North America Active Pharmaceutical Ingredients (API) Market, By Molecule (Small Molecule, Large Molecule), Type (Innovative Active Pharmaceutical Ingredients, Generic Innovative Active Pharmaceutical Ingredients), Type of Manufacturer (Captive API Manufacturer, Merchant API Manufacturer), Synthesis (Synthetic Active Pharmaceutical Ingredients and Biotech Active Pharmaceutical Ingredients), Chemical Synthesis (Acetaminophen, Artemisinin, Saxagliptin, Sodium Chloride, Ibuprofen, Losartan Potassium, Enoxaparin Sodium, Rufinamide, Naproxen, Tamoxifen, Others), Type of Drug (Prescription Drugs, Over-the-Counter), Usage (Clinical, Research), Potency (Low-to-Moderate Potency Active Pharmaceutical Ingredients, Potent-to-Highly Potent Active Pharmaceutical Ingredient), Therapeutic Application (Cardiology, CNS and Neurology, Oncology, Orthopedic, Endocrinology, Pulmonology, Gastroenterology, Nephrology, Ophthalmology, Other Therapeutic Application) – Industry Trends and Forecast to 2029
Market Analysis and Size
According to the World Health Organization (WHO), cardiovascular diseases are the most significant cause of death worldwide, resulting in the deaths of 17.9 million people each year. The active pharmaceutical ingredient (API) is the substance that makes medicine work. API is a component of any medicine that generates the desired effects. Drugs are frequently made up of multiple ingredients. The API is the most important component. Excipients are other components that must be biologically innocuous and typically form a changing fraction of the medication composition. Formulation refers to optimizing and composing the mixture of components used in medicine.
Data Bridge Market Research analyses that the active pharmaceutical ingredients (API) market was valued at USD 61,553.13 million in 2021 and is expected to reach USD 111,423.24 million by 2029, registering a CAGR of 7.70% during the forecast period of 2022 to 2029. In addition to the market insights such as market value, growth rate, market segments, geographical coverage, market players, and market scenario, the market report curated by the Data Bridge Market Research team also includes in-depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.
Report Scope and Market Segmentation
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Report Metric
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Details
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Forecast Period
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2022 to 2029
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Base Year
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2021
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Historic Years
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2020 (Customizable to 2014 - 2019)
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Quantitative Units
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Revenue in USD Million, Volumes in Units, Pricing in USD
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Segments Covered
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Molecule (Small Molecule, Large Molecule), Type (Innovative Active Pharmaceutical Ingredients, Generic Innovative Active Pharmaceutical Ingredients), Type of Manufacturer (Captive API Manufacturer, Merchant API Manufacturer), Synthesis (Synthetic Active Pharmaceutical Ingredients and Biotech Active Pharmaceutical Ingredients), Chemical Synthesis (Acetaminophen, Artemisinin, Saxagliptin, Sodium Chloride, Ibuprofen, Losartan Potassium, Enoxaparin Sodium, Rufinamide, Naproxen, Tamoxifen, Others), Type of Drug (Prescription Drugs, Over-the-Counter), Usage (Clinical, Research), Potency (Low-to-Moderate Potency Active Pharmaceutical Ingredients, Potent-to-Highly Potent Active Pharmaceutical Ingredient), Therapeutic Application (Cardiology, CNS and Neurology, Oncology, Orthopedic, Endocrinology, Pulmonology, Gastroenterology, Nephrology, Ophthalmology, Other Therapeutic Application)
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Countries Covered
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U.S., Canada and Mexico
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Market Players Covered
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Dr. Reddy's Laboratories Ltd. (India), Sun Pharmaceutical Industries Ltd. (India), GlaxoSmithKline plc (U.K.), Pfizer Inc. (U.S.), Aurobindo Pharma (India), Sanofi (France), Lupin (India), Cipla Inc. (U.S.), BASF SE (Germany), Merck KGaA (Germany), Novo Nordisk A/S (Denmark), AbbVie Inc. (U.S.), Alembic Pharmaceuticals Limited (India), AstraZeneca (U.K.), Teva Pharmaceutical Industries Ltd. (Ireland), Alkem Labs (India), Saneca Pharmaceuticals (Slovakia), Jubilant Pharmova Limited (India), Neuland Laboratories Ltd (India)
