- In April 2020, Polaryx Therapeutics has received approval from the U.S. Food and Drug Administration (FDA) to initiate a clinical trial investigating PLX-200 as a potential treatment for juvenile Batten disease. Originally developed as a cholesterol-lowering drug, PLX-200 works by binding to its receptor, retinoid X receptor-alpha (RXRa), which triggers a series of molecular processes believed to enhance lysosome formation and function
