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Global Small Molecule Active Pharmaceutical Ingredient (API) Market – Industry Trends and Forecast to 2029

  • Healthcare
  • Upcoming Report
  • Jul 2022
  • Global
  • 350 Pages
  • No of Tables: 220
  • No of Figures: 60

Global Small Molecule Active Pharmaceutical Ingredient (API) Market – Industry Trends and Forecast to 2029

Market Size in USD Billion

CAGR - % Diagram

Diagram Forecast Period 2021–2029
Diagram Market Size (Base Year) USD 175.31 Million
Diagram Market Size (Forecast Year) USD 270.07 Million
Diagram CAGR %

Global Small Molecule Active Pharmaceutical Ingredient (API) Market, By Type (Synthetic/Chemical API, Biological API), Therapeutic Type (Autoimmune Diseases, Oncology, Metabolic Diseases, Ophthalmology, Cardiovascular Diseases, Infectious Diseases, Neurology, Respiratory Disorders, Dermatology, Urology), Manufacturing Method (In-House, Contract), Application (Clinical, Commercial) – Industry Trends and Forecast to 2029

Market Analysis and Size

Small molecules active pharmaceutical ingredient (API) are typically made up of 20–100 atoms and are well defined, purified, and studied easily. Small molecules are widely utilized to treat several illnesses and ailments and have various mechanisms of action. They can be efficient allosteric modifiers and enzyme inhibitors due to their usual physicochemical characteristics and tiny size. They can target intracellular receptors or extracellular proteins in the central nervous system, nucleus, and cytoplasm.

Data Bridge Market Research analyses that the small molecule active pharmaceutical ingredient (API) market which was USD 175.31 million in 2021, would rocket up to USD 270.07 million by 2029, and is expected to undergo a CAGR of 5.55% during the forecast period 2022 to 2029. In addition to the market insights such as market value, growth rate, market segments, geographical coverage, market players, and market scenario, the market report curated by the Data Bridge Market Research team also includes in-depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.

Report Scope and Market Segmentation

Report Metric

Details

Forecast Period

2022 to 2029

Base Year

2021

Historic Years

2020 (Customizable to 2014 - 2019)

Quantitative Units

Revenue in USD Million, Volumes in Units, Pricing in USD

Segments Covered

Type (Synthetic/Chemical API, Biological API), Therapeutic Type (Autoimmune Diseases, Oncology, Metabolic Diseases, Ophthalmology, Cardiovascular Diseases, Infectious Diseases, Neurology, Respiratory Disorders, Dermatology, Urology), Manufacturing Method (In-House, Contract), Application (Clinical, Commercial)

Countries Covered

U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America

Market Players Covered

Albemarle Corporation (U.S.), Allergan (Ireland), Aurobindo Pharma (India), Cambrex Corporation (U.S.), Dr. Reddy’s Laboratories Ltd (India), GSk plc (U.K.), Lonza (Switzerland), Merck KGaA (Germany), Novartis AG (Switzerland), Pfizer Inc. (U.S.), Siegfried Holding AG (Switzerland), Sun Pharmaceutical Industries Ltd (India), Teva Pharmaceutical Industries Ltd. (Israel), Johnson Matthey (U.K.), Gilead Sciences, Inc. (U.S.), BASF SE (Germany)

Market Opportunities

  • Increased use of breakthrough technologies
  • Rise in small scale production is anticipated

Market Definition

A low molecular weight organic compound with a size of around 1 nm is referred to as a tiny molecule active pharmaceutical ingredient (API), which helps to control the biological process. Orally administered tiny molecules can be any type, and the body will most likely take them in. Due to its tiny size and ability to quickly diffuse to the intracellular site of action, it has these qualities.

Small Molecule Active Pharmaceutical Ingredient (API) Market Dynamics

Drivers

  • Increasing prevalence of diseases

The main drivers of the small molecule API market are the rising prevalence of diseases including cancer, cardiovascular disease, and infections, the creation of businesses producing small molecule APIs, and the patent expirations of the best-selling medications. The expansion of the small molecule active pharmaceutical ingredient (API) market is accelerated by an increase in corporate partnerships, simple access to medicine in emerging economies, and rising consumer awareness of the advantages of small molecule API.

  • Technological developments in manufacturing sector

The market for small molecule APIs is impacted by the rising rate of generic pharmaceuticals and increased production of small molecule APIs due to technical advancements in the manufacturing sector. Additionally, the market for small molecule API is favourably impacted by the growing geriatric population, increase in disease and treatment awareness among people, research and development activities, improved healthcare infrastructure, and rise in healthcare spending.

  • Increase in outsourcing trend

The market's expanding need for small molecule medications and the rising outsourcing trend are two of the key drivers. The arrival of new companies that fuel the demand for raw materials like API for the low-cost synthesis of pharmaceuticals is made possible by the patent expiry of dominant compounds, which is further fuelling growth.

Opportunities

  • Increase in the small scale production    

A paradigm shift in the sector is anticipated to be triggered by the increased use of breakthrough technologies and the advent of specialised pharmaceuticals. Instead, a rise in small scale production is anticipated. Additionally, as more items are released and manufactured, adaptable production facilities and reliable procedures are being built to satisfy shifting demands.

Restraints/Challenges

On the other hand, it is anticipated that the implementation of strict regulatory requirements and the economic downturn will impede the growth of the small molecule API industry. The small molecule API industry is anticipated to face challenges from new entrants' mounting financial problems between 2022 and 2029.

