- In June 2023, Plexus Worldwide introduced Plexus Sleep, a sugar-free gummy supplement designed to enhance restorative sleep and regulate a healthy sleep cycle. The formula includes 5 mg of melatonin, 1.7 grams of prebiotic fiber FOS (fructooligosaccharides), ashwagandha, GABA, lemon balm extract, and L-tryptophan
- In May 2023, Octarine Bio, a synthetic biology company, partnered with Ginkgo Bioworks to explore compounds in the tryptophan pathway. Their collaboration aims to engineer a strain for producing violacein, a natural bis-indole pigment known for its anti-microbial, anti-oxidant, and UV protective properties
- In September 2022, Zesty Paws expanded its product line with three new cat supplements, Hemp Elements Plus Calming Bites, Hemp Elements Plus Hairball Bites, and Aller-Immune Bites. Developed in collaboration with CBDistillery™, the calming bites feature broad-spectrum hemp extract, delivering 3 mg of CBD per two chews, alongside L-Theanine, L-Tryptophan, chamomile, ashwagandha, melatonin, and valerian root for stress relief
- In August 2022, Youtheory, a supplement brand renowned for its collagen products, launched a new range of liquid dietary supplements. Previously, collagen was criticized as a low-quality protein due to its lack of tryptophan, earning a score of 0 on the PDCAAS (Protein Digestibility-Corrected Amino Acid Score)



