- Topical keratolytics, which aid in the removal of excess keratin from the skin’s surface, are increasingly recognized as essential dermatological treatments for conditions such as acne, psoriasis, warts, calluses, and ichthyosis. These solutions are gaining popularity in both prescription and OTC formats due to their effectiveness and ease of application
- The escalating demand for topical keratolytics is primarily fueled by the growing prevalence of chronic skin conditions, increasing focus on skincare, and a rising preference for non-invasive, at-home treatment options
- North America dominated the topical keratolytics market with the largest revenue share of 39.6% in 2024, driven by high awareness of dermatological health, strong purchasing power, and wide availability of both branded and generic formulations. The U.S. leads the region with robust consumer spending on dermatology products, including salicylic acid, urea, and lactic acid-based treatments
- Asia-Pacific is expected to be the fastest-growing region in the topical keratolytics market, with a projected CAGR of 7.9% from 2025 to 2032, driven by rising disposable incomes, increasing skincare awareness, and expanding access to dermatological products through e-commerce and retail pharmacies in countries such as India, China, and South Korea
- The salicylic acid segment dominated the topical keratolytics market with a market share of 42.1% in 2024, attributed to its broad application across acne, dandruff, warts, and psoriasis. Its exfoliating and comedolytic properties, along with widespread OTC availability, make it a first-line ingredient in keratolytic treatment formulations



