Transplantation is a successful therapy option for end-stage organ failure. The disparity between supply and demand for human organs, on the other hand, is a bottleneck for clinical transplantation. As of January 2019, more than 113,000 people were on the transplant waiting list in the United States, according to the US Government Information on Organ Donation and Transplantation, whereas only 36,528 transplants were done in 2018.
