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North America Gene Synthesis Market – Industry Trends and Forecast to 2029

Healthcare

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North America Gene Synthesis Market – Industry Trends and Forecast to 2029

  • Healthcare
  • Published Report
  • Dec 2022
  • North America
  • 350 Pages
  • No of Tables: 60
  • No of Figures: 49

North America Gene Synthesis Market – Industry Trends and Forecast to 2029

Market Size in USD Billion

CAGR :  % Diagram

Diagram Forecast Period 2021–2029
Diagram Market Size (Base Year) USD 720.79 USD Million
Diagram Market Size (Forecast Year) USD 3,943.72 USD Million
Diagram CAGR %

Major Markets Players

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North America Gene Synthesis Market, By Component (Synthesizer, Consumables, and Software & Services),  Gene Type (Standard Gene, Express Gene, Complex Gene and Others), Gene Synthesis Type (Gene Library Synthesis and Custom Gene Synthesis), Application (Synthetic Biology, Genetic Engineering, Vaccine Design, Therapeutics Antibodies, and Others), Method  (Solid Phase Synthesis, Chip-Based, DNA Synthesis, and PCR-Based Enzyme Synthesis), End User (Academic & Research Institutes, Diagnostics Laboratories, Biotech & Pharmaceutical Companies, and Others) Distribution Channel (Direct Tender, Online Distributions, and Third Party Distributions) Industry Trends and Forecast to 2029.

North America Gene Synthesis Market

North America Gene Synthesis Market Analysis and Insights 

Gene synthesis is the process of creating artificial genes in a lab setting using synthetic biology. The generation of recombinant proteins is one of the numerous applications of recombinant DNA technology, where gene synthesis is emerging as a key instrument. The traditional methods of cloning and mutagenesis are quickly being replaced by de novo gene synthesis, which also enables the production of nucleic acids for which there is no template.

North America Gene Synthesis Market

North America Gene Synthesis Market

North America gene synthesis market is expected to grow in the forecast period of 2022 to 2029. Data Bridge Market Research analyses that the market is growing with a CAGR of 23.4% in the forecast period of 2022 to 2029 and is expected to reach USD 3,943.72 million by 2029 from USD 720.79 million in 2021.

Report Metric

Details

Forecast Period

2022 to 2029

Base Year

2021

Historic Years

2020 (Customizable to 2019-2015)

Quantitative Units

Revenue in USD Million

Segments Covered

By Component (Synthesizer, Consumables, and Software & Services),  Gene Type (Standard Gene, Express Gene, Complex Gene and Others), Gene Synthesis Type (Gene Library Synthesis and Custom Gene Synthesis), Application (Synthetic Biology, Genetic Engineering, Vaccine Design, Therapeutics Antibodies, and Others), Method  (Solid Phase Synthesis, Chip-Based, DNA Synthesis, and PCR-Based Enzyme Synthesis), End User (Academic & Research Institutes, Diagnostics Laboratories, Biotech & Pharmaceutical Companies, and Others) Distribution Channel (Direct Tender, Online Distributions, and Third Party Distributions).

Countries Covered

U.S., Canada, and Mexico

Market Players Covered

Twist Bioscience, OriGene Technologies, Integrated DNA Technologies, Inc. 9Subsidiary of Danaher Corporation), Ansa Biotechnologies, Inc., Thermo Fisher Scientific, Genescript, Synbio Technologies, Proteogenix, Bio Basic Inc., Ginkgo Bioworks, Evonetix, ProMab Biotechnologies, Inc., Azenta US, Inc., and others.

MARKET DEFINITION

Gene synthesis refers to the chemical synthesis of DNA strands base by base. Unlike DNA replication that occurs in cells or by Polymerase Chain Reaction (PCR), gene synthesis does not require a template strand. Rather, gene synthesis involves the step-wise addition of nucleotides to a single-stranded molecule, which then serves as a template for creating a complementary strand. Gene synthesis is the fundamental technology upon which synthetic biology has been built.

Gene Synthesis Market Dynamics

This section deals with understanding the market drivers, opportunities, restraints, and challenges. All of this is discussed in detail below:

Drivers

  • INCREASED PREVALENCE OF CHRONIC INFECTIOUS DISEASES

Bacterial and viral diseases are rapidly expanding due to the rising prevalence of infectious diseases worldwide. As a result, the demand for novel and effective therapies has increased to fight against such deadly diseases. These diseases can be cured using chemical drugs and biological therapies, including gene therapy. Applying genomics has enhanced the management of infectious and endemic diseases. It also allows us to understand emerging drug resistance and identify targets for new therapeutics and vaccines. For the treatment of infectious diseases, gene therapy has attracted many researchers as it can be treated by using recombinant DNA technology, DNA & RNA ribozyme, and single-chain antibodies.

