- In February 2025, Medtronic earned U.S. FDA approval for the world's first Adaptive Deep Brain Stimulation (aDBS) system for people with Parkinson's disease. This closed-loop system, which builds on the existing Percept neurostimulator with BrainSense technology, self-adjusts DBS therapy to individual brain activity in real time, marking a significant advancement in personalized neuromodulation
- In January 2025, Medtronic achieved CE Mark approval for its BrainSense Adaptive Deep Brain Stimulation (aDBS) system and Electrode Identifier. This European approval allows for the rollout of the world's only closed-loop DBS system with real-time, self-adjusting brain stimulation for Parkinson's patients, offering enhanced precision in programming and therapy optimization
- In February 2025, Boston Scientific announced that it received both U.S. Food and Drug Administration (FDA) approval and CE mark for its Vercise Cartesia X and HX Directional Leads. These are designed for more precise targeting for enhanced clinical outcomes when used with the Vercise Genus Deep Brain Stimulation System, representing an advancement in lead technology for DBS
- In January 2024, Abbott received FDA approval for its Liberta RC DBS system. This is noted as the smallest rechargeable deep brain stimulation device designed for treating movement disorders, offering features such as the NeuroSphere Virtual Clinic for remote programming, thereby enhancing patient convenience and broadening adoption
- In March 2025, Abbott's pivotal multi-site, randomized TRANSCEND trial investigating the use of its DBS system for treatment-resistant depression (TRD) kicked off with the first implantation procedure at Mount Sinai in New York City. This trial aims to gather further evidence on the impact of DBS for TRD, following its Breakthrough Device Designation from the FDA in 2022.
- In August 2023, Enspire DBS Therapy announced the completion of a USD 17.6 million Series B financing round. The funds are intended to advance the development of DBS combined with rehabilitation for stroke patients, aiming to improve motor recovery outcomes through this integrated approach
