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Global Sitosterolemia Market – Industry Trends and Forecast to 2030

Pharmaceutical

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Global Sitosterolemia Market – Industry Trends and Forecast to 2030

  • Pharmaceutical
  • Upcoming Report
  • Oct 2023
  • Global
  • 350 Pages
  • No of Tables: 220
  • No of Figures: 60

Global Sitosterolemia Market – Industry Trends and Forecast to 2030

Market Size in USD Billion

CAGR :  % Diagram

Diagram Forecast Period 2022–2030
Diagram Market Size (Base Year) USD 915.60 USD Million
Diagram Market Size (Forecast Year) USD 1,437.44 USD Million
Diagram CAGR %

Major Markets Players

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Global Sitosterolemia Market, By Type (Phytosterols, sterols from animals), Treatment (Dietary restrictions, bile acid sequestrants, ezetimibe), Symptoms (xanthomas, macrothrombocytopenia, thrombocytopenia, stomatocytes joint stiffness and pain), Diagnosis (Blood test, Genetic testing), End-Users (Clinics, Hospitals, Diagnostic centres, Surgical centres, others), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Online Pharmacy) – Industry Trends and Forecast to 2030.

Sitosterolemia Market

Sitosterolemia Market Analysis and Size

Rise in the prevalence of liver diseases, genetic history of sitosterolemia, advancement in treatment technologies, rising awareness towards genetic diseases and lipid related disorders with genetic counselling expand the growth of the global sitosterolemia market. Rise in number of R&D activities and clinical trials along with its therapeutic treatments are expected to provide beneficial opportunities for the global sitosterolemia market in the forecast period 2023-2030.           

Data Bridge Market Research analyses that the global sitosterolemia market which was USD 915.6 million in 2022, is expected to reach USD 1437.44 million by 2030, and is expected to undergo a CAGR of 5.80% during the forecast period 2023-2030. This indicates that the market value. “Blood test” dominates the diagnosis segment of the global sitosterolemia market owing to an increase in the demand of blood test for diagnosis of sitosterolemia. In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.

Sitosterolemia Market Scope and Segmentation

Report Metric

Details

Forecast Period

2023 to 2030

Base Year

2022

Historic Years

2021 (Customizable to 2015-2020)

Quantitative Units

Revenue in USD Million, Volumes in Units, Pricing in USD

Segments Covered

Type (Phytosterols, sterols from animals), Treatment (Dietary restrictions, bile acid sequestrants,  ezetimibe), Symptoms (xanthomas, macrothrombocytopenia, thrombocytopenia, stomatocytes  joint stiffness and pain), Diagnosis (Blood test, Genetic testing), End-Users (Clinics, Hospitals, Diagnostic centres, Surgical centres, others), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Online Pharmacy)

Countries Covered

U.S., Canada, Mexico, Brazil, Argentina, Peru, Rest of South America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Hungary, Lithuania, Austria, Ireland, Norway, Poland, Rest of Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Vietnam, Rest of Asia-Pacific, Saudi Arabia, U.A.E, Egypt, Israel, Kuwait, South Africa, Rest of Middle East and Africa

Market Players Covered

Amryt Pharma plc (Ireland), AstraZeneca plc (U.K.), Eli Lilly and Company (U.S.), Genzyme Corporation (a subsidiary of Sanofi) (U.S.), Johnson & Johnson (U.S.), Merck & Co., Inc. (U.S.), Pfizer Inc. (U.S.), Regeneron Pharmaceuticals, Inc. (U.S.), Sanofi S.A. (France), Novartis AG (Switzerland), Recordati Rare Diseases Inc. (U.S.), Alexion Pharmaceuticals, Inc. (U.S.), Vertex Pharmaceuticals Incorporated (U.S.), Retrophin, Inc. (U.S.), Alnylam Pharmaceuticals, Inc. (U.S.), Ionis Pharmaceuticals, Inc. (U.S.), Amgen Inc. (U.S.), Mylan N.V. (now Viatris Inc.) (U.S.), Takeda Pharmaceutical Company Limited (Japan), Horizon Therapeutics plc (Ireland)

Market Opportunities

  • Launch of innovative and technologically advanced products to meet the needs of customers
  • Increase in the prevalence of infectious diseases
  • Increase in the number of mergers and acquisitions among manufacturers

Market Definition

Sitosterolemia, also known as phytosterolemia, is a rare genetic disorder characterized by the excessive absorption of dietary plant sterols and cholesterol in the intestine due to mutations in the ABCG5 or ABCG8 genes. This leads to elevated levels of plant sterols in the bloodstream, along with increased levels of LDL cholesterol, increasing the risk of early-onset atherosclerosis, heart disease, and stroke. Individuals with sitosterolemia may also develop xanthomas, fatty deposits under the skin.            