This small molecule active pharmaceutical ingredient (API) market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the small molecule active pharmaceutical ingredient (API) market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

COVID-19 Impact on Small Molecule Active Pharmaceutical Ingredient (API) Market

The COVID-19 epidemic has helped the market flourish by motivating participants to spread their businesses geographically to prevent shortages. In order to tackle the illness, research into small molecule drugs like Molnupiravir is being accelerated via COVID-19. It is also being researched whether small molecule medications already on the market can be used to treat SARS-CoV-2 infection.

Recent Development

  • In January 2020, Sandoz's position in the global market for generic drugs and off-patent medications was boosted by this acquisition.

Global Small Molecule Active Pharmaceutical Ingredient (API) Market Scope

The small molecule active pharmaceutical ingredient (API) market is segmented on the basis of type, therapeutic type, manufacturing method, application. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Type

  • Synthetic/Chemical API
  • Biological API

 Therapeutic Type

  • Autoimmune Diseases
  • Oncology
  • Metabolic Diseases
  •  Ophthalmology
  • Cardiovascular Diseases
  • Infectious Diseases
  •  Neurology
  • Respiratory Disorders
  • Dermatology
  • Urology

 Manufacturing Method

  • In-House
  • Contract

 Application

  • Clinical
  • Commercial

Small Molecule Active Pharmaceutical Ingredient (API) Market Regional Analysis/Insights

The small molecule active pharmaceutical ingredient (API) market is analysed and market size insights and trends are provided by country, type, therapeutic type, manufacturing method, application as referenced above.

The countries covered in the small molecule active pharmaceutical ingredient (API) market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America dominates the small molecule active pharmaceutical ingredient (API) market due to the active pharmaceutical ingredient market in the region which is being alternated as large pharmaceutical organizations dedicate assets increasingly to the advancement of biologic services.

Asia-Pacific is expected to show significant amount of growth in the small molecule active pharmaceutical ingredient (API) market due to the actions that have been taken to encouraging generic drug growth with costing and repayment.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.

Competitive Landscape and Small Molecule Active Pharmaceutical Ingredient (API) Market Share Analysis

The small molecule active pharmaceutical ingredient (API) market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to small molecule active pharmaceutical ingredient (API) market.

Some of the major players operating in the small molecule active pharmaceutical ingredient (API) market are:

  • Albemarle Corporation (U.S.)
  • Allergan (Ireland)
  • Aurobindo Pharma (India)
  • Cambrex Corporation (U.S.)
  • Dr. Reddy’s Laboratories Ltd (India)
  • GSk plc (U.K.)
  • Lonza (Switzerland)
  • Merck KGaA (Germany)
  • Novartis AG (Switzerland)
  • Pfizer Inc. (U.S.)
  • Siegfried Holding AG (Switzerland)
  • Sun Pharmaceutical Industries Ltd (India)
  • Teva Pharmaceutical Industries Ltd. (Israel)
  • Johnson Matthey (U.K.)
  • Gilead Sciences, Inc. (U.S.)
  • BASF SE (Germany)


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Research Methodology:

Data collection and base year analysis are done using data collection modules with large sample sizes. The stage includes obtaining market information or related data through various sources and strategies. It includes examining and planning all the data acquired from the past in advance. It likewise envelops the examination of information inconsistencies seen across different information sources. The market data is analysed and estimated using market statistical and coherent models. Also, market share analysis and key trend analysis are the major success factors in the market report. To know more, please request an analyst call or drop down your inquiry.

The key research methodology used by DBMR research team is data triangulation which involves data mining, analysis of the impact of data variables on the market and primary (industry expert) validation. Data models include Vendor Positioning Grid, Market Time Line Analysis, Market Overview and Guide, Company Positioning Grid, Patent Analysis, Pricing Analysis, Company Market Share Analysis, Standards of Measurement, Global versus Regional and Vendor Share Analysis. To know more about the research methodology, drop in an inquiry to speak to our industry experts.

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Customization Available:

Data Bridge Market Research is a leader in advanced formative research. We take pride in servicing our existing and new customers with data and analysis that match and suits their goal. The report can be customized to include price trend analysis of target brands understanding the market for additional countries (ask for the list of countries), clinical trial results data, literature review, refurbished market and product base analysis. Market analysis of target competitors can be analyzed from technology-based analysis to market portfolio strategies. We can add as many competitors that you require data about in the format and data style you are looking for. Our team of analysts can also provide you data in crude raw excel files pivot tables (Fact book) or can assist you in creating presentations from the data sets available in the report.

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FREQUENTLY ASK QUESTIONS

The small molecule active pharmaceutical ingredient (API) market size will be worth USD 270.07 million by 2029.
The growth rate of the small molecule active pharmaceutical ingredient (API) market is 5.55% in the forecast by 2029.
The major small molecule active pharmaceutical ingredient (API) market are Albemarle Corporation, Allergan, Aurobindo Pharma, Cambrex Corporation, Dr. Reddy’s Laboratories Ltd, GlaxoSmithKline plc, Lonza, Merck KGaA, Novartis AG, Pfizer Inc., Siegfried Holding AG, Sun Pharmaceutical Industries Ltd, Teva Pharmaceutical Industries Ltd., Johnson Matthey, Gilead Sciences, Inc., Amneal Pharmaceuticals LLC, Breckenridge Pharmaceutical, Inc., LUPIN, Camber Pharmaceuticals, Inc., BASF SE among other domestic and global players.
Type, therapeutic type, manufacturing method, and application are the factors on which the small molecule active pharmaceutical ingredient (API) market research is based.
The increasing prevalence of diseases and technological developments in the manufacturing sector are the growth drivers of the small molecule active pharmaceutical ingredient (API) market.
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