Global Nucleic Acid Based Drugs Market – Industry Trends and Forecast to 2029

Global Nucleic Acid Based Drugs Market, By Category (Antisense, siRNA, miRNA, Aptamer, Decoy, CpG-oilgo), Structure (Single Stranded DNA/RNA, Double Stranded DNA, Single-Stranded DNA, Others), Target (Transcriptor Factor, TLR9-Receptor, Protein), Mechanism (Inhibits the Physiological Effect, Adjuvant, Inhibits Transcription, Others), End-Users (Hospitals, Specialty Clinics, Homecare, Others), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Online Pharmacy, Others) – Industry Trends and Forecast to 2029

Market Analysis and Size

Novel treatment techniques based on nucleic acid medicines are being developed. Due to unique properties that allow them to address undruggable targets using traditional small molecule or protein/antibody-based biologics, they promise in treating human diseases such as malignancies, viral infections, and genetic abnormalities. Nucleic acid medications use nucleotide sequence information to influence the biological processes of cells. These medications act either because of their expression in cells or because of the control of genes, particularly those with complementary sequences.

Data Bridge Market Research analyses that the nucleic acid based drugs market was valued at USD 26.75 million in 2021 and is expected to reach USD 113.50 million by 2029, registering a CAGR of 19.80% during the forecast period of 2022 to 2029. The market report curated by the Data Bridge Market Research team includes in-depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.

Report Scope and Market Segmentation

Market Definition

Target therapeutics based on nucleic acids or closely related chemical substances are known as nucleic acid-based drugs. These medications have the ability to target disorders at the genetic level and prevent disease-causing proteins from being expressed. The major active elements in nucleic acids are oligonucleotides, made via chemical synthesis, and tiny molecules. Nucleic acids are usually thought of as drug transporters, and they can cause undesired biological responses such immune system activation and blood clotting pathway extension. As a result, the advantages of nucleic acid-based pharmaceuticals in possible drug delivery systems for controlled drug releases are the primary rationale for their increased use in the market.

Nucleic Acid Based Drugs Market Dynamics

Drivers

• Rise in the prevalence of multi-genetic disorders

The surging prevalence of multi-genetic disorders such as diabetes, neurodegenerative diseases, cancer and cardiovascular diseases is a major factor driving the nucleic acid based drugs market's growth rate. Small molecules or protein/antibody-based biologics are currently the most clinically authorized medications, including those treating cancer. Nucleic acid medications are next-generation drugs that have taken a lot of time and effort to create. It's been 40 years since nucleic acid was discovered to prevent virus reproduction.

• Increasing investment for healthcare infrastructure

Another significant factor influencing the growth rate of nucleic acid based drugs market is the rising healthcare expenditure which helps in improving its infrastructure. Also, various government organizations aims to improve the healthcare infrastructure by increasing funding and this will further influence the market dynamics.

Furthermore, rising initiatives by public and private organizations to spread awareness will expand the nucleic acid based drugs market. Additionally, high disposable income and changing lifestyle of people will result in the expansion of nucleic acid based drugs market. Along with this, rising prevalence of thalassemia, haemophilia, sickle cell anaemia, and cystic fibrosis will enhance the market's growth rate.

Opportunities

• Increase in the number of research and development activities       

Moreover, the market's growth is fueled by an increase in the number of research and development activities. This will provide beneficial opportunities for the nucleic acid based drugs market growth. Along with this, rising drug approvals and launches will further propel the market's growth rate.

Moreover, rising investment for the development of advanced technologies and an increase in the number of emerging markets will further provide beneficial opportunities for the growth of nucleic acid-based drugs during the forecast period.

Restraints/Challenges

On the other hand, the expiration of patented drugs and the introduction of generic version of drugs will obstruct the market's growth rate. The lack of healthcare infrastructure in developing economies and high cost associated with drugs will challenge the nucleic acid based drugs market. Additionally, side effects linked with nucleic acid-based drugs will restrain and further impede the growth rate of the market during the forecast period of 2022-2029.