Global Sitosterolemia Market Dynamics

Drivers

  • Increasing Prevalence of Genetic and Rare Diseases

Sitosterolemia offer targeted and personalized treatment options for genetic and rare diseases. As the understanding of these diseases improves and more targets are identified, the demand for sitosterolemia is expected to rise.

  • Increased Awareness and Diagnosis

Growing awareness of rare genetic disorders, including sitosterolemia, among healthcare professionals and patients is likely to drive increased diagnosis rates. Advances in genetic testing and screening technologies may also contribute to earlier and more accurate detection of the condition.

  • Rising Research and Development 

Pharmaceutical and biotechnology companies are increasingly investing in research and development efforts to better understand the underlying causes of sitosterolemia and to develop novel treatments. These investments can lead to the discovery of new therapeutic approaches, drugs, and therapies for managing the condition.

  • Growing Investment for Healthcare Facilities

Surging focus towards improving the condition of healthcare facilities and improving the overall healthcare infrastructure another important factor fostering the growth of the market. Rising number of partnerships and strategic collaborations between the public and private players pertaining to funding and application of new and improved technology is further creating lucrative market opportunities.  

Opportunities

  • Personalized medicine and precision therapies

Advances in genomics and personalized medicine offer opportunities to tailor treatments specifically to individuals with sitosterolemia based on their genetic profiles. Precision therapies, including gene therapies or gene editing technologies, may become increasingly viable for treating this rare genetic disorder.

  • Patient Advocacy and Support Services

The global sitosterolemia market can benefit from the development of patient advocacy groups and support services. These organizations can raise awareness, provide resources, and offer support to individuals and families affected by the condition. Companies that align themselves with these initiatives can improve patient acc ess to treatments and enhance their reputation in the market.

Restraints/ Challenges

  • Limited Patient Population

The small patient population affected by sitosterolemia can be a market restraint. Pharmaceutical companies may be hesitant to invest in research and development for rare diseases due to the limited number of potential patients. This can lead to a lack of available treatment options and therapies for those with the condition.

  • High Development Costs

Developing treatments for rare diseases can be costly and time-consuming. Clinical trials may require a small number of participants but still demand significant resources. Companies may be hesitant to invest in such endeavors, especially if the potential return on investment is uncertain.

  • Limited Disease Understanding

Sitosterolemia is a rare genetic disorder, and there is still much to learn about its underlying mechanisms and long-term effects. This lack of comprehensive understanding can hinder the development of effective treatments and therapies.

  • Regulatory Hurdles

Obtaining regulatory approval for new treatments for rare diseases can be complex. Companies must navigate the regulatory pathways specific to orphan drugs, which may involve demonstrating safety and efficacy with limited clinical trial data due to the small patient population.

This global sitosterolemia market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the global sitosterolemia market Contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

Recent Development

  • In June 2022, Kensing LLC, a manufacturer of plant sterols, natural vitamin E, and high-purity surfactants, announced the acquisition of Vitae Naturals, a manufacturer of plant sterol esters and non-GMO vitamin E derivatives which have their applications in skincare, food, and nutrition end-use industry
  • In February 2022, Elicit Plant, an AGtech company specializing in crops’ water resistance and developing innovative phytosterol-based solutions, raised a USD 17.26 million series. The funds will be used to advance international growth and R&D programs for its phytosterol-based solution that addresses water stress and allows farmers to respond to climate change challenges.

