Global Orbital Atherectomy Market Size, Share and Trends Analysis Report – Industry Overview and Forecast to 2033

Orbital Atherectomy Market Size

• The global orbital atherectomy market size was valued at USD 371.17 million in 2025 and is expected to reach USD 593.83 million by 2033, at a CAGR of 6.05% during the forecast period
• The market growth is largely fueled by increasing prevalence of cardiovascular and peripheral artery diseases, rising geriatric population, and growing adoption of minimally invasive procedures over traditional open surgery
• Furthermore, technological advances in orbital atherectomy devices, such as improved catheter design, enhanced plaque-modification capabilities, and integration with adjunct therapies, along with rising demand for safe, effective, and less-invasive vascular intervention solutions, are establishing orbital atherectomy as the preferred method accelerating the uptake of these solutions and significantly boosting the industry’s growth

Orbital Atherectomy Market Analysis

• Orbital atherectomy devices, used for removing calcified plaque in coronary and peripheral arteries, are increasingly vital components of minimally invasive cardiovascular interventions in both hospital and outpatient settings due to their precision, reduced procedural complications, and compatibility with adjunctive therapies
• The escalating demand for orbital atherectomy is primarily fueled by the increasing prevalence of cardiovascular and peripheral artery diseases, rising geriatric population, and a growing preference for minimally invasive procedures over traditional open surgeries
• North America dominated the orbital atherectomy market with the largest revenue share of 42.5% in 2025, characterized by advanced healthcare infrastructure, high adoption of innovative medical devices, and a strong presence of key market players, with the U.S. experiencing substantial growth in orbital atherectomy procedures, particularly in high-risk patients, driven by innovations from both established medical device companies and startups focusing on catheter design and plaque-modification technologies
• Asia-Pacific is expected to be the fastest growing region in the orbital atherectomy market during the forecast period due to increasing prevalence of cardiovascular diseases, expanding healthcare infrastructure, and rising healthcare expenditure
• Peripheral orbital atherectomy system segment dominated the orbital atherectomy market with a market share of 48.7% in 2025, driven by its established efficacy in treating calcified peripheral artery lesions and its widespread adoption across hospitals, surgical centers, and specialty clinics

Report Scope and Orbital Atherectomy Market Segmentation

Orbital Atherectomy Market Trends

Integration with Imaging and Advanced Navigation Systems

• A significant and accelerating trend in the global orbital atherectomy market is the integration of devices with advanced imaging technologies and intravascular navigation systems, enhancing precision and procedural safety in cardiovascular interventions
  • For instance, the Diamondback 360® Orbital Atherectomy System can be paired with intravascular ultrasound (IVUS) and optical coherence tomography (OCT) to provide real-time lesion assessment and optimize plaque removal during procedures
• Advanced imaging integration enables cardiologists to accurately identify calcified lesions, determine optimal atherectomy parameters, and reduce risks such as vessel perforation, ultimately improving patient outcomes
• The seamless combination of orbital atherectomy systems with imaging platforms facilitates minimally invasive procedures while maintaining high efficacy in complex coronary and peripheral artery lesions
• This trend toward more precise, data-driven, and technology-enabled interventions is fundamentally reshaping physician expectations for vascular treatment, with companies such as Cardiovascular Systems, Inc. developing systems with integrated imaging guidance to enhance procedural efficiency
• The demand for orbital atherectomy devices with imaging and navigation integration is growing rapidly across both hospital and outpatient care settings, as clinicians increasingly prioritize procedural safety, accuracy, and clinical effectiveness
• In addition, the integration of real-time procedural analytics and predictive software is allowing operators to optimize treatment strategies for individual patients, further improving success rates
• Increasing collaborations between device manufacturers and healthcare IT companies to provide connected systems and remote procedure monitoring is creating new avenues for innovation in the orbital atherectomy market

