- In April 2025, researchers introduced Acoustic Loudness Factor (ALF)—a new benchmark parameter designed for small-molecule photoacoustic probes. ALF enables accurate prediction of dye performance in vivo, accelerating probe design and improving signal quality in diagnostic imaging
- In February March 2025, scientists at Wayne State University used PAI combined with pattern recognition to reveal distinct neural activation patterns in the prefrontal cortex during conditioned learning in rats—highlighting PAI’s emerging role in neuroscience research
- In April 2025, Duke University researchers published findings on using Acoustic Loudness Factor for benchmarking and enhancing small-molecule photoacoustic probes, setting a new standard for design and preclinical evaluation
- In May 2025, a joint A*STAR–NHG group in Singapore unveiled a first-in-human trial combining MSOT and AI-based segmentation for 3D tumor imaging—including basal cell carcinoma diagnostics—demonstrating high-resolution efficacy and potential to guide surgical planning
- In March 2025, Nature Reviews Bioengineering featured a commentary titled “Defining the clinical niche for photoacoustic imaging,” highlighting its growing therapeutic relevance in oncology and cardiovascular diagnostics—underscoring accelerated clinical adoption
