In 2021, IgG4-Related Dacryoadenitis and Sialadenitis Segment is Expected to Dominate the Global IgG4-Related Disease Market with 33.27% Market Share

In Japan, the prevalence of the disease has been reported to be approximately 0.28 to 1.08 per 100,000 of population. IgG4-RD cohorts generally have a slight predominance of middle-aged and older men. The predilection for older men is certainly true for conditions such as type 1 (IgG4-related) autoimmune pancreatitis (AIP), retroperitoneal fibrosis, IgG4-related tubulointerstitial nephritis (TIN), and many other organ manifestations. However, the sex distribution differs somewhat about patients with head and neck involvement. In a prospective study of 403 IgG4-RD patients, sialadenitis, dacryoadenitis, and thyroiditis were more common in women. The disease is also increasingly recognized to occur in children.

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Global IgG4-related disease market is expected to reach USD 4,260.08 million by 2028 from USD    3230.75 million in 2020, growing at a substantial CAGR of 3.9% in the forecast period of 2021 to 2028. The increased research and development investment for drug discovery and increasing health expenditure have accelerated the need for drugs in healthcare facilities. The surging volume of IgG4-related disease patients and the rising prevalence of IgG4-related diseases are also propelling the market's growth. 

High prevalence of immunoglobulin G4-related disease (IGG4-RD) will drive the market's growth rate

Autoimmune pancreatitis (Type 1 ) (IgG4-related) AIP is the prototypical form of IgG4-RD. The prevalence of autoimmune pancreatitis (Type 1 ) (IgG4-related) AIP, which is a prototypical form of IgG4-RD in Japan, has been estimated to be 0.82 per 100,000 persons. It is also reported that an increased standardized prevalence ration of malignancy history in IgG4-RD patients5, while studies from Asia, Europe, and America have also suggested an increased standardized incidence ratio of malignancy in patients with IgG4-RD. This is driving the growth of the market. Increased expenditure by public and private players on infrastructure development will also promote the market growth rate. Continuous research and development pertaining to the deployment of advanced technologies will yet again widen the scope of growth.  

Report Scope and Market Segmentation

Segment Analysis:

Global IgG4-related disease market  is categorized into five notable segments which are based on disease type, type, route of administration, end user, and distribution channel

• On the basis of disease type, the global IgG4-related disease market is segmented into type 1 (IgG4-related) autoimmune pancreatitis (AIP), retroperitoneal fibrosis, IgG4-related tubulointerstitial nephritis (tin), IgG4-related sclerosing cholangitis IgG4-related dacryoadenitis and sialadenitis, IgG4-related pachymeningitis, IgG4-related thyroid disease, serum IgG4 concentration and others. In 2021, IgG4-related dacryoadenitis and sialadenitis segment is expected to dominate the global IgG4-related disease market  with 33.27% market share due to increasing prevalence of this disease type among target population.
• On the basis of type, the global IgG4-related disease market is segmented into diagnostic and treatment. In 2021, diagnostic segment is expected to dominate the global IgG4-related disease market  with 64.61% market share because of rising incidence of IgG4-related disease and increasing healthcare expenditure.
• On the basis of route of administration, the gobal IgG4-related disease market is segmented into oral, parenteral and others. In 2021, parenteral segment is expected to dominate the global IgG4-related disease market  with 56.79% market share because it is most effective mode administration with better patient compliance.
• On the basis of end user, the global IgG4-related disease market is segmented into hospitals, specialty clinics, home healthcare, others. In 2021, hospitals segment is expected to dominate the global IgG4-related disease market  with 65.09% market share because of surging pool of IgG4-related disease patients.

The hospitals segment will dominate the end-user segment of the IgG4-related disease market

The hospitals segment will emerge as the dominating segment under end-user in 2021 with approximately 65% market share. This is because of the growing number of infrastructural development activities in the market especially in the developing economies. Further, growth and expansion of the healthcare industry all around the globe will further bolster the growth of this segment.

• On the basis of distribution channel, the global IgG4-related disease market is segmented hospital pharmacy, retail pharmacy, online pharmacy and others. In 2021, the hospital pharmacy segment is expected to dominate the global IgG4-related disease market  with 53.51% market share owing to the rising among the target population and increasing R & D activities.

The hospital pharmacy segment will dominate the distribution channel segment of the IgG4-related disease market

The hospital pharmacy segment will emerge as the dominating segment under distribution channel segment in 2021. This is because of the growing number of hospital pharmacies in the market especially in the developing economies. Further, growth and expansion of research development services on a global scale will further bolster the growth of this segment.

Major Players              

Data Bridge Market Research recognizes the following companies as the market players in distributed energy resources management system (DERMS)  market: Zydus Cadila (India), Hikma Pharmaceuticals PLC (U.K.), Lannett (U.S.), Sun Pharmaceutical Industries Ltd. (India), Baxter (U.S.),  Viatris Inc. (U.S.),  Amgen Inc. (U.S.), Sandoz International GmbH  (Germany), Fresenius Kabi USA (U.S.), Pfizer Inc. (U.S.), Cipla Inc. (U.S.), Celltrion Healthcare Co., Ltd. (South Korea), and ANI Pharmaceuticals, Inc. (U.S.).

Market Development

• A definitive deal was struck in September 2021 by ANI Pharmaceuticals, Inc. to buy privately held Novitium Pharma, a pharmaceutical business with development, production, and commercialization capabilities, for $163.5 million. This deal is anticipated to increase the company's product sales in the market over the next few years.  

Regional Analysis

Geographically, the countries covered in the IgG4-related disease market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

As per Data Bridge Market Research analysis:

North America is the dominant region in IgG4-related disease market during the forecast period 2021 - 2028

Due to the region's rapid technological development, North America is predicted to lead the global IgG4-related disease market. Due to growing public awareness of IgG4-related sickness, the U.S. controls the market and is driving growth in this sector.

Asia-Pacific is estimated to be the fastest-growing region in IgG4-related disease market the forecast period 2021 - 2028

Due to rising healthcare costs in the area, Asia-Pacific is anticipated to see the greatest CAGR during the projection period. Due to its growing middle class, China is the market leader in the Asia-Pacific region.

COVID-19 Impact

The COVID-19 pandemic has greatly shifted the healthcare resources towards meeting the demands arising out of COVID-19 emergencies. This has therefore, impacted the market adversely. Non-essential healthcare processes and procedures were halted during this period, creating a sense of adversity among the patients. However, with the economies reviving out of the pandemic, they market is set to bounce back.

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