- In February 2025, Guts UK and Bowel Research UK published the final report from their Diverticular Disease Priority Setting Partnership (PSP), identifying the top 10 research priorities—including flare‑up management, prevention strategies, microbiome role, and long‑term diet. This report sets the agenda for future clinical studies aimed at improving patient outcomes
- In April 2025, Spanish biotech Mikrobiomik began recruiting for its DIREBIOT Phase II clinical trial at Ramón y Cajal University Hospital (Madrid), testing a microbiota‑based, antibiotic‑free therapy (MBK‑01) for recurrent uncomplicated diverticulitis—a novel treatment path targeting microbiome modulation
- In May 2025, a study published in Annals of Internal Medicine found that inclusion of nuts and seeds in the diet does not increase diverticulitis risk, debunking longstanding dietary restrictions and potentially easing nutritional guidance for patients



