.2.1. GENERICS
11.2.2.2. BRANDED
11.2.2.2.1. RAPAMUNE
11.2.2.2.2. TORISEL
11.2.2.2.3. AFINITOR
11.2.2.2.4. ZORTESS
11.2.2.2.5. AFINTOR DISPERZ
11.2.2.2.6. OTHERS
11.3 OTHERS
12 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY ROUTE OF ADMINISTRATION
12.1 OVERVIEW
12.2 ORAL
12.3 PARENTERAL
12.4 OTHERS
13 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY INDICATION
13.1 OVERVIEW
13.2 RENAL CARCINOMA
13.3 RENAL TRANSPLANTATION
13.4 SOFT TISSUES AND BONE SARCOMAS
13.5 METASTATIC PANCREATIC NEUROENDOCRINE TUMORS
13.6 BREAST CANCER
13.7 COLON CANCER
13.8 OTHERS
14 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY END USER
14.1 OVERVIEW
14.2 HOSPITALS
14.3 SPECIALTY CLINICS
14.4 CANCER RESEARCH INSTITUTES
14.5 OTHERS
15 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY DISTRIBUTION CHANNEL
15.1 OVERVIEW
15.2 HOSPITAL PHARMACY
15.3 ONLINE PHARMACY
15.4 RETAIL PHARMACY
16 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY GEOGRAPHY
16.1 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, (ALL SEGMENTATION PROVIDED ABOVE IS REPRESENTED IN THIS CHAPTER BY COUNTRY)
16.2 NORTH AMERICA
16.2.1 U.S.
16.2.1.1. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY TYPE
16.2.1.2. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY ROUTE OF ADMINISTRATION
16.2.1.3. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY INDICATION
16.2.1.4. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY END USER
16.2.1.5. U.S. MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, BY DISTRIBUTION CHANNEL
16.2.2 CANADA
16.2.3 MEXICO
16.2.4 DOMINICAN REPUBLIC
16.2.5 JAMAICA
16.2.6 PANAMA
16.3 EUROPE
16.3.1 GERMANY
16.3.2 FRANCE
16.3.3 U.K.
16.3.4 HUNGARY
16.3.5 LITHUANIA
16.3.6 AUSTRIA
16.3.7 IRELAND
16.3.8 NORWAY
16.3.9 POLAND
16.3.10 ITALY
16.3.11 SPAIN
16.3.12 RUSSIA
16.3.13 TURKEY
16.3.14 NETHERLANDS
16.3.15 SWITZERLAND
16.3.16 REST OF EUROPE
16.4 ASIA-PACIFIC
16.4.1 JAPAN
16.4.2 CHINA
16.4.3 TAIWAN
16.4.4 SOUTH KOREA
16.4.5 INDIA
16.4.6 AUSTRALIA
16.4.7 SINGAPORE
16.4.8 THAILAND
16.4.9 MALAYSIA
16.4.10 INDONESIA
16.4.11 PHILIPPINES
16.4.12 VIETNAM
16.4.13 REST OF ASIA-PACIFIC
16.5 SOUTH AMERICA
16.5.1 BRAZIL
16.5.2 ECUADOR
16.5.3 CHILE
16.5.4 COLOMBIA
16.5.5 VENEZUELA
16.5.6 ARGENTINA
16.5.7 PERU
16.5.8 CURAÇAO
16.5.9 PARAGUAY
16.5.10 URUGUAY
16.5.11 TRINIDAD AND TOBAGO
16.5.12 REST OF SOUTH AMERICA
16.6 MIDDLE EAST AND AFRICA
