Global Protein Purification and Isolation Market at a Significant Rate in The Forecast Period 2018-2025

Global Protein Purification and Isolation Market According to Data Bridge Market Research new Market report, “By Technology (Ultrafiltration, Precipitation, Preparative Chromatography Techniques {Affinity Chromatography [Immobilized Metal Ion Affinity Chromatography, Immunoaffinity Chromatography, Bead Based Chromatography], Ion Exchange Chromatography, Reverse Phase Chromatography, Hydrophobic Interaction Chromatography, Size Exclusion Chromatography}, Electrophoresis {Gel Electrophoresis, Isoelectric Focusing, Capillary Electrophoresis}, Western Blotting, Dialysis, Diafiltration,  Centrifugation), By Product Type (Instruments {Purification Systems, Software}, Consumables {Kits, Reagents, Columns, Resins, Beads, Others}), By Application (Drug Screening, Target Identification, Biomarker Discovery, Protein-Protein Interaction Studies, Protein Therapeutics, Disease Diagnosis, Monitoring), By End-User (Biotech, Pharma Industries, Contract Research Organization, Academic Research Institutes, Hospital, Diagnosis Centers), By Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa) - Industry Trends and Forecast is projected to reach USD  10717.57 million by 2025, at a CAGR of 8.5% during the forecast period of 2018 to 2025.

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Global Protein Purification and Isolation Market

Proteins purification and isolation techniques are used to study the structures and functions of proteins which are further used for industrial and pharmaceutical application. To obtain highly purified proteins is an important step before initiating any practical and operational research. Automated instrument are used for sample loading, elute sample, wash the column and collects peak steps for ion-exchange, metal affinity, hydrophobic interaction and gel filtration chromatography. For the development of drugs and in the diagnosis & monitoring of diseases purified and isolated proteins are in high demand.

According to an article published by National Center for Biotechnology Information in 2011, in silico identification of new ligands for protein GPR17 is a promising therapeutic target for human neurodegenerative diseases.

Abbkine, Inc., is a provider of innovative, high quality assay kits, recombinant proteins, antibodies and other research tools launched PurKine GST-Tag protein purification kit which is also known as glutathione or GST resin. These resin kit is used to purify high levels of overexpressed GST-tagged fusion proteins in gravity column procedure at different scales.

Segmentation: Global Protein Purification and Isolation Market

The global market for protein purification by the following sub-categories is presented

  • By Technology

    • Ultrafiltration
    • Precipitation
    • Preparative Chromatography Techniques

      • Affinity Chromatography

        • Immobilized Metal Ion Affinity Chromatography
        • Immunoaffinity Chromatography
        • Bead Based Chromatography

      • Ion Exchange Chromatography
      • Reverse Phase Chromatography
      • Hydrophobic Interaction Chromatography
      • Size Exclusion Chromatography

    • Electrophoresis

      • Gel Electrophoresis
      • Isoelectric Focusing
      • Capillary Electrophoresis

    • Western Blotting
    • Dialysis
    • Diafiltration
    • Centrifugation

  • By Product Type

    • Instruments

      • Purification Systems
      • Software

    • Consumables

      • Kits
      • Reagents
      • Columns
      • Resins
      • Beads
      • Others

  • By Application

    • Drug Screening
    • Target Identification
    • Biomarker Discovery
    • Protein-Protein Interaction Studies
    • Protein Therapeutics
    • Disease Diagnosis
    • Monitoring

  • By End-User

    • Biotech
    • Pharma Industries
    • Contract Research Organization
    • Academic Research Institutes
    • Hospital
    • Diagnosis Centers

  • By Geography

    • North America
    • South America
    • Europe
    • Asia-Pacific
    • Middle East and Africa


Technological development towards rapid purification kits:

Protein purification kits contain reagents, buffer, gels, ladders, immunoglobulins which helps to carry out isolation and purification of proteins.

Sigma-Aldrich, which is a subsidiary of Merck KGaA offers genElute RNA/DNA/protein plus purification kit. It provides a rapid method for the isolation and purification of total RNA, genomic DNA and proteins sequentially from a single sample of cultured animal cells, small tissue samples, blood, bacteria, yeast, fungi or plants.

Norgen Biotek Corp., is a biotechnology company and provider of advanced powerful tools for nucleic acid and protein purification launched its All-in-One Purification Kit for 4-in-1 purification of RNA, microRNA, DNA and proteins from a single sample.

The growing numbers of protein analysis, recombinant proteins have increased the demand of purification kits for rapid and accurate purification and isolation of proteins which is fueling the growth of the market.

Increasing importance of identification of new ligands:

Ligands are the ion or molecules that bind to a central atom to form a co-ordination complex. Protein–ligand interactions are fundamental processes occurring in living organisms. Ligands are used in the purification of protein as they bind to the epitopes of the proteins. In chromatography, ligands are attached to targeted protein isolation and purification.

According to an article published in National Center for Biotechnology Information, in 2012, the specific ligand was identified for the methionine biosynthesis transcriptional regulator by frontal affinity chromatography coupled to mass spectrometry. It is used for the identification and characterization of the small molecules that modulate transcriptional regulator binding to transcriptional regulator targets.

Repligen, which is a bioprocessing-focused life sciences company offers protein A affinity ligand, which has been used in over 450 commercial processes and in 300 clinical trials. Identification of new ligands has been increased owing to the better and precise isolation and purification of targeted proteins methods. There is an increase in the production of recombinant proteins to purify such proteins and new ligands are also expected to drive the market.

Some of the major market players in protein purification and isolation market are Thermo Fisher Scientific Inc,  Sigma-Aldrich Co, QIAGEN, General Electric Company, Bio-Rad Laboratories, Inc, Agilent Technologies, Promega Corporation, Purolite, BioVision, Inc, Insolution Ltd, Norgen Biotek Corp, PerkinElmer Inc, Abcam plc, Bertin Bioreagent, Advansta Inc. among others.

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