According to a study published in Lancet: Infectious Diseases, typhoid infects 21.6 million people worldwide and kills an estimated 200,000 people each year. Furthermore, economic instability in Latin America and other developing economies has resulted in poor sanitation and restricted access to clean water and food, putting people at risk of contracting typhoid. Salmonella typhi produces typhoid fever, which causes symptoms such as a high temperature, headache, loss of appetite, constipation, and nausea. Typhoid fever is primarily spread in areas with poor sanitation and contaminated water. Typhoid fever vaccines are biological formulations that provide immunity and protection against typhoid fever in humans.