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Market Opportunities
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Highly potent active pharmaceutical ingredients
Increase in the number of research and development activities
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Market Definition
The biological/synthetic active component of a final pharmaceutical product is an active pharmaceutical ingredient (API). Chemical synthesis, recombinant DNA, fermentation, isolation, and natural source recovery are popular API production methods. An API in a drug is used to treat, diagnose, mitigate, or prevent human health problems. It also directly influences the body's physiological functioning, restoring, correcting, or changing them. API has a wide range of applications in the pharmaceutical sector, including oncology, CNS diseases, diabetes, neurological disorders, cardiovascular and respiratory disorders, and others
North America Active Pharmaceutical Ingredients (API) Market Dynamics
Drivers
- Increasing prevalence of chronic diseases
The rising prevalence of chronic diseases such as Alzheimer's disease and others is estimated to enhance the growth of the active pharmaceutical ingredients (API) market. As per the Alzheimer's Association, 5.8 million people in the United States were living with Alzheimer's disease in 2020. This disease is the sixth biggest cause of death in the United States, and it is more common in persons over the age of 65. This number is likely to rise to 14 million as the baby-boomer generation reaches retirement age, aggravating the situation throughout the projection period. A new case of the disease is predicted to emerge every 33 seconds by 2050. ?
- Increasing investment for healthcare infrastructure
Another significant factor influencing the growth rate of active pharmaceutical ingredients (API) market is the rising healthcare expenditure which helps in improving its infrastructure. An increase in healthcare expenditure is being driven by an increase in the number of organizations conducting activities to raise awareness about hair regrowth and treatment alternatives.
Furthermore, rising initiatives by public and private organizations to spread awareness will expand the active pharmaceutical ingredients (API) market. Additionally, rising adoption rate of organ on chip models in drug development and rising focus on precision medicine will result in the expansion of active pharmaceutical ingredients (API) market.
Opportunities
- Increase in the number of research and development activities
Moreover, the market's growth is fueled by an increase in the number of research and development activities. This will provide beneficial opportunities for market growth of active pharmaceutical ingredients (API).
- Highly potent active pharmaceutical ingredients
HPAPIs (highly potent active pharmaceutical ingredients) mark a dramatic shift in how pharmaceutical companies use small molecules to offer new medicines. As a result of the change to HPAPIs, a pipeline of more effective drugs with lower doses has emerged. HPAPIs' advantages, such as their excellent efficacy, lower therapeutic dose required (due to their selective mode of action), and capacity to bind to specific receptors, can all be attributed to their growing popularity among producers and customers.
Moreover, rising investment for the development of advanced technologies and an increase in the number of emerging markets will provide beneficial opportunities for the active pharmaceutical ingredients (API) market growth during the forecast period.
Restraints/Challenges
On the other hand, high cost high cost associated with the production process will obstruct the growth rate of market. The dearth of skilled professionals and lack of healthcare infrastructure in developing economies will challenge the market's active pharmaceutical ingredients (API). Additionally, strict regulatory policies and the negative impact of COVID-19 on the supply chain will restrain and further impede the growth rate of the market during the forecast period of 2022-2029.
This North America active pharmaceutical ingredients (API) market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the active pharmaceutical ingredients (API) market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.
Patient Epidemiology Analysis
North America active pharmaceutical ingredients (API) market also provides you with detailed market analysis for patient analysis, prognosis and cures. Prevalence, incidence, mortality, adherence rates are some of the data variables that are available in the report. Direct or indirect impact analyses of epidemiology to market growth are analysed to create a more robust and cohort multivariate statistical model for forecasting the market in the growth period.
