Global Bone Cement and Glue Market Size, Share, and Trends Analysis Report – Industry Overview and Forecast to 2032

Bone Cement and Glue Market Size

• The global bone cement and glue market size was valued at USD 473.77 billion in 2024 and is expected to reach USD 724.33 billion by 2032, at a CAGR of 5.45% during the forecast period
• The bone cement and glue market growth is significantly driven by the increasing number of elderly individuals globally, who are more susceptible to age-related bone disorders such as osteoporosis and osteoarthritis, often requiring surgical intervention with bone cement and glue
• The increasing number of road accidents causing trauma and the rising incidence of sports injuries leading to fractures and other orthopedic conditions are significant drivers for the bone cement and glue market, as these materials are crucial in repair and stabilization procedures

Bone Cement and Glue Market Analysis

• Bone cement and glue are medical adhesives used in orthopedic surgeries to anchor implants or stabilize bone fractures. Bone cement, typically made from polymethyl methacrylate (PMMA), is a widely used material in joint replacement surgeries such as hip, knee, and shoulder arthroplasty. It helps to secure prosthetic components to the bone, providing stability and promoting better fixation. Bone glue, on the other hand, is a more recent development, designed to offer stronger bonding properties and better biocompatibility. It is often used in minimally invasive procedures, fracture fixation, and spinal surgeries
• The expanding adoption of bone cement and glue is primarily attributable to the increasing prevalence of orthopedic disorders, spinal conditions, and trauma cases, particularly among the aging population. The rising popularity of minimally invasive surgeries, where bone cement plays a crucial role in stabilizing bones, is also contributing to market growth. Advancements in material science have led to improved performance, biocompatibility, and reduced complications
• North America dominates the bone cement and glue market with a share of 35.5% in 2024 due to a growing number of orthopedic surgeries and an increasing demand for advanced bone fixation materials
• Asia-Pacific is expected to be the fastest growing region in the bone cement and glue market with a share of during the forecast period due to an increasing number of orthopedic surgeries due to a growing geriatric population, rising disposable incomes, and improving healthcare infrastructure across the region
• Bone cement segment dominates the market with a market share of 60.5% in 2024 due to its widespread use in orthopedic surgeries, particularly for joint fixation and vertebral augmentation. Its high compressive strength, quick setting time, and long-established clinical safety record make bone cement the standard choice for stabilizing implants, especially in aging populations with osteoporosis

Report Scope and Bone Cement and Glue Market Segmentation     

Bone Cement and Glue Market Trends

“Increasing Demand for Orthopedic Procedures”

• A significant and accelerating trend in the bone cement and glue market is the increasing demand for orthopedic procedures across the globe. This growing demand is fueled by a rising geriatric population susceptible to age-related bone disorders such as osteoporosis and arthritis, as well as an increase in sports-related injuries and trauma cases requiring surgical intervention and bone fixation
  • For instance, major companies at the forefront of orthopedic treatments, such as Stryker Corporation and Zimmer Biomet Holdings, Inc., experience a direct impact from the higher volume of joint replacements, spinal fusions, and fracture repairs, where bone cement and glue are essential. Leading manufacturers of bone cement and glue, including Heraeus Medical LLC and DePuy Synthes (Johnson & Johnson), cater to this growing demand by providing a wide range of bone fixation products for various orthopedic procedures
• This heightened demand for orthopedic procedures necessitates the increased use of bone cement and glue to provide immediate stability, enhance implant fixation, and improve long-term outcomes for patients undergoing surgery. Compared to historical treatment methods, modern orthopedic procedures often rely on bone cement and glue for their reliability and ability to facilitate quicker patient recovery and improved mobility
• The growing emphasis on improving the quality of life for an aging population, coupled with advancements in orthopedic surgical techniques and implant technologies, is further fueling the importance of bone cement and glue as critical components in a wide range of orthopedic interventions. The increasing awareness of treatment options and the willingness of patients to undergo surgery to address mobility issues also contribute to this trend
• Healthcare organizations and patients are increasingly acknowledging the benefits of orthopedic procedures utilizing bone cement and glue for their effectiveness in pain relief, functional restoration, and overall improvement in patient well-being. This trend towards proactive orthopedic care and surgical solutions is driving substantial growth and investments in the bone cement and glue market
• The demand for reliable and effective bone fixation materials is growing rapidly as the increasing number of orthopedic procedures performed encourages healthcare providers to utilize bone cement and glue to ensure successful surgical outcomes and improved patient satisfaction, ultimately boosting the growth and significance of the bone cement and glue market within the broader healthcare landscape

Bone Cement and Glue Market Dynamics

Driver

“Increasing Prevalence of Orthopedic Conditions”