Orbital Atherectomy Market Dynamics

Driver

Rising Prevalence of Cardiovascular and Peripheral Artery Diseases

• The increasing incidence of cardiovascular and peripheral artery diseases, combined with the growing geriatric population, is a significant driver for the heightened demand for orbital atherectomy procedures
  • For instance, in March 2025, Cardiovascular Systems, Inc. announced clinical results highlighting improved outcomes in heavily calcified coronary lesions using qtheir Diamondback 360® system, reinforcing adoption in high-risk patient populations
• As clinicians seek safer and more effective alternatives to traditional angioplasty and stenting, orbital atherectomy devices offer advanced features such as precise plaque modification, minimal vessel trauma, and compatibility with adjunctive therapies
• Furthermore, the rising preference for minimally invasive procedures, coupled with expanding cardiovascular treatment facilities, is making orbital atherectomy an integral part of interventional cardiology protocols
• The ability to treat complex calcified lesions, reduce procedural complications, and improve patient recovery times are key factors propelling adoption across hospitals, surgical centers, and specialty clinics
• The growing awareness among clinicians regarding procedural efficacy, combined with supportive clinical data and increasing reimbursement policies, further contributes to market growth
• Increasing government initiatives and public health programs aimed at early detection and treatment of peripheral artery disease are driving the demand for advanced intervention devices such as orbital atherectomy systems
• The rising trend of outpatient cardiovascular procedures and ambulatory care interventions is also boosting the adoption of compact and user-friendly orbital atherectomy devices in non-hospital settings

Restraint/Challenge

High Procedure Costs and Regulatory Hurdles

• The relatively high cost of orbital atherectomy devices and associated procedures poses a significant challenge to wider market adoption, particularly in developing regions and price-sensitive healthcare settings
  • For instance, reports highlighting the overall procedural expenses compared to standard angioplasty have made some hospitals cautious in adopting orbital atherectomy solution
• Addressing cost barriers through optimized device pricing, bundled procedural solutions, and insurance coverage is crucial for increasing market penetration
• In addition, stringent regulatory approvals, varying regional medical device regulations, and the need for extensive clinical validation can delay product launches and adoption in certain countries
• While clinical efficacy is well established, the requirement for specialized training and adherence to procedural guidelines can also limit widespread utilization in smaller hospitals or ambulatory care centers
• Overcoming these challenges through cost management, streamlined regulatory strategies, and clinician education will be vital for sustained market growth
• Furthermore, potential post-procedure complications, such as vessel dissection or embolization, may limit the adoption of orbital atherectomy in certain patient populations
• Limited awareness among healthcare providers in emerging markets regarding procedural benefits and safety protocols can also restrain rapid adoption, emphasizing the need for training and awareness programs

Orbital Atherectomy Market Scope

The market is segmented on the basis of type and end user.

• By Type

On the basis of type, the orbital atherectomy market is segmented into peripheral orbital atherectomy system and coronary orbital atherectomy system. The Peripheral Orbital Atherectomy System segment dominated the market with the largest revenue share of 48.7% in 2025, driven by its established efficacy in treating calcified peripheral artery lesions and wide adoption across hospitals and surgical centers. Peripheral systems are preferred for their ability to safely modify plaque in the legs, arms, and other peripheral arteries without causing vessel trauma. The market sees strong demand for these systems due to increasing prevalence of peripheral artery disease (PAD), particularly in geriatric populations, and the growing focus on minimally invasive procedures. Clinicians also favor peripheral systems because of their compatibility with adjunctive therapies, improved catheter designs, and real-time procedural feedback. Moreover, reimbursement support in developed regions such as North America and Europe further accelerates adoption in hospital and outpatient care settings. The segment continues to attract innovations, including integration with imaging guidance and navigation tools, improving procedural precision and outcomes.

The Coronary Orbital Atherectomy System segment is anticipated to witness the fastest CAGR of 9.1% from 2026 to 2035, fueled by increasing prevalence of heavily calcified coronary artery disease and rising demand for minimally invasive interventions in cardiac catheterization labs. Coronary systems offer precise plaque modification in coronary vessels, enabling safe stent placement and improved blood flow. Hospitals and specialty cardiac centers are increasingly adopting coronary systems due to clinical evidence demonstrating reduced complications and better long-term outcomes. Advancements in device technology, such as smaller profile catheters and enhanced rotational mechanisms, are further boosting adoption. Growing awareness among cardiologists regarding the benefits of orbital atherectomy over conventional balloon angioplasty in complex coronary lesions is driving demand. In addition, increasing insurance coverage and favorable reimbursement policies in developed countries are accelerating the uptake of coronary orbital atherectomy devices.

