“Growing Adoption of Mixed-Mode Resins for High Selectivity and Cost-Efficient Purification”
- A significant trend in the global mixed mode chromatography resin market is the rising demand for resins that combine multiple interaction mechanisms—such as ion exchange and hydrophobic interactions within a single chromatography step. This enables higher selectivity and simplifies purification processes, particularly in biopharmaceutical manufacturing
- Mixed Mode Chromatography Resins are increasingly favored in the purification of complex biologics like monoclonal antibodies (mAbs), vaccines, and plasma-derived products due to their ability to handle impurities that conventional resins struggle to remove
- For example, leading manufacturers are developing resins that offer enhanced binding capacity, salt tolerance, and operational flexibility, allowing for better process economics and more robust downstream workflows
- The growing pressure on pharmaceutical and biotechnology companies to improve production efficiency, reduce purification costs, and meet stringent regulatory standards is accelerating the integration of mixed mode chromatography resins in commercial bioprocessing operations
- This trend towards high-performance, multi-functional chromatography solutions is reshaping downstream processing, offering industries a viable path to address complex purification challenges with fewer process steps and lower resource consumption
