Global Oligonucleotide Synthesis Linkers Market – Industry Trends and Forecast to 2029

  • Healthcare
  • Upcoming Report
  • Feb 2022
  • Global
  • 350 Pages
  • No of Tables: 220
  • No of Figures: 60
  • Healthcare
  • Upcoming Report
  • Feb 2022
  • Global
  • 350 Pages
  • No of Tables: 220
  • No of Figures: 60

Global Oligonucleotide Synthesis Linkers Market, By Type (Custom Oligonucleotides, Pre-designed Oligonucleotides), Application (Research, Diagnostics, Therapeutics), End User (Academic and Research Institutes, Pharmaceutical and Biotechnology Companies, Diagnostic Laboratories, Hospitals) – Industry Trends and Forecast to 2029.

Oligonucleotide Synthesis Linkers Market

Market Analysis and Size

The market for global oligonucleotide synthesis is estimated to increase rapidly over the forecast period, attributed to the increasing emphasis on personalized treatment. Custom medicine involves personalized treatment based on the needs and priorities of patients. Oligonucleotide synthesis provides patients with customized solutions. The development of a nonsensical RNA therapy has gained significant attention in the biotech industry.

  • Data Bridge Market Research analyses that the oligonucleotide synthesis linkers market is expected to grow at a CAGR of 9.95% during the forecast period. “Hospitals” held the largest share of the end user segment of oligonucleotide synthesis linkers market, owing to many inpatient and outpatient visits in hospitals. Also, the need for oligonucleotide drugs to meet the demand of the patient pool suffering from diseases such as Duchenne muscular dystrophy, spinal muscular atrophy, and hepatic veno-occlusive disease.

Market Definition

The chemical synthesis of relatively short segments of nucleic acids with defined chemical structure is known as oligonucleotide synthesis. The method is particularly valuable in recent laboratory practice since it allows for quick and low-cost access to custom-made oligonucleotides of the appropriate sequence. The future use of customized therapy to cure chronic illnesses is ideal because to oligonucleotide synthesis.

Oligonucleotide Synthesis Linkers Market Dynamics


  • Expansion of pharmaceutical and biotechnology sector 

The increasing number of research activities in pharmaceutical and biotechnology industry will act as major driver influencing the market’s growth rate.

  • Use of DNA microarray technology

The significant use of DNA microarray technology and the use of oligonucleotide for diagnostics therapeutics and new microchip-based oligonucleotide synthesis have led to decreased cost of oligonucleotide synthesis. Hence, these factors will further accelerate the demand for oligonucleotide synthesis linkers market.

Additionally, the rising awareness and focus on personalized medicine will act as a major driver influencing the oligonucleotide synthesis linkers market’s growth rate. The increase in utilization of synthesized oligos in therapeutic applications will increase the demand for oligonucleotide synthesis linkers and further propel the market’s growth rate. Another significant factor resulting in the expansion of market is the advancement of technology. Furthermore, surging healthcare spending capacity and advancement in healthcare infrastructure are the major drivers that will enhance the growth of market. Rapid urbanisation and rising government investments for synthetic biology and genome projects will influence the growth rate of oligonucleotide synthesis linkers market.


  • Growth in R&D activities

The rise in the number of research and development activities and increasing applications from emerging countries will provide beneficial opportunities for the oligonucleotide synthesis linkers market growth. Moreover, increasing government investments for the development of technology and healthcare infrastructure will further expand the oligonucleotide synthesis linkers market’s growth rate in the future.


On the other hand, high cost and the dearth of funding in research and development sectors in under-developed nations will obstruct the market growth. Also, delivery of oligonucleotide drugs to specific targets will pose a major challenge for oligonucleotide synthesis linkers market. However, complications involved with therapeutic oligos and the lack of skilled professionals will act as restrain and further impede the growth rate of market during the forecast period of 2022-2029.