As the rising prevalence of the chronic infectious disease is increasing globally, the demand for vaccines and effective gene therapy has also risen, increasing the demand for novel genes with a significant application for research activities and drug and vaccine manufacturing. Thus, the rising prevalence of infectious diseases is driving the gene synthesis market growth.

  • RISING ADOPTION OF GENE THERAPY

Gene therapy is an advanced technique that includes using several genes to prevent a particular disease type. The technique involves the insertion of genes into patient cells instead of drugs and surgery. Due to increased demand for novel and long-lasting therapy results, the adoption of gene therapy is rising. Gene therapies demand synthetic gene constructs, among other gene products, to accelerate gene therapy development. Due to the rise in genetic diseases, the demand for a proper cure is one major factor, and with the help of gene therapy, a particular disease type can be cured.

Due to the increased demand, leaders constantly focus on producing gene therapy products, achieving approval, and marketing authorizations.

Lifesaving medicines and therapies are in huge demand to provide quality life to patients. These rising numbers of patients largely depend upon the gene therapies available to achieve a proper cure. To manufacture gene therapies, synthetic and novel genes are required, which can be achieved by the gene synthesis technique. Thus, the rising adoption of gene therapy is expected to act as a driver for the gene synthesis market.

  • EXPANSION OF SYNTHETIC BIOLOGY

The incorporation of engineering principles into biology is termed synthetic biology. DNA genome can be reassembled with the help of synthetic biology as it involves the chemical synthesis of DNA by combining it with its genome. Oligonucleotides can be constructed in a short period by incorporating the usage of gene synthesis services, software, and consumables. As synthetic biology products' demand increases worldwide, gene synthesis products and services are also increasing.

Thus, due to its effective and innovative products, the demand for synthetic biology products is increasing globally, which is expected to act as a driving factor for the gene synthesis market.

North America Gene Synthesis Market

Opportunity

  •   RISE IN HEALTHCARE EXPENDITURE

Healthcare expenditure has increased worldwide as people's disposable income in various countries increases. Moreover, to accomplish the population requirements, government bodies and healthcare organizations are taking the initiative by accelerating healthcare expenditure.

Also, the strategic initiatives key market players take will provide structural integrity and future opportunities for the medical device testing market in the forecast period of 2022-2029.

Restraints/Challenges

  • Technical limitations across production process

However, the barriers to the gene synthesis techniques and the high cost of the gene synthesis process in some regions may impede the growth of the gene synthesis procedures hampering the market's growth. Additionally, high competition in medical technology industries and long lead time for overseas qualification can be challenging factors for the growth of the market

This gene synthesis market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, the impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market

Recent Development

  • In December 2020, Twist Bioscience launched clonal-ready gene fragments to complete the offering of genes. The fragments launched can be used with or without adapters to build the perfect clones. The clonal-ready gene fragments are compatible with the protein expression pathways, enzyme engineering, and gene expression, among others.
  • In 2020, according to an article published in an ACS journal, an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths were reported worldwide. This suggests that cancer coverage is suboptimal, and there is a great need to implement high coverage worldwide

North America Gene Synthesis Market Scope

North America gene synthesis market is segmented into components, gene type, gene synthesis type, application, method, end user, and distribution channel. The growth amongst these segments will help you analyze meager growth segments in the industries and provide the users with a valuable market overview and market insights to make strategic decisions to identify core market applications.

Components

  • Synthesizers
  • Consumables
  • Software & services

On the basis of components, the North America gene synthesis market is segmented into synthesizers, consumables, and software & services.

Gene Type

  • Standard gene
  • Express gene
  • Complex gene
  • Others

On the basis of gene type, the North America gene synthesis market is segmented into the standard gene, express gene, and complex gene, Others.

Gene Synthesis Type

  • Gene library synthesis
  • Custom gene synthesis

On the basis of gene synthesis type, the North America gene synthesis market is segmented into gene synthesis library and custom gene synthesis.

Application

  • Synthetic biology,
  • Genetic engineering,
  • Vaccine design,
  • Therapeutics antibodies 
  • Others

On the basis of application, the North America gene synthesis market is segmented into synthetic biology, genetic engineering, vaccine design, therapeutics antibodies, and others.

Method

  • Solid phase synthesis,
  • Chip-based DNA synthesis
  • Pcr-based enzyme synthesis

On the basis of method, the North America gene synthesis market is segmented into solid phase synthesis, chip-based DNA synthesis, and PCR-based enzyme synthesis.

