Europe Long Read Sequencing Market – Industry Trends and Forecast to 2030

Europe Long Read Sequencing Market, By Technology (Single-Molecule Real-Time Sequencing, Nanopore Sequencing, Synthetic Long Read Sequencing, and Others), Product (Instruments, Consumables, and Services), Application (Whole Genome Sequencing, Epigenetics, RNA Sequencing, Complex Population, Targeted Sequencing, Identification and fine mapping of structural variation, Tandem Repeat Sequencing, Pseudogene discrimination, Resolving allele phasing, Reproductive genomics, Cancer, Viral and Microbial Sequencing and Others), Workflow (Pre-Sequencing, Sequencing, and Data Analysis), End-user (Academic and Research Institutes, Clinical Laboratories, Hospitals, Pharma and Biotech Entities, and Others) – Industry Trends and Forecast to 2030.

Europe Long Read Sequencing Market Analysis and Size

According to the World Health Organization (WHO), around 72,000 newborn babies are affected by sickle cell anaemia, a severe genetic disorder. Hemophilia, a genetic bleeding disorder, has also affected over 6000 people in the United Kingdom. Furthermore, alpha and beta-thalassemia are the most common inherited single gene affected genetic disorders in the world, accounting for the majority of cases. The burden of this disorder is high, such as in Iran, where the WHO estimates that approximately 8,000 pregnancies are at risk of the disease each year. Additionally, other genetic diseases such as colour blindness, Down syndrome, cystic fibrosis, and frequent incidences of DNA, RNA, and protein synthesis disorders are expected to drive the growth of the long-read sequencing market as demand for early diagnosis grows.

Data Bridge Market Research analyses that the long read sequencing market, which was USD 515.64 million in 2022, would be up to USD 2514.06 million by 2030 and is expected to undergo a CAGR of 21.9% during the forecast period 2023-2030. In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework

Europe Long Read Sequencing Market Scope and Segmentation

Market Definition

Long-read sequencing, also known as third-generation sequencing, is a technique for large-scale data analysis. This is a technology in which DNA particles are sequenced in real-time, and long reads are produced as a result of this straight sequencing. Frequently, these sequencing reactions are approved without the use of PCR amplification. Long-read sequencing techniques include single molecule real-time (SMRT) and nanopore sequencing.

Europe Long Read Sequencing Market Dynamics

Drivers

• The surge in incidences of genetic disorders

The growing number of entities affected by genetic disorders will contribute to market growth in the coming years. According to the Centers for Disease Control and Prevention, there are approximately 100,000 sickle cell disease patients in the United States. The advancement of patients will pique the interest of many key companies, which is expected to propel the market's growth.

• Rising use of long-read sequencing

Long-read sequencing has numerous advantages over short or second-generation sequencing techniques, which is fuelling market growth even further. For instance, long reads generated by single-molecule real-time sequencing (SMRT) provide a comprehensive overview of the entire genome and are used to detect various genetic and structural variants. Long-read sequencing, researchers estimated in 2015, could be used to assemble dozens of bacterial and viral genomes. Aside from that, increased R&D investments and rising awareness of long read sequencing drive market growth.

Opportunities

• Rising utilization of sequence analysis methodologies

One of the key factors driving market growth is the growing acceptance of modern medical diagnostic approaches. LRS technology's growing popularity is also due to its portability and real-time speed. It is also used to generate an accurate reference map of the centromeres on the chromosomes. In addition, several biotech companies are working on novel technologies that combine a new library prep method with genome analysis tools. Several studies have demonstrated that LRS technology is critical for identifying novel pathogenic mutations in human diseases with unknown genetic causes. This provides numerous opportunities for researchers to use the technology in whole-genome sequencing (WGS), allowing medical genetics to progress.

Restraints/Challenges

• Higher cost per base relative to short-read sequencing

Long-read sequencing market is facing trials due to the lack of highly cutting-edge genomic testing centers, expensive installation processes, and the absence of experts specific with progressive diagnostic abilities.

This long read sequencing market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the long read sequencing market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

Recent Development

• In 2019, Oxford Nanopore created Flongle to quickly analyse short DNA/RNA sequences. Flongle is a GridION X5 desktop and MinION portable sequencing adaptor. Small Flange cells with up to 1.8 Gb of sequence data capacity and headroom for up to 3 Gb. This merchandise promotion will help the company's product portfolio to be more consolidated.
• In 2020, Promega Corporation launched the Wizard HMW DNA Extraction Kit for scientists working with large genomic DNA fragments. Using this kit, researchers can obtain DNA fragments that will improve performance in long read sequencing applications in 90 minutes. As a result, the company's product portfolio has become more appealing, appealing, and advanced.

Europe Long Read Sequencing Market Scope

The long read sequencing market is segmented on the basis of technology, product, workflow, application and end-user. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Technology

• Nanopore Sequencing
• Single Molecule Real Time Sequencing (SMRT)

Product

• Consumables
• Instruments

Type

• System
• Software
• Services

Workflow

• Sequencing
• Data Analysis
• Pre-Sequencing

Application

• Whole Genome Sequencing
• Epigenetics
• RNA Sequencing
• Complex Population
• Tandem Repeat Sequencing

• Identification and fine mapping of structural variation
• Viral and Microbial Sequencing
• Reproductive genomics
• Pseudogene discrimination
• Others

End User

• Hospitals and Clinics
• Pharmaceutical and Biotechnology Industry
• Others

Long Read Sequencing Market Regional Analysis/Insights

The long read sequencing market is analyzed and market size insights and trends are provided by country, technology, product, workflow, application and end-user as referenced above.

The countries covered in the long read sequencing market report are Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe.

Germany is dominating the long read sequencing market due to the large number of companies and the increasing adoption of next generation sequencing for clinical diagnostics.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.   

Competitive Landscape and Long Read Sequencing Market Share Analysis

The long read sequencing market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to long read sequencing market.

Some of the major players operating in the long read sequencing market are:

• Illumina, Inc. (U.S.)
• MicrobesNG (U.S.)
• Roche Sequencing (U.S.)
• F. Hoffmann-La Roche Ltd. (Switzerland)
• PacBio (U.S.)
• Oxford Nanopore Technologies plc (U.K.)
• Quantapore, Inc. (U.S.)
• FG Technologies (Switzerland)
• BaseClear B.V (Netherlands)
• INSTITUTE OF INTEGRATIVE CELL BIOLOGY AND PHYSIOLOGY (France)
• The Garvan Institute (Australia)
• France Génomique (France)
• Takara Holdings Inc. (Japan)
• Genexa AG (Switzerland)