Global Deep Partial-Thickness Thermal Burns Treatment Market Size, Share, and Trends Analysis Report – Industry Overview and Forecast to 2032

Deep Partial-Thickness Thermal Burns Treatment Market Size

• The global deep partial-thickness thermal burns treatment market size was valued at USD 1.34 billion in 2024 and is expected to reach USD 2.49 billion by 2032, at a CAGR of 8.10% during the forecast period
• The market growth is primarily driven by the increasing incidence of burn injuries, especially in low and middle-income countries, coupled with advancements in wound care and regenerative medicine technologies
• Moreover, the growing adoption of novel biologics, skin substitutes, and advanced dressing solutions is enhancing patient outcomes, driving demand across healthcare settings. These developments are fueling market expansion as clinicians and facilities increasingly adopt innovative treatment modalities for effective burn management

Deep Partial-Thickness Thermal Burns Treatment Market Analysis

• Treatments for deep partial-thickness thermal burns, which affect the deeper dermal layers of the skin, are becoming increasingly essential in trauma care due to their complexity, risk of infection, and need for advanced wound healing solutions in both civilian and military healthcare settings
• The growing demand for effective treatment options is primarily driven by rising burn injury cases globally, increased awareness of burn care, and advancements in skin regeneration technologies such as bioengineered skin substitutes, cellular therapies, and antimicrobial dressings
• North America dominated the deep partial-thickness thermal burns treatment market with the largest revenue share of 40.2% in 2024, characterized by strong healthcare infrastructure, significant R&D investments, and government initiatives promoting access to advanced burn care, with the U.S. leading in adoption of novel wound care products and early-stage clinical interventions
• Asia-Pacific is expected to be the fastest growing region in the deep partial-thickness thermal burns treatment market during the forecast period due to increasing industrial accidents, expanding healthcare access, and growing government initiatives for trauma and emergency care
• Fire Burn Injuries segment dominated the deep partial-thickness thermal burns treatment market with a market share of 45.5% in 2024, driven by its high incidence rate and the severity of tissue damage requiring intensive and prolonged treatment

Report Scope and Deep Partial-Thickness Thermal Burns Treatment Market Segmentation 

Deep Partial-Thickness Thermal Burns Treatment Market Trends

“Advancements in Regenerative Therapies and Biologics for Enhanced Healing”

• A significant and accelerating trend in the global deep partial-thickness thermal burns treatment market is the increasing adoption of advanced regenerative therapies and biologics such as bioengineered skin substitutes, growth factor-infused dressings, and stem cell therapies. These innovations are enhancing the speed and quality of burn wound healing while minimizing scarring and complications
  • For instance, products such as Integra Dermal Regeneration Template and Biobrane are increasingly used in major burn centers due to their effectiveness in promoting dermal regeneration and reducing the need for autografting. Similarly, Epicel, a cultured epidermal autograft, is applied in severe cases to aid re-epithelialization
• These biologics often contain components that mimic the natural skin matrix, allowing for better cellular integration and wound coverage. Emerging therapies also incorporate antimicrobial peptides or growth factors to reduce infection risk and accelerate tissue repair, improving overall patient outcomes
• The integration of regenerative medicine with advanced wound care protocols facilitates a more comprehensive and patient-specific approach to burn management. Multidisciplinary treatment plans combining biologics with surgical intervention, rehabilitation, and nutrition support contribute to faster recovery and reduced hospitalization times
• This trend towards biologically advanced, personalized treatment options is transforming the clinical approach to burn care. Consequently, companies such as Vericel and Organogenesis are investing heavily in next-generation biologic solutions tailored for deep partial-thickness burns
• The demand for effective, regenerative treatments is rapidly increasing across trauma centers, military medicine, and specialized burn units as healthcare providers prioritize healing outcomes, functional recovery, and long-term quality of life

Deep Partial-Thickness Thermal Burns Treatment Market Dynamics

Driver

“Rising Burn Injury Incidence and Advancements in Wound Care Technologies”