Global Sitosterolemia Market Scope

The global sitosterolemia market is segmented on the basis of type, treatment, symptoms, diagnosis, end-users and distribution channel. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Type

  • Phytosterols
  • Sterols from Animals

Treatment

  • Dietary Restrictions
  • Bile Acid Sequestrants
  • Ezetimibe

Symptoms

  • Xanthomas
  • Macrothrombocytopenia
  • Thrombocytopenia
  • Stomatocytes
  • Joint stiffness
  • Pain

Diagnosis

End-Users

  • Clinics
  • Hospitals
  • Diagnostic Centers
  • Surgical Centers
  • Others

Distribution Channel

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacy

 Global Sitosterolemia Market Regional Analysis/Insights

The global sitosterolemia market is analysed and market size insights and trends are provided by country, type, treatment, symptoms, diagnosis, end-users and distribution channel as referenced above.

The countries covered in the global sitosterolemia market report are U.S., Canada, Mexico, Brazil, Argentina, Peru, Rest of South America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Hungary, Lithuania, Austria, Ireland, Norway, Poland, Rest of Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Vietnam, Rest of Asia-Pacific, Saudi Arabia, U.A.E, Egypt, Israel, Kuwait, South Africa, Rest of Middle East and Africa.

North America dominates the global sitosterolemia market because of the existence of major players, rise in the significance of treatment, well-developed healthcare sector and increase in the government support for research & development in this region. global sitosterolemia market in Europe and the Asia Pacific is expected to grow during the forecast period due to the advancement in treatment technologies, rise in the research and development activities, increasing government support and growing healthcare expenditure.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points like down-stream and upstream value chain analysis, technical trends and porter's five forces analysis, case studies are some of the pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.   

Healthcare Infrastructure Growth Installed Base and New Technology Penetration

The global sitosterolemia market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipment, installed base of different kind of products for global sitosterolemia market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the global sitosterolemia market. The data is available for historic period 2015-2020. 

Competitive Landscape and Global Sitosterolemia Market Share Analysis

The global sitosterolemia market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to global sitosterolemia market.

Some of the major players operating in the global sitosterolemia market are:

  • Amryt Pharma plc (Ireland)
  • AstraZeneca plc (U.K.)
  • Eli Lilly and Company (U.S.)
  • Genzyme Corporation (U.S.)
  • Johnson & Johnson (U.S.)
  • Merck & Co., Inc. (U.S.)
  • Pfizer Inc. (U.S.)
  • Regeneron Pharmaceuticals, Inc. (U.S.)
  • Sanofi S.A. (France)
  • Novartis AG (Switzerland)
  • Recordati Rare Diseases Inc. (U.S.)
  • Alexion Pharmaceuticals, Inc. (U.S.)
  • Vertex Pharmaceuticals Incorporated (U.S.)
  • Retrophin, Inc. (U.S.)
  • Alnylam Pharmaceuticals, Inc. (U.S.)
  • Ionis Pharmaceuticals, Inc. (U.S.)
  • Amgen Inc. (U.S.)
  • Mylan N.V. (now Viatris Inc.) (U.S.)
  • Takeda Pharmaceutical Company Limited (Japan)
  • Horizon Therapeutics plc (Ireland)


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FREQUENTLY ASK QUESTIONS

The sitosterolemia market size will be worth USD 1437.44 million by 2030.
The growth rate of the sitosterolemia market is 5.80% in the forecast period by 2030.
The increasing prevalence of genetic and rare diseases & increased awareness and diagnosis are the growth drivers of the sitosterolemia market.
Type, treatment, symptoms, diagnosis, end-users and distribution channel are the factors on which the sitosterolemia market research is based.
Major companies in the sitosterolemia market are Amryt Pharma plc (Ireland), AstraZeneca plc (U.K.), Eli Lilly and Company (U.S.), Genzyme Corporation (a subsidiary of Sanofi) (U.S.), Johnson & Johnson (U.S.), Merck & Co., Inc. (U.S.), Pfizer Inc. (U.S.), Regeneron Pharmaceuticals, Inc. (U.S.), Sanofi S.A. (France), Novartis AG (Switzerland), Recordati Rare Diseases Inc. (U.S.), Alexion Pharmaceuticals, Inc. (U.S.), Vertex Pharmaceuticals Incorporated (U.S.), Retrophin, Inc. (U.S.), Alnylam Pharmaceuticals, Inc. (U.S.), Ionis Pharmaceuticals, Inc. (U.S.), Amgen Inc. (U.S.), Mylan N.V. (now Viatris Inc.) (U.S.), Takeda Pharmaceutical Company Limited (Japan), Horizon Therapeutics plc (Ireland).
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