End User

  • Academic & research institutes,
  • Diagnostics laboratories,
  • Biotech & pharmaceutical companies 
  • Others

On the basis of end user, the North America gene synthesis market is segmented into academic & research institutes, diagnostics laboratories, biotech & pharmaceutical companies, and others.

Distribution Channel

  • Direct tender
  • Online Distribution
  • Third Party Distributors

On the basis of distribution channel, the North America gene synthesis market is segmented into direct tender, online distribution, and third party distributors.

North America Gene Synthesis Market

Gene Synthesis Market Regional Analysis/Insights               

The gene synthesis market is analyzed, and market size insights and trends are provided by the country, component, gene type, gene synthesis type, application, method, end user, and distribution channel, as referenced above.

The U.S. dominates the North American gene synthesis market in terms of market share and market revenue and will continue to flourish dominance during the forecast period. This is due to the rising need for verifying and validating gene synthesis processes in the region, and rapid research development is boosting the market.

The country section of the report also provides individual market-impacting factors and changes in regulations in the market that impact the current and future trends of the market. Data points, such as new and replacement sales, country demographics, disease epidemiology, and import-export tariffs, are some of the major pointers used to forecast the market scenario for individual countries. In addition, the presence and availability of global brands and their challenges faced due to high competition from local and domestic brands and the impact of sales channels are considered while providing forecast analysis of the country data.

Competitive Landscape and Gene Synthesis Market Share Analysis

The gene synthesis market competitive landscape provides details of the competitors. Details include company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, and application dominance. The above data points are only related to the companies focusing on the ataxia market.

Some of the major players operating in the gene synthesis market are ATDBio Ltd (Subsidiary of Biotage), General Biosystems, Inc., MACROGEN CO., LTD., Boster Biological Technology, Creative Biogene, Bioneer Pacific, exonbio, trenzyme GmbH, Twist Bioscience, BioCat GmbH (Subsidiary of AddLife AB), OriGene Technologies, Inc., Integrated DNA Technologies, Inc. 9Subsidiary of Danaher Corporation), Eurofins Scientific, NZYTech, Lda. - Genes and Enzymes, Ansa Biotechnologies, Inc., Thermo Fisher Scientific, Genescript, Synbio Technologies, Proteogenix, Bio Basic Inc., ATG: biosynthetic GmbH, Merck KGaA, Kaneka Eurogentec S.A, Ginkgo Bioworks, Bbi-lifesciences, Evonetix, ProMab Biotechnologies, Inc., GCC Biotech (INDIA) Pvt. Ltd., CSBio, Azenta US, Inc., and among others.


SKU-

TABLE 1 NORTH AMERICA GENE SYNTHESIS MARKET, BY COMPONENT, 2020-2029 (USD MILLION)

TABLE 2 NORTH AMERICA CONSUMABLES IN GENE SYNTHESIS MARKET, BY TYPE, 2020-2029 (USD MILLION)

TABLE 3 NORTH AMERICA SYNTHESIZER IN GENE SYNTHESIS MARKET, BY TYPE, 2020-2029 (USD MILLION)

TABLE 4 NORTH AMERICA GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 5 NORTH AMERICA GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 6 NORTH AMERICA CUSTOM GENE SYNTHESIS IN GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 7 NORTH AMERICA GENE LIBRARY SYNTHESIS IN GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 8 NORTH AMERICA GENE SYNTHESIS MARKET, BY APPLICATION, 2020-2029 (USD MILLION)

TABLE 9 NORTH AMERICA SYNTHETIC BIOLOGY IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 10 NORTH AMERICA GENETIC ENGINEERING IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 11 NORTH AMERICA THERAPEUTIC ANTIBODIES IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 12 NORTH AMERICA VACCINE DESIGN IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 13 NORTH AMERICA GENE SYNTHESIS MARKET, BY METHOD, 2020-2029 (USD MILLION)

TABLE 14 NORTH AMERICA GENE SYNTHESIS MARKET, BY END USER, 2020-2029 (USD MILLION)

TABLE 15 NORTH AMERICA GENE SYNTHESIS MARKET, BY DISTRIBUTION CHANNEL, 2020-2029 (USD MILLION)

TABLE 16 U.S. GENE SYNTHESIS MARKET, BY COMPONENT, 2020-2029 (USD MILLION)

TABLE 17 U.S. CONSUMABLES IN GENE SYNTHESIS MARKET, BY TYPE, 2020-2029 (USD MILLION)

TABLE 18 U.S. SYNTHESIZER IN GENE SYNTHESIS MARKET, BY TYPE, 2020-2029 (USD MILLION)