This oligonucleotide synthesis linkers market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the oligonucleotide synthesis linkers market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

COVID-19 Impact on Oligonucleotide Synthesis Linkers Market

Since its emergence in December 2019, the COVID-19 virus has spread to nearly every country on the planet, prompting the World Health Organization (WHO) to declare it a public health emergency. A diverse group of established pharmaceutical and biopharmaceutical companies and players in the oligonucleotide synthesis market have stepped forward to support global research efforts by providing oligo products for the development of test kits, treatments, and vaccines that target the novel Coronavirus infection. The use of a wide range of oligonucleotide products such as probes and primers in COVID-19 research and other activities by market companies has helped researchers obtain a deeper understanding of the Coronavirus. As a result, the market for oligonucleotide synthesis linkers impacted positively. However, due to restrictions enforced during the COVID-19 pandemic, oligonucleotide-based medicine sales decreased slightly in 2020.

Recent Development

  • In February 2021, the Centre for Process Innovation had launched a project in Medicine Manufacturing Innovation Centre in UK. Through a collaboration with AstraZeneca, Exactmer, Novartis, and UK Research & Innovation, this project aims to transform the synthesis of oligonucleotides. As a result of this agreement, Inclisiran, a small interfering RNA used to treat atherosclerotic cardiovascular disease (ASCVD), would be the first drug produced on a commercial scale.

Global Oligonucleotide Synthesis Linkers Market Scope

The oligonucleotide synthesis linkers market is segmented on the basis of type, application and end user. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.


  • Research
  • Diagnostics
  • Therapeutics

Based on application, oligonucleotide synthesis linkers market is segmented into research, diagnostics and therapeutics. Research has been further segmented into PCR, QPCR, sequencing, gene synthesis and others. Others have been further sub segmented into nucleic acid hybridization methods and isothermal amplification methods. Therapeutics has been segmented into DNA and antisense oligonucleotide-based therapies, RNAi oligonucleotide-based therapies and CpG oligonucleotide-based therapies.


  • Custom Oligonucleotides
  • Pre-Designed Oligonucleotides

Based on type, oligonucleotide synthesis linkers market is segmented into custom oligonucleotides and pre-designed oligonucleotides.

End User

  • Academic and Research Institutes
  • Pharmaceutical and Biotechnology Companies
  • Diagnostic Laboratories
  • Hospitals

Oligonucleotide synthesis linkers market has also been segmented based on the end user into academic and research institutes, pharmaceutical and biotechnology companies, diagnostic laboratories and hospitals

Oligonucleotide Synthesis Linkers Market Regional Analysis/Insights

The oligonucleotide synthesis linkers market is analysed and market size insights and trends are provided by country, type, application and end user as referenced above.

The countries covered in the oligonucleotide synthesis linkers market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America dominates the oligonucleotide synthesis linkers market because of the greater investment in research and development and an increase in the number of oligonucleotide-based medications and therapies in this region.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.   

Healthcare Infrastructure Growth Installed Base and New Technology Penetration

The oligonucleotide synthesis linkers market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipment, installed base of different kind of products for oligonucleotide synthesis linkers market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the oligonucleotide synthesis linkers market. The data is available for historic period 2010-2020.

Competitive Landscape and Oligonucleotide Synthesis Linkers Market Share Analysis

The oligonucleotide synthesis linkers market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to oligonucleotide synthesis linkers market.

Some of the major players operating in the oligonucleotide synthesis linkers market are Agilent Technologies, Inc., ATDBio Ltd., Bio-Synthesis Inc., BioAutomation, LGC Biosearch Technologies, Sarepta Therapeutics, Kaneka Corporation, GeneDesign, Inc., General Electric, GenScript, Integrated DNA Technologies, Inc., NITTO DENKO CORPORATION., Thermo Fisher Scientific, Inc., TriLink BioTechnologies., Danaher, Maravai LifeSciences, Biogen, Eurofins Scientific, and Merck KGaA, among others.

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