“Growing Popularity of Nasal Route for Systemic Drug Delivery”
- The nasal route is increasingly being adopted for systemic therapies such as pain relief, hormone delivery, and neurological treatments, beyond its traditional use in allergy or cold remedies
- Its efficiency lies in the nasal cavity's vascular structure, which enables rapid drug absorption and avoids first-pass metabolism, improving the overall effectiveness of medications
- For instance, intranasal naloxone is widely used for emergency opioid overdose reversal, offering fast action when seconds matter
- For instance, esketamine nasal spray has been approved for patients with treatment-resistant depression, offering a non-invasive and rapid-acting alternative to traditional antidepressants
- Pharmaceutical companies are exploring nasal delivery for vaccines and biologics, and for instance, intranasal COVID-19 vaccines developed in India and China show how the route is expanding into preventive healthcare