• By End User

On the basis of end user, the orbital atherectomy market is segmented into hospitals, surgical centers, ambulatory care centers, specialty clinics, research laboratories & academic institutes, and others. The Hospitals segment dominated the market with the largest revenue share of 55.3% in 2025, driven by the presence of advanced cardiovascular treatment infrastructure and high patient volumes requiring complex vascular interventions. Hospitals are preferred end users due to their capability to handle high-risk procedures, availability of specialized catheterization labs, and access to trained interventional cardiologists. The segment benefits from ongoing clinical adoption of minimally invasive procedures and reimbursement support, particularly in North America and Europe. Hospitals also lead in the introduction of innovative orbital atherectomy technologies due to established budgets and strategic partnerships with device manufacturers. Increasing demand for outpatient procedures with hospital oversight further strengthens this segment. In addition, hospitals often serve as referral centers for complex peripheral and coronary artery disease cases, boosting procedural volumes.

The Specialty Clinics segment is expected to witness the fastest CAGR of 10.2% from 2026 to 2035, fueled by the rising number of outpatient cardiovascular care centers focusing on minimally invasive interventions. Specialty clinics are increasingly adopting orbital atherectomy devices due to lower operational costs compared to hospitals, faster patient throughput, and targeted treatment for specific vascular conditions. The growth is also supported by the expansion of cardiac care networks and the rising trend of ambulatory care for PAD and coronary interventions. Advanced device designs enabling shorter procedure times and reduced complication rates make these clinics a preferred setting for certain patient groups. Increased training programs and collaborations with device manufacturers are enabling more clinics to offer orbital atherectomy safely and effectively. Furthermore, patient preference for less invasive, outpatient-based care is contributing to the rapid adoption of specialty clinics for orbital atherectomy procedures.

Orbital Atherectomy Market Regional Analysis

• North America dominated the orbital atherectomy market with the largest revenue share of 42.5% in 2025, characterized by advanced healthcare infrastructure, high adoption of innovative medical devices, and a strong presence of key market players
• Clinicians in the region highly value the precision, safety, and plaque-modification efficiency offered by orbital atherectomy systems, as well as their compatibility with imaging tools such as IVUS and OCT for optimized procedural outcomes
• This widespread adoption is further supported by advanced healthcare infrastructure, high healthcare spending, and growing clinical preference for atherectomy-assisted interventions, establishing orbital atherectomy as a favored solution across hospitals, surgical centers, and specialized cardiovascular clinics

U.S. Orbital Atherectomy Market Insight

The U.S. orbital atherectomy market captured the largest revenue share of 83% in 2025 within North America, fueled by the high burden of calcified coronary and peripheral artery disease and the widespread adoption of minimally invasive cardiovascular procedures. Clinicians are increasingly prioritizing atherectomy-assisted interventions to improve stent deliverability and optimize outcomes in complex lesions. The strong presence of advanced catheterization labs, combined with rising preference for image-guided interventions such as IVUS and OCT, further propels market growth. Moreover, continuous technological advancements and increasing clinical evidence supporting the safety and effectiveness of orbital atherectomy are significantly contributing to the market’s expansion.

Europe Orbital Atherectomy Market Insight

The Europe orbital atherectomy market is projected to expand at a substantial CAGR throughout the forecast period, primarily driven by rising cases of peripheral artery disease and increasing demand for advanced plaque-modification technologies. The region’s stringent healthcare standards and strong focus on effective cardiovascular treatment methods are fostering adoption. European clinicians are increasingly drawn to orbital atherectomy due to its ability to treat heavily calcified lesions with minimal vascular trauma. The market is also experiencing notable growth across hospitals and specialty cardiovascular centers, where advanced image-guided interventions are becoming integral to standard care.

U.K. Orbital Atherectomy Market Insight

The U.K. orbital atherectomy market is anticipated to grow at a noteworthy CAGR during the forecast period, driven by a rising emphasis on minimally invasive cardiac and peripheral interventions. Increasing awareness of effective treatment options for heavily calcified arterial blockages is encouraging adoption in hospitals and specialty clinics. The U.K.’s growing investment in cardiovascular care infrastructure, coupled with a strong focus on improving long-term outcomes for PAD and coronary disease patients, supports market expansion. Furthermore, the integration of atherectomy systems with high-resolution imaging tools is improving clinical precision and procedural success rates.