• A significant and growing driver for the bone cement and glue market is the increasing prevalence of various orthopedic conditions across the globe. This rise in conditions such as osteoarthritis, rheumatoid arthritis, and osteoporosis, along with a growing number of bone fractures due to falls and accidents, necessitates the use of bone cement and glue in a wide range of surgical interventions to alleviate pain, restore function, and improve patient mobility
  • For instance, major players in the pharmaceutical and medical device industries, such as Pfizer (which markets bone health medications) and Novartis (involved in osteoporosis treatments), indirectly contribute to the demand for orthopedic surgeries that utilize bone cement and glue provided by companies such as Exactech, Inc. and Cardinal Health, Inc. These bone cement and glue manufacturers cater to the increased number of patients requiring surgical fixation and joint replacement procedures as a result of these prevalent orthopedic conditions
• As the global population ages and lifestyle factors contribute to a higher incidence of musculoskeletal disorders, the demand for effective treatments, including those utilizing bone cement and glue, continues to rise. Bone cement and glue play a crucial role in providing the necessary support and stability during surgeries aimed at addressing these prevalent orthopedic issues, leading to improved patient outcomes and a greater demand for these materials
• Healthcare organizations and research institutions are increasingly acknowledging the direct correlation between the growing prevalence of orthopedic conditions and the increased need for reliable bone fixation solutions such as cement and glue. This trend is driving substantial research and development efforts within the bone cement and glue market to create more effective and biocompatible materials to address the expanding patient pool suffering from these conditions
• The demand for dependable and clinically proven bone fixation materials is growing rapidly as the increasing prevalence of orthopedic conditions encourages healthcare providers to rely on bone cement and glue as integral tools in their treatment strategies, ultimately boosting the growth and overall importance of the bone cement and glue market within the broader healthcare sector dedicated to musculoskeletal health

Restraint/Challenge

“High Cost of Advanced Materials”

• A notable challenge for the bone cement and glue market arises from the high cost associated with advanced materials used in their formulation. The development and manufacturing of innovative bone cements and glues with enhanced properties, such as bioactive or injectable options, often require specialized and expensive materials. This can significantly impact the overall cost of these products, potentially limiting their widespread adoption, especially in regions with constrained healthcare budgets
  • For instance, while companies such as Stryker Corporation and Zimmer Biomet Holdings, Inc. offer advanced bone cement formulations, the cost of raw materials for these products, including specialized polymers and bioactive agents, can be substantially higher than traditional bone cement. Leading manufacturers such as Heraeus Medical LLC and DePuy Synthes (Johnson & Johnson) also face this challenge in balancing innovation with affordability, particularly when developing next-generation bone adhesives and cements
• Addressing this challenge requires ongoing research and development in material science to discover and utilize more cost-effective yet equally effective advanced materials. The high cost of these materials can restrict the accessibility of cutting-edge bone fixation solutions, potentially leading healthcare providers in certain regions to opt for more conventional, albeit potentially less advanced, bone cement and glue products
• Despite the clinical benefits offered by advanced bone cement and glue formulations, the high cost of their constituent materials can be a concern for healthcare systems and patients, influencing treatment choices and market growth. This economic factor can sometimes hinder the broader implementation of innovative solutions, particularly in emerging economies where affordability is a significant consideration
• Overcoming these limitations involves collaborative efforts between material scientists, manufacturers, and regulatory bodies to promote the development and approval of advanced bone cement and glue options that are clinically superior and also economically viable. Continuous innovation aimed at reducing the cost of advanced materials or finding suitable, less expensive alternatives is crucial for the sustained growth and accessibility of the bone cement and glue market

Bone Cement and Glue Market Scope

The market is segmented on the basis of type, application, and end-user.

• By Type

On the basis of type, the market is segmented into bone cement and bone glue. The bone cement is further sub segmented into polymethyl methacrylate (PMMA) cement, calcium phosphate cement (CPC), glass polyalkenoate cement (GPC), antibiotic-loaded bone cement, and non-antibiotic-loaded bone cement. The bone glue is further sub segmented into natural bone glue and synthetic bone glue. The bone cement segment dominates with the largest market revenue share of 60.5% in 2024, driven by its widespread use in orthopedic surgeries, particularly for joint fixation and vertebral augmentation. Its high compressive strength, quick setting time, and long-established clinical safety record make bone cement the standard choice for stabilizing implants, especially in aging populations with osteoporosis.

The bone glue segment is expected to witness the fastest CAGR from 2025 to 2032, driven by growing demand for minimally invasive procedures and biologically compatible materials. Bone glue offers advantages such as reduced surgical time, improved tissue integration, and elimination of the need for mechanical fixation, making it increasingly attractive in pediatric and trauma applications. Advances in synthetic bioadhesives and regenerative medicine further support its rapid market expansion.

• By Application

On the basis of application, the market is segmented into arthroplasty, total knee arthroplasty, total hip arthroplasty, total shoulder arthroplasty, kyphoplasty, and vertebroplasty. The arthroplasty segment dominates the largest market revenue share in 2024, driven by the rising prevalence of osteoarthritis and the aging population. Arthroplasty procedures, particularly hip and knee replacements, rely heavily on bone cements for implant fixation, and the global increase in joint replacement surgeries supports the dominance of this application segment.

The vertebroplasty segment is expected to witness the fastest CAGR from 2025 to 2032, driven by increasing cases of spinal compression fractures and the growing preference for minimally invasive spinal procedures. Vertebroplasty involves the injection of bone cement to stabilize vertebral fractures, offering rapid pain relief and recovery. The technique's expanding adoption, especially among geriatric patients, contributes to its accelerated market growth.