COVID-19 Impact on North America Active Pharmaceutical Ingredients (API) Market
The global increase in COVID-19 instances has influenced the development of active pharmaceutical ingredient producers over the projection period. In India's active pharmaceutical ingredient market, the government has finished a molecule-by-molecule charting of APIs supplied from China in order to boost domestic construction and imports from third-party providers in light of the COVID-19 pandemic's supply chain disruptions. The administration is organizing special provisions for APIs that must still be supplied from China.
The COVID-19 outbreak hampered several strategic pharmaceutical businesses' manufacturing and supply chains. The worldwide active pharmaceutical ingredient business model is expected to be impacted significantly by China's reliance on APIs for various biologics and generic pharmaceuticals. During the Chinese government's pandemic lockdown measures, around 44 enterprises were deemed invalid. This tendency has largely contributed to countries implementing local API manufacturing programs after re-evaluating their healthcare models in order to cure the infection and ensure a stable influx of API production.
North America Active Pharmaceutical Ingredients (API) Market Scope
The North America active pharmaceutical ingredients (API) market is segmented on the basis of drug type, indication, gender, diagnosis, route of administration, end-users and distribution channel. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.
Molecule
- Small Molecule
- Large Molecule
Type
- Innovative Active Pharmaceutical Ingredients
- Generic Innovative Active Pharmaceutical Ingredients
Type of Manufacturer
- Captive API Manufacturer
- Merchant API Manufacturer
Synthesis
- Synthetic Active Pharmaceutical Ingredients
- Biotech Active Pharmaceutical Ingredients
Chemical Synthesis
- Acetaminophen
- Artemisinin
- Saxagliptin
- Sodium Chloride
- Ibuprofen
- Losartan Potassium
- Enoxaparin Sodium
- Rufinamide
- Naproxen
- Tamoxifen
- Others
Type of Drug
- Prescription Drugs
- Over-the-Counter
Usage
- Clinical
- Research
Potency
- Low-to-Moderate Potency Active Pharmaceutical Ingredients
- Potent-to-Highly Potent Active Pharmaceutical Ingredient
Therapeutic Application
- Cardiology
- CNS and Neurology
- Oncology
- Orthopedic
- Endocrinology
- Pulmonology
- Gastroenterology
- Nephrology
- Ophthalmology
- Other Therapeutic Application
North America Active Pharmaceutical Ingredients (API) Market Regional Analysis/Insights
The North America active pharmaceutical ingredients (API) market is analysed and market size insights and trends are provided by country, drug type, indication, gender, diagnosis, route of administration, end-users and distribution channel as referenced above.
The countries covered in the North America active pharmaceutical ingredients (API) market report are U.S., Canada and Mexico.
The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of North America brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.
Competitive Landscape and North America Active Pharmaceutical Ingredients (API) Market Share Analysis
The North America active pharmaceutical ingredients (API) market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, North America presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to North America active pharmaceutical ingredients (API) market.
Some of the major players operating in the North America active pharmaceutical ingredients (API) market are:
- Dr. Reddy's Laboratories Ltd. (India)
- Sun Pharmaceutical Industries Ltd. (India)
- GlaxoSmithKline plc (U.K.)
- Pfizer Inc. (U.S.)
- Aurobindo Pharma (India)
- Sanofi (France)
- Lupin (India)
- Cipla Inc. (U.S.)
- BASF SE (Germany)
- Merck KGaA (Germany)
- Novo Nordisk A/S (Denmark)
- AbbVie Inc. (U.S.)
- Alembic Pharmaceuticals Limited (India)
- AstraZeneca (U.K.)
- Teva Pharmaceutical Industries Ltd. (Ireland)
- Alkem Labs (India)
- Saneca Pharmaceuticals (Slovakia)
- Jubilant Pharmova Limited (India)
- Neuland Laboratories Ltd (India)
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