- Ligases are a class of enzymes that catalyze the joining of two molecules by forming a new chemical bond, typically with the hydrolysis of a diphosphate bond in ATP or a similar energy donor. In biotechnology and molecular biology, ligases are crucial for DNA replication and repair, where DNA ligases help seal nicks in the DNA backbone. These enzymes are fundamental in gene cloning, genetic engineering, and next-generation sequencing (NGS) workflows
- The global ligases enzyme market is experiencing steady growth due to increased applications in genomics, personalized medicine, forensic analysis, and diagnostics. With the surge in biopharmaceutical R&D, CRISPR gene editing, and synthetic biology, the demand for high-purity, high-efficiency ligases is rising
- North America is expected to dominate the global ligases enzyme market with a market share of approximately 42.8% in 2025, driven by advanced research infrastructure, a high demand for biotechnology solutions, and a strong presence of leading enzyme producers in the region
- Asia-Pacific is expected to be the fastest growing region in the global ligases enzyme market, with a projected market share of approximately 26.7% in 2025, driven by rapid advancements in biotechnology research, increased adoption of genetic engineering techniques, and growing investments in life sciences and molecular biology
- Bacterial segment segment is expected to dominate the market with a market share of 34.6% due to its widespread application in molecular biology procedures such as DNA cloning, ligation, and gene expression studies