• The increasing incidence of burn injuries worldwide, particularly deep partial-thickness thermal burns caused by fire, scalds, and industrial accidents, is a significant driver fueling the demand for advanced treatment solutions
  • For instance, in January 2024, Vericel Corporation expanded access to its FDA-approved Epicel cultured epidermal autograft, targeting severe burn cases across more U.S. trauma centers. Such developments from key players are expected to drive the burn treatment market growth during the forecast period
• As global healthcare systems face rising patient volumes from burn-related trauma, the need for effective, timely interventions has become more urgent. Advanced wound care product such as skin substitutes, antimicrobial dressings, and cellular therapies offer better outcomes and faster recovery, making them essential in modern burn management protocols
• Furthermore, improvements in emergency medical services and greater awareness of burn treatment guidelines are driving early-stage intervention, which enhances the success of biologic and regenerative treatments in deep burns
• The demand for evidence-based, outcome-focused therapies in both civilian and military healthcare systems, along with growing investments in regenerative medicine and surgical innovations, continues to strengthen the market. Expanding access to advanced burn care in emerging regions and integration of telemedicine for post-burn rehabilitation also contribute to sustained market growth.

Restraint/Challenge

“Skin Irritation Issues and Regulatory Compliance Hurdle”

• The use of advanced wound care products and biologics in the treatment of deep partial-thickness thermal burns presents a significant challenge due to the potential for skin irritation, allergic reactions, and compatibility issues in sensitive or compromised patients. These concerns can deter broader adoption of certain products in clinical settings
  • For instance, specific bioengineered skin substitutes and antimicrobial dressings have been reported to cause localized inflammation or delayed healing in some patients, prompting caution among healthcare providers when treating high-risk individuals
• Addressing these biocompatibility concerns through the development of gentler formulations, hypoallergenic materials, and rigorous patient screening protocols is crucial for enhancing treatment outcomes and clinician confidence. Companies such as Vericel and Mölnlycke emphasize the safety profile and clinical validation of their products to address these challenges in the market. In addition, the complex regulatory landscape for advanced therapies, particularly biologics, poses significant hurdles to market entry, with lengthy approval processes and high compliance costs acting as barriers for smaller players and slowing innovation
• While regulatory frameworks are gradually evolving to support novel therapies, the burden of extensive clinical documentation, post-market surveillance, and varied regional standards can still hinder the timely availability of promising treatments.
• Overcoming these challenges through clearer regulatory guidance, improved clinician education, and the expansion of reimbursement pathways will be critical to accelerating the adoption of safe, effective, and accessible burn treatment options

Deep Partial-Thickness Thermal Burns Treatment Market Scope

The market is segmented on the basis of burn type, treatment, route of administration, end-user, and distribution channel.

• By Burn Type

On the basis of burn type, the market is segmented into fire burn injuries, scald burn, and hot objects. The fire burn injuries segment dominated the market with the largest market revenue share of 45.5% in 2024, driven by the high incidence of fire-related accidents and the severity of resulting burns that frequently require advanced treatment. Fire burns often lead to deep tissue damage necessitating the use of biologics, grafts, and prolonged clinical care, making this segment a major driver of market demand.

The scald burn segment is anticipated to witness notable growth from 2025 to 2032, fueled by its prevalence in domestic settings, especially among children and elderly populations. Increased awareness about pediatric burn care and improved first-response systems are contributing to faster intervention and treatment, expanding the scope of this segment

• By Treatment

On the basis of treatment, the market is segmented into initial wound care, physical and occupational therapy, and others. The initial wound care segment dominated the market with the highest revenue share in 2024, owing to its critical role in the first phase of burn treatment. This includes cleansing, debridement, and application of advanced wound dressings or biologics, which are essential for preventing infections and facilitating early healing. The segment continues to grow due to technological advancements in wound care materials and biologic integration.

The physical and occupational therapy segment is expected to register the fastest growth rate during the forecast period, driven by the increasing importance of functional recovery and scar management post-injury. Rehabilitation therapies have become a standard part of comprehensive burn care, especially in specialized burn centers and trauma hospitals.