TABLE 19 U.S. GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 20 U.S. GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 21 U.S. CUSTOM GENE SYNTHESIS IN GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 22 U.S. GENE LIBRARY SYNTHESIS IN GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 23 U.S. GENE SYNTHESIS MARKET, BY APPLICATION, 2020-2029 (USD MILLION)

TABLE 24 U.S. SYNTHETIC BIOLOGY IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 25 U.S. GENETIC ENGINEERING IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 26 U.S. THERAPEUTIC ANTIBODIES IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 27 U.S. VACCINE DESIGN IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 28 U.S. GENE SYNTHESIS MARKET, BY METHOD, 2020-2029 (USD MILLION)

TABLE 29 U.S. GENE SYNTHESIS MARKET, BY END USER, 2020-2029 (USD MILLION)

TABLE 30 U.S. GENE SYNTHESIS MARKET, BY DISTRIBUTION CHANNEL, 2020-2029 (USD MILLION)

TABLE 31 CANADA GENE SYNTHESIS MARKET, BY COMPONENT, 2020-2029 (USD MILLION)

TABLE 32 CANADA CONSUMABLES IN GENE SYNTHESIS MARKET, BY TYPE, 2020-2029 (USD MILLION)

TABLE 33 CANADA SYNTHESIZER IN GENE SYNTHESIS MARKET, BY TYPE, 2020-2029 (USD MILLION)

TABLE 34 CANADA GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 35 CANADA GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 36 CANADA CUSTOM GENE SYNTHESIS IN GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 37 CANADA GENE LIBRARY SYNTHESIS IN GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 38 CANADA GENE SYNTHESIS MARKET, BY APPLICATION, 2020-2029 (USD MILLION)

TABLE 39 CANADA SYNTHETIC BIOLOGY IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 40 CANADA GENETIC ENGINEERING IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 41 CANADA THERAPEUTIC ANTIBODIES IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 42 CANADA VACCINE DESIGN IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 43 CANADA GENE SYNTHESIS MARKET, BY METHOD, 2020-2029 (USD MILLION)

TABLE 44 CANADA GENE SYNTHESIS MARKET, BY END USER, 2020-2029 (USD MILLION)

TABLE 45 CANADA GENE SYNTHESIS MARKET, BY DISTRIBUTION CHANNEL, 2020-2029 (USD MILLION)

TABLE 46 MEXICO GENE SYNTHESIS MARKET, BY COMPONENT, 2020-2029 (USD MILLION)

TABLE 47 MEXICO CONSUMABLES IN GENE SYNTHESIS MARKET, BY TYPE, 2020-2029 (USD MILLION)

TABLE 48 MEXICO SYNTHESIZER IN GENE SYNTHESIS MARKET, BY TYPE, 2020-2029 (USD MILLION)

TABLE 49 MEXICO GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 50 MEXICO GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 51 MEXICO CUSTOM GENE SYNTHESIS IN GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 52 MEXICO GENE LIBRARY SYNTHESIS IN GENE SYNTHESIS MARKET, BY GENE TYPE, 2020-2029 (USD MILLION)

TABLE 53 MEXICO GENE SYNTHESIS MARKET, BY APPLICATION, 2020-2029 (USD MILLION)

TABLE 54 MEXICO SYNTHETIC BIOLOGY IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 55 MEXICO GENETIC ENGINEERING IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 56 MEXICO THERAPEUTIC ANTIBODIES IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 57 MEXICO VACCINE DESIGN IN GENE SYNTHESIS MARKET, BY GENE SYNTHESIS TYPE, 2020-2029 (USD MILLION)

TABLE 58 MEXICO GENE SYNTHESIS MARKET, BY METHOD, 2020-2029 (USD MILLION)

TABLE 59 MEXICO GENE SYNTHESIS MARKET, BY END USER, 2020-2029 (USD MILLION)

TABLE 60 MEXICO GENE SYNTHESIS MARKET, BY DISTRIBUTION CHANNEL, 2020-2029 (USD MILLION)

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The North America Gene Synthesis Market is projected to grow at a CAGR of 23.4% during the forecast period by 2029.
The future market value of the North America Gene Synthesis Market is expected to reach USD 3,943.72 million by 2029.
The major players in the North America Gene Synthesis Market are Twist Bioscience, OriGene Technologies, Integrated DNA Technologies, Inc. 9Subsidiary of Danaher Corporation), Ansa Biotechnologies, Inc., Thermo Fisher Scientific, Genescript, etc.
The countries covered in the North America Gene Synthesis Market are U.S., Canada, and Mexico.
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