- In January 2021, the Food and Drug Administration had announced the approval of combination of nivolumab (Opdivo, Bristol-Myers Squibb Co.) and cabozantinib (Cabometyx, Exelixis) as first-line treatment for patients with advanced renal cell carcinoma (RCC). Nivolumab 240 mg every two weeks (30-minute intravenous infusion) or 480 mg every four weeks (30-minute intravenous infusion) in conjunction with cabozantinib 40 mg orally once day without food until disease progression or unacceptable toxicity is achieved is the suggested dosage.