• By Route Of Administration

On the basis of the route of administration, the market is segmented into topical, oral, and others. The topical segment held the largest market revenue share in 2024, attributed to its dominant use in managing burn wounds through antimicrobial creams, dressings, and biologics applied directly to the affected area. Topical treatments offer immediate wound coverage and local action, reducing systemic side effects and promoting faster healing.

The oral segment is projected to witness steady growth during forecast period, driven by the use of oral pain relievers, anti-inflammatories, and antibiotics as supportive therapy during the treatment and recovery process. Although not primary, these are essential in comprehensive burn care.

• By End User

On the basis of end-user, the market is segmented into hospitals & specialty clinics, ambulatory surgical centers, home healthcare, and others. The hospitals & specialty clinics segment dominated the market with the largest share in 2024, due to the availability of specialized burn units, advanced treatment infrastructure, and skilled healthcare professionals. Complex cases of deep partial-thickness burns require hospitalization, driving the demand for treatment in these settings.

The home healthcare segment is expected to witness the fastest growth from 2025 to 2032, supported by the rising trend of post-discharge wound care at home, coupled with advancements in portable wound treatment solutions and increasing preference for at-home recovery.

• By Distribution Channel

On the basis of distribution channel, the market is segmented into direct tender, hospital pharmacy, online pharmacy, retail pharmacy, and others. The direct tender and hospital pharmacy segments together held the largest revenue share in 2024, as hospitals and government organizations procure burn treatment products through centralized, bulk purchasing contracts. These channels ensure consistent supply and regulated pricing, especially for biologics and dressings.

The online pharmacy segment is anticipated to grow at the fastest CAGR during the forecast period, driven by increasing digitalization of healthcare, ease of access to prescription burn products, and rising adoption of e-commerce platforms for medical supplies.

Deep Partial-Thickness Thermal Burns Treatment Market Regional Analysis

• North America dominated the deep partial-thickness thermal burns treatment market with the largest revenue share of 40.2% in 2024, driven by strong healthcare infrastructure, significant R&D investments, and government initiatives promoting access to advanced burn care
• Patients and healthcare providers in the region prioritize rapid healing, reduced scarring, and infection control, driving demand for advanced dressings, biologics, and enzymatic debridement agents
• This dominance is further supported by favorable reimbursement policies, government burn prevention programs, and a robust pipeline of clinical research, positioning the region as a key hub for innovative burn care solutions

U.S. Deep Partial-Thickness Thermal Burns Treatment Market Insight

The U.S. deep partial-thickness thermal burns treatment market secured the largest revenue share of 78% in 2024 within North America, driven by advanced healthcare facilities and early adoption of innovative wound care solutions. The increasing incidence of burn injuries and strong presence of specialized burn centers are propelling the demand for enzymatic debridement agents, skin substitutes, and bioengineered dressings. Moreover, favorable reimbursement frameworks and robust R&D initiatives support market expansion across both military and civilian populations.

Europe Deep Partial-Thickness Thermal Burns Treatment Market Insight

The Europe market is projected to grow at a significant CAGR over the forecast period, fueled by rising awareness of burn management, supportive government policies, and advancements in wound care technologies. Increased burn cases from occupational and domestic accidents, coupled with a growing elderly population, are enhancing demand for effective treatment options. The presence of several global and local players focused on tissue regeneration and scar prevention is accelerating regional growth.

U.K. Deep Partial-Thickness Thermal Burns Treatment Market Insight

The U.K. market is expected to register a notable CAGR, driven by heightened public healthcare investments and emphasis on rapid wound healing and reduced hospitalization. Growing awareness campaigns and the presence of advanced burn treatment protocols in the National Health Service (NHS) are encouraging early intervention. Demand for antimicrobial dressings and minimally invasive debridement methods is also on the rise.

Germany Deep Partial-Thickness Thermal Burns Treatment Market Insight

The Germany’s market is set to grow steadily, supported by a mature healthcare infrastructure and strong research focus on regenerative medicine. The country’s emphasis on quality care and cost-effective treatment is fostering the use of biosynthetic and cellular therapies. With high awareness of skin integrity and post-burn aesthetics, patients and providers are leaning toward advanced therapies over traditional methods.

