Global Foot And Ankle Allograft Market According to Data Bridge Market Research new Market report, By Product Type(Allograft Wedges, Allograft Tendons, Allograft Acellular Dermal Matrix, Cartilage Allograft Matrix, Skin Allografts, Amniotic Membranes), By Surgery type( arthrodesis Procedures, Osteotomy Procedures, Others), End user (Hospitals, Orthopedic Clinics, Ambulatory Center), By Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa) - Industry Trends and Forecast is projected to reach USD 5.1 billion by 2025, at a CAGR of 4.8% during the forecast period of 2018 to 2025. Hospital segment is expected to dominate the market with a share of 56.3% and is expected to reach USD 228.98 million by 2025 from USD 153.21 million in 2016 growing at the highest CAGR of 3.5% in the forecast period 2018 to 2025.
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Allografts are mostly used during reconstructive procedures around the foot and ankle. As compare with autograft tissue, allografts offer the advantages of unlimited tissue sources, decrease operative time, and lack of potential donors-site morbidity, Allografts can be classified in to broad categories (1) Osteochondral grafts. (2) Osseous/structural grafts, and (3) Allograft tendons .The use of these grafts has increased dramatically in the past decade, but there is concern that enthusiasm surroundings their use has outspaced the published supporting their efficacy and safety. The major factors driving the growth of this market are the increasing numbers of sports injuries, increasing number of arthroscopic surgeries, technological advancement & new product launches, rising number of aging and geriatric population, and increasing incidence of chronic wounds and diabetic foot ulcer. On the other hand, lack of formal education and training may hinder the growth of the market in U.S. Allografts are used in various procedures like joint reconstruction in the knee and ankle, ACL repair, reconstruction due to cancer or trauma, urological procedures, spinal fusion, shoulder repair.
Amniotic membranes and skin allografts are majorly used to treat ankle ulcer and neuropathic foot ulcer.
Bone graft is a common adjunct procedure in orthopedic surgery used for fusions, fracture repair, and the reconstruction of skeletal defects in the foot and ankle. Autologous graft, or autograft, involves the transport of bone from a donor site to another location in the same patient. It is considered by many to be the gold standard of bone grafting, as it is provides all biologic factors required for functional graft. Further, autograft is 100% histocompatible with no risk of disease transmission.
Allografts have several important advantages over other forms of bone graft augmentation. In addition to preventing the morbidity of autogenous bone graft harvesting, the quantity of allograft bone is essentially unlimited and is therefore valuable for use in treating very large defects that exceed the yield of the iliac crest. Allografts are particularly helpful in obese patients or patients with systemic disease because the they has the potential to reduce blood loss and anesthesia time .
One of the major application of Dehydrated amniotic-derived tissue allograft is its use in Diabetic Foot Ulcers. DAMA(dehydrated amniotic-derived tissue allograft) was applied by trimming it to fit of the wound (~1mm overlap of wound margins) under disinfected conditions. DAMA was permitted to self-adhere and was then covered using non-adherent contact layer,protected with retention tape and then covered with foam dressing. The number of DAMA applications and time between DAMA applications was based on the physician’s judgment of need for additional applications.
The global market for foot and ankle allograft by the following sub-categories is presented
Some of the major factors driving the market for global foot and ankle allograft market are:
Increasing numbers of sports injuries:
In the U.S., about 30 million children and teens participate in some form of organized sports, and more than 3.5 million injuries each year, which cause some loss of time of participation, are experienced by the participants. Almost one-third of all injuries incurred in childhood are sports-related injuries. By far, the most common injuries are sprains and strains.
Few sports are more dangerous than others, such as contact sports including football can be expected to result in a higher number of injuries than a non-contact sport such as swimming. However, all types of sports have a potential for injury, whether from the trauma of contact with other players or from overuse or misuse of a body part.
Below are few statistics mentioned in National SAFE KIDS Campaign and the American Academy of Pediatrics:
Ankle sprains account for the half of the sports injuries. As per American College of Sports Medicine (ACSM), 2013, each day 25,000 Americans suffer from an ankle sprain. In this, 80.0% of ankle sprains are due to inward rolling or inversion of the ankle.
More than 775,000 children, ages 14 and younger, are treated in hospital emergency rooms for sports-related injuries each year. Most of the injuries occurred as a result of falls, being struck by an object, collisions, and overexertion during unorganized or informal sports activities. Sporting injuries around the ankle vary from simple sprains that will resolve spontaneously within a few days to severe injuries which may never fully recover and may threaten the career of a professional athlete. Some of these injuries can be easily overlooked altogether or misdiagnosed with potentially devastating effects on future performance
Rising number of aging and geriatric population:
According to the Global Health and Aging report presented by the World Health Organization (WHO), the number of people aged 65 or older are projected to grow from an estimated 524 million in 2010 to about 1.5 billion in 2050, with most of the increase in developing countries. There are certain health conditions that are expected to be a challenge to our health care system with the increasing aging population. These conditions include cancer, dementia, increase in the number of falls, obesity, and diabetes.
The world’s older population continues to grow at an unprecedented rate. Today, 8.5% of people worldwide (617 million) are aged 65 and over.
At present, 8% of the world population is over 65 years of age, and this percentage is expected to increase to 20% in 20 years, with many of these people being older than 80. For example, it is estimated that in Italy there will be more than one million people over 90 in the year 2024 and, in China, it is estimated that 330 million people will be older than 65 and 100 million will be older than 80 in 2050. The growth of the elderly population is considered a global phenomenon.
These factors increase the demand for products such as allograft wedges, allograft tendons, allograft acellular dermal matrix, cartilage allograft matrix, skin allografts and amniotic membrane. Allografts are used in various procedures like joint reconstruction in the knee and ankle, ACL repair, reconstruction due to cancer or trauma, urological procedures, spinal fusion, shoulder repair. Amniotic membranes and skin allografts are majorly used to treat ankle ulcer and neuropathic foot ulcer.
Some of the major market players in foot and allograft market are, CONMED Corporation, Wright Medical Group N.V., AlloSource, Amniox Medical, Inc., Bone Bank Allografts, RTI Surgical, Inc., Zimmer Biomet, Arthrex, Inc.,JRF Ortho,Musculoskeletal Transplant Foundation ,Integra Life Sciences Corporation, Lattice Biologics Ltd., Smith & Nephew plc, Tornier N.V. (Netherlands), Össur (Iceland), Acumed, LLC (U.S.), and Extremity Medical, LLC (U.S.).
Global foot and ankle allograft market is dominated by CONMED Corporation, followed by Wright Medical Group N.V. and RTI Surgical, Inc. The foot and ankle allograft market in the global region is leading in North America, Europe, Asia-Pacific, South America and Middle East and Africa. North America accounts for the highest market share in this region. Allograft acellular dermal matrix segment is expected to dominate the global foot and ankle allograft market.
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