This nucleic acid based drugs market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the nucleic acid based drugs market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

Patient Epidemiology Analysis

Nucleic acid based drugs market also provides you with detailed market analysis for patient analysis, prognosis and cures. Prevalence, incidence, mortality, adherence rates are some of the data variables that are available in the report. Direct or indirect impact analyses of epidemiology to market growth are analysed to create a more robust and cohort multivariate statistical model for forecasting the market in the growth period.

COVID-19 Impact on Nucleic Acid Based Drugs Market

The COVID-19 outbreak and subsequent lockdown in numerous countries around the world had an impact on the financial status of enterprises in all sectors. The private healthcare sector is one of the areas where the pandemic had a significant impact. The pandemic's lockdown has put a financial strain on the private healthcare industry in a number of countries. Outpatient visits, manpower, equipment, consumables, and other resources were reduced. Furthermore, the coronavirus pandemic had a significant influence on medicine development, production, supply, and the businesses of different healthcare corporations around the world. The outbreak has resulted in the shutdown of industrial establishments, with the exception of those that manufacture critical commodities, and disruptions in product supply chains. As a result, the COVID-19 outbreak had impacted the economy in three ways: directly influencing production and demand, causing distribution channel disruptions, and having a financial impact on firms and financial markets. However, now that COVID-19 vaccines are readily available, numerous authorities are trying to assure that life-saving medications and vaccines are supplied without interruption. Hence, the market is projected to stabilize in the future.

Global Nucleic Acid Based Drugs Market Scope

The nucleic acid based drugs market is segmented on the basis of category, structure, target, mechanism, end-users and distribution channel. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Category

• Antisense
• SiRNA
• MiRNA
• Aptamer
• Decoy
• CpG-oilgo

Structure

• Single Stranded DNA/RNA
• Double Stranded DNA
• Single-Stranded DNA
• Others

Target

• Transcriptor Factor
• TLR9-Receptor
• Protein

Mechanism

• Inhibits the Physiological Effect
• Adjuvant
• Inhibits Transcription
• Others

End-Users

• Hospitals
• Specialty Clinics
• Homecare
• Others

Distribution Channel

• Hospital Pharmacy
• Retail Pharmacy
• Online Pharmacy
• Others

Nucleic Acid Based Drugs Market Regional Analysis/Insights

The nucleic acid based drugs market is analyzed and market size insights and trends are provided by country, category, structure, target, mechanism, end-users and distribution channel as referenced above.

The countries covered in the nucleic acid based drugs market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America

North America dominates the nucleic acid based drugs market in terms of market share and market revenue and will continue to flourish its dominance during the forecast period. This is due to the presence of major key players and rising healthcare expenditure will further propel the market's growth rate in this region. Additionally, increasing research and development activities will further propel the market's growth rate in this region.

Asia-Pacific are expected to grow during the forecast period of 2022-2029 due to surging number of research and development activities in this region. Also, the development of healthcare infrastructure will further propel themarket's growth rate in this region.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.   

Competitive Landscape and Nucleic Acid Based Drugs Market Share Analysis

The nucleic acid based drugs market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to nucleic acid based drugs market.

Some of the major players operating in the nucleic acid based drugs market are:

• Eli Lilly and Company (US)
• Wave Life Sciences Ltd. (US)
• Copernicus Therapeutics Inc. (US)
• Imugene (Australia)
• PYC Therapeutics (Australia)
• Protagonist Therapeutics Inc. (US)
• Benitec Biopharma (Australia)
• Egen, Inc. (US)
• Biomedica Medizinprodukte GmbH (UK)
• Transgene (France)
• Arrowhead Pharmaceuticals, Inc. (US)
• Ionis Pharmaceuticals (US)
• Alnylam Pharmaceuticals, Inc. (US)
• Moderna, Inc. (US)
• Gotham Therapeutics (US)
• Sumitomo Chemical Co., Ltd. (Japan)