Germany Orbital Atherectomy Market Insight

The Germany orbital atherectomy market is expected to expand at a considerable CAGR during the forecast period, fueled by a high prevalence of peripheral and coronary artery diseases and growing demand for technologically advanced treatment solutions. Germany’s well-developed healthcare infrastructure and strong culture of clinical innovation support the adoption of cutting-edge atherectomy systems. The emphasis on minimally invasive, image-guided cardiovascular procedures aligns with the rising preference for orbital atherectomy devices in both hospitals and specialty centers. In addition, German clinicians value the precision, safety, and reduced complication rates associated with these systems, driving further growth.

Asia-Pacific Orbital Atherectomy Market Insight

The Asia-Pacific orbital atherectomy market is poised to grow at the fastest CAGR of 25% during the forecast period of 2026 to 2035, driven by increasing urbanization, rising cardiovascular disease burden, and expanding access to advanced interventional cardiology procedures. Countries such as China, Japan, and India are witnessing rapid improvements in healthcare infrastructure and adoption of minimally invasive vascular treatments. Government initiatives promoting cardiovascular health and technological advancement are accelerating the use of orbital atherectomy systems. Furthermore, the growing availability of cost-effective interventional devices is expanding access to treatment across a broader patient base.

Japan Orbital Atherectomy Market Insight

The Japan orbital atherectomy market is gaining momentum due to the country’s strong technological ecosystem, high prevalence of calcified coronary lesions, and demand for precision-based cardiovascular interventions. Japanese clinicians emphasize advanced imaging integration and procedural safety, fueling adoption of orbital atherectomy in both coronary and peripheral applications. The rapid rise of smart catheterization labs and connected healthcare systems is further supporting market expansion. Moreover, Japan’s aging population is such asly to spur demand for minimally invasive, high-efficacy vascular treatment options across hospitals and specialty cardiovascular centers.

India Orbital Atherectomy Market Insight

The India orbital atherectomy market accounted for the largest market revenue share in Asia Pacific in 2025, attributed to the country’s rising incidence of peripheral artery disease, growing patient awareness, and rapid expansion of modern cardiovascular care facilities. India is emerging as a major market for minimally invasive vascular interventions, with increasing adoption of orbital atherectomy across major hospitals and specialty heart institutes. The growth is further supported by government-led healthcare modernization, improving insurance coverage, and availability of cost-effective device options. Local and global manufacturers are also strengthening their presence in India, accelerating market penetration.

Orbital Atherectomy Market Share

The Orbital Atherectomy industry is primarily led by well-established companies, including:

• Boston Scientific Corporation (U.S.)
• Abbott (U.S.)
• Medtronic (Ireland)
• Terumo Corporation (Japan)
• Cardinal Health (U.S.)
• AngioDynamics (U.S.)
• B. Braun SE (Germany)
• BIOTRONIK (Germany)
• Cook (U.S.)
• Merit Medical Systems, Inc. (U.S.)
• NIPRO CORPORATION (Japan)
• MicroPort Scientific Corporation (China)
• Lepu Medical Technology (China)
• W. L. Gore & Associates (U.S.)
• Teleflex Incorporated (U.S.)
• Olympus Corporation (Japan)
• Cordis (U.S.)
• Integra LifeSciences Corporation (U.S.)

What are the Recent Developments in Global Orbital Atherectomy Market?

• In November 2023, Cardio Flow announced the completion of the first commercial cases using the FreedomFlow platform in real-world clinical settings treating complex PAD patients with multiple blockages and demonstrating the platform’s effectiveness across a wide range of vessel sizes from ankle to hip
• In October 2023, Cardio Flow, Inc. received FDA 510(k) clearance for its FreedomFlow Orbital Atherectomy Peripheral Platform, broadening the range of atherectomy tools available to physicians treating peripheral artery disease (PAD) in the U.S.
• In April 2023, CSI announced completion of enrollment for its 2,000-patient ECLIPSE trial, evaluating the Diamondback 360 coronary system in patients with severely calcified coronary lesions a major clinical study whose results (expected in 2024) will influence future use and guidelines
• In October 2022, CSI launched the 2.00 Max Crown for its peripheral orbital atherectomy systems this expanded-crown version is designed to more effectively modify both intimal and medial calcium in mixed plaque, improving luminal gain especially in peripheral artery disease above the knee
• In August 2021, Cardiovascular Systems, Inc. (CSI) introduced its Diamondback 360 Coronary Orbital Atherectomy System in Canada for the first time, enabling treatment of severely calcified coronary artery disease cases in Canadian patients expanding availability beyond the U.S.

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