Asia-Pacific Deep Partial-Thickness Thermal Burns Treatment Market Insight

The Asia-Pacific market is projected to expand at the fastest CAGR from 2025 to 2032, driven by growing burn incidence, healthcare reforms, and technological advancements across China, India, and Southeast Asia. Rising investments in burn care units and increased training for healthcare workers are improving treatment access. In addition, the affordability of novel therapies and the surge in medical tourism are broadening patient reach.

Japan Deep Partial-Thickness Thermal Burns Treatment Market Insight

The Japan’s market is advancing due to its aging population and high healthcare standards. The demand for precise and less painful treatment methods is fostering innovation in enzymatic debridement and autologous cell therapies. Hospitals are integrating digital monitoring for wound progression, enhancing treatment outcomes and patient compliance.

India Deep Partial-Thickness Thermal Burns Treatment Market Insight

The India dominated the Asia-Pacific market revenue share in 2024, driven by a high incidence of domestic and industrial burn injuries and increasing public-private partnerships in healthcare. The country's expanding access to wound care products and rising awareness through national health campaigns are fueling adoption. Furthermore, cost-effective local production and strong NGO involvement are improving burn treatment delivery across urban and rural areas

Deep Partial-Thickness Thermal Burns Treatment Market Share

The deep partial-thickness thermal burns treatment industry is primarily led by well-established companies, including:

• Smith+Nephew (U.K.)
• MediWound (Israel)
• 3M (U.S.)
• Organogenesis Inc. (U.S.)
• DeRoyal Industries, Inc. (U.S.)
• AVITA Medical (U.S.)
• Mölnlycke Health Care AB (Sweden)
• Flen Health (U.S.)
• Medline Industries, Inc (Switzerland)
• Anika Therapeutics, Inc (U.S.)
• MiMedx (U.S.)
• B. Braun SE (Germany)
• Integra LifeSciences (U.S.)
• AdvaCare Pharma (U.S.)
• QRSKIN (South Korea)
• Tissue Reginix (Netherlands)
• Johnson & Johnson Services, Inc. (U.S.)
• Pfizer Inc, (U.S.)
• Mallinckrodt (Dublin)

What are the Recent Developments in Global Deep Partial-Thickness Thermal Burns Treatment Market?

• In April 2025, Interim results from a prospective observational study, indicated that Ovine Forestomach Matrix (OFM) facilitated rapid burn healing with minimal pain, good cosmetic outcomes, and high patient satisfaction in treating deep partial-thickness burns. The study, involving 15 patients, highlighted OFM's potential as a cost-effective and patient-friendly single-application approach to burn management, reducing the need for additional interventions
• In April 2025, Hydrogel Dressings Revolutionizing Burn Care, A review article published in 2025 highlighted the increasing popularity and significant benefits of hydrogel dressings in burn care, especially for chronic burn wounds. These dressings contribute to wound moisture, provide cooling and soothing effects, and aid in autolytic debridement. The review emphasizes their role in wound healing and tissue regeneration, indicating continued innovation in this area of advanced wound care
• In December 2024, Kerecis, a company known for its pioneering use of sustainably sourced fish skin in medical applications, announced the expansion of its silicone fish-skin combination product range for surgical and trauma wounds with SurgiClose® Silicone. While not exclusively for deep partial-thickness burns, this type of advanced biologic product is often applicable in complex wound care scenarios, including burn reconstruction, demonstrating the continued evolution of tissue regeneration solutions in the broader wound care market
• In March 2023, Convatec Inc. obtained FDA clearance for its innovative medical device, InnovaBurn, designed for the management of complex surgical wounds and partial-thickness burns. This placental extracellular matrix technology offers advanced solutions for second-degree burns, addressing critical needs in the deep partial-thickness thermal burns treatment market by enhancing wound management capabilities
• In December 2022, MediWound Ltd. received FDA clearance for NexoBrid, a breakthrough product for treating severe thermal burns in adults. This innovative non-surgical debridement option addresses a crucial need in the market by providing effective and efficient management of severe burn injuries

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