16.6.1 SOUTH AFRICA
16.6.2 SAUDI ARABIA
16.6.3 UAE
16.6.4 EGYPT
16.6.5 KUWAIT
16.6.6 ISRAEL
16.6.7 BOLIVIA
16.6.8 REST OF MIDDLE EAST AND AFRICA
16.7 KEY PRIMARY INSIGHTS: BY MAJOR COUNTRIES
17 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, SWOT AND DBMR ANALYSIS
18 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, COMPANY LANDSCAPE
18.1 COMPANY SHARE ANALYSIS: GLOBAL
18.2 COMPANY SHARE ANALYSIS: NORTH AMERICA
18.3 COMPANY SHARE ANALYSIS: EUROPE
18.4 COMPANY SHARE ANALYSIS: ASIA-PACIFIC
18.5 MERGERS & ACQUISITIONS
18.6 NEW PRODUCT DEVELOPMENT & APPROVALS
18.7 EXPANSIONS
18.8 REGULATORY CHANGES
18.9 PARTNERSHIP AND OTHER STRATEGIC DEVELOPMENTS
19 GLOBAL MECHANISTIC TARGET OF RAPAMYCIN (MTOR) INHIBITORS MARKET, COMPANY PROFILE
19.1 PFIZER,INC
19.1.1 COMPANY OVERVIEW
19.1.2 REVENUE ANALYSIS
19.1.3 GEOGRAPHIC PRESENCE
19.1.4 PRODUCT PORTFOLIO
19.1.5 RECENT DEVELOPMENTS
19.2 NOVARTIS AG
19.2.1 COMPANY OVERVIEW
19.2.2 REVENUE ANALYSIS
19.2.3 GEOGRAPHIC PRESENCE
19.2.4 PRODUCT PORTFOLIO
19.2.5 RECENT DEVELOPMENTS
19.3 TAKEDA PHARMACEUTICALS
19.3.1 COMPANY OVERVIEW
19.3.2 REVENUE ANALYSIS
19.3.3 GEOGRAPHIC PRESENCE
19.3.4 PRODUCT PORTFOLIO
19.3.5 RECENT DEVELOPMENTS
19.4 CELGENE CORP.
19.4.1 COMPANY OVERVIEW
19.4.2 REVENUE ANALYSIS
19.4.3 GEOGRAPHIC PRESENCE
19.4.4 PRODUCT PORTFOLIO
19.4.5 RECENT DEVELOPMENTS
19.5 MERCK & CO, INC
19.5.1 COMPANY OVERVIEW
19.5.2 REVENUE ANALYSIS
19.5.3 GEOGRAPHIC PRESENCE
19.5.4 PRODUCT PORTFOLIO
19.5.5 RECENT DEVELOPMENTS
19.6 EXELIXIS
19.6.1 COMPANY OVERVIEW
19.6.2 REVENUE ANALYSIS
19.6.3 GEOGRAPHIC PRESENCE
19.6.4 PRODUCT PORTFOLIO
19.6.5 RECENT DEVELOPMENTS
19.7 ASTRAZENCA
19.7.1 COMPANY OVERVIEW
19.7.2 REVENUE ANALYSIS
19.7.3 GEOGRAPHIC PRESENCE
19.7.4 PRODUCT PORTFOLIO
19.7.5 RECENT DEVELOPMENTS
19.8 SEMAFORE PHARMACEUTICALS , INC
19.8.1 COMPANY OVERVIEW
19.8.2 REVENUE ANALYSIS
19.8.3 GEOGRAPHIC PRESENCE
19.8.4 PRODUCT PORTFOLIO
19.8.5 RECENT DEVELOPMENTS
19.9 ASTELLAS PHARMA INC
19.9.1 COMPANY OVERVIEW
19.9.2 REVENUE ANALYSIS
19.9.3 GEOGRAPHIC PRESENCE
19.9.4 PRODUCT PORTFOLIO
19.9.5 RECENT DEVELOPMENTS
*NOTE: THE COMPANIES PROFILED IS NOT EXHAUSTIVE LIST AND IS AS PER OUR PREVIOUS CLIENT REQUIREMENT. WE PROFILE MORE THAN 100 COMPANIES IN OUR STUDY AND HENCE THE LIST OF COMPANIES CAN BE MODIFIED OR REPLACED ON REQUEST
20 RELATED REPORTS
21 CONCLUSION
22 QUESTIONNAIRE
23 ABOUT DATA BRIDGE MARKET RESEARCH