• By End-User

On the basis of end-user, the market is segmented into hospitals, ambulatory surgical centers, and clinics. The hospitals segment dominates the largest market revenue share in 2024, driven by high patient volume, availability of advanced surgical infrastructure, and the performance of complex orthopedic and trauma procedures. Hospitals remain the primary setting for joint replacements and spinal surgeries, which require bone cements and glues, sustaining strong demand in this segment.

The ambulatory surgical centers segment is expected to witness the fastest CAGR from 2025 to 2032, driven by the shift toward outpatient orthopedic surgeries and the benefits of cost-efficiency and shorter recovery times. These centers increasingly adopt bone fixation materials for procedures such as minimally invasive joint and spine treatments, aided by advancements in surgical techniques and patient preference for same-day discharge.

Bone Cement and Glue Market Regional Analysis

• North America dominates the bone cement and glue market with the largest revenue share of 35.5% in 2024, driven by a growing number of orthopedic surgeries and an increasing demand for advanced bone fixation materials
• The rising prevalence of age-related bone disorders and sports injuries, along with a high awareness of advanced medical treatments, fuels the market in this region. Consumers in North America prioritize effective and reliable bone repair solutions, leading to a strong demand for bone cement and glue in both hospitals and specialized clinics
• This widespread adoption is supported by developed healthcare infrastructure, favorable reimbursement policies, and a large aging population, establishing bone cement and glue as essential materials in orthopedic procedures

U.S. Bone Cement and Glue Market Insight

U.S. bone cement and glue market captures a significant revenue share within North America, fueled by a high volume of orthopedic surgeries, including joint replacements and trauma cases. Consumers are increasingly seeking advanced surgical interventions for bone injuries and chronic conditions, driving the demand for high-quality bone cement and glue. The growing preference for minimally invasive procedures and the availability of technologically advanced bone fixation products further propel this market. Moreover, the presence of major orthopedic device manufacturers and continuous advancements in material science significantly contribute to the market's expansion.

Europe Bone Cement Market Insight

European bone cement market is projected to expand at a moderate CAGR throughout the forecast period, primarily driven by an increasing elderly population and rising investments in orthopedic healthcare. The growing awareness of available treatment options for bone-related ailments and a focus on improving the quality of life for the aging population are fostering the adoption of bone cement in various surgical procedures. European consumers are also drawn to the long-term stability and support offered by bone cement in joint replacements and fracture repairs. The region is experiencing consistent growth across hospitals and orthopedic centers, with bone cement being a standard component in a wide range of surgeries.

U.K. Bone Cement Market Insight

U.K. bone cement market is anticipated to maintain a steady growth rate during the forecast period, driven by a consistent demand for orthopedic surgeries and a focus on efficient healthcare delivery. In addition, concerns regarding bone health and mobility among the aging population are encouraging both patients and healthcare providers to opt for solutions involving bone cement. The UK's well-established healthcare system and the presence of skilled orthopedic surgeons support the continued use of bone cement in various applications.

Germany Bone Cement Market Insight

German bone cement market is expected to expand at a stable CAGR during the forecast period, fueled by a strong emphasis on high-quality healthcare and technological advancements in medical treatments. Germany's well-developed healthcare infrastructure and a high number of orthopedic surgeries contribute to the significant use of bone cement, particularly in joint replacement procedures. The market is characterized by the presence of leading manufacturers and a focus on innovative and reliable bone fixation solutions, aligning with the country's reputation for engineering excellence.

Asia-Pacific Bone Cement Market Insight

Asia-Pacific bone cement market is poised to grow at a significant CAGR in the coming years, driven by an increasing number of orthopedic surgeries due to a growing geriatric population, rising disposable incomes, and improving healthcare infrastructure across the region. The region's growing medical tourism and the increasing adoption of Western medical practices are also contributing to the demand for bone cement. Furthermore, as local manufacturing capabilities expand and healthcare access improves, the affordability and accessibility of bone cement are increasing, benefiting a wider patient base.

Japan Bone Cement Market Insight

Japan bone cement market is experiencing steady growth, driven by a rapidly aging population and a high prevalence of osteoporosis, leading to a greater need for joint replacement and fracture repair surgeries. The Japanese market prioritizes high-quality medical treatments and places a significant emphasis on the long-term success of orthopedic procedures, making bone cement a preferred material for ensuring stability and support. The increasing number of elderly individuals seeking to maintain an active lifestyle is further fueling the demand for effective bone repair solutions.

China Bone Cement Market Insight

China bone cement market is anticipated to grow at a robust CAGR, attributed to the country's large and rapidly aging population, increasing incidence of orthopedic disorders, and improving healthcare infrastructure. As more people gain access to advanced medical treatments and the demand for a better quality of life increases, the adoption of bone cement in orthopedic surgeries is rising significantly. The government's support for healthcare advancements and the growing number of skilled orthopedic surgeons are key factors propelling the market in China.

Bone Cement and Glue Market Share

The bone cement and glue industry is primarily led by well-established companies, including:

• 3M (U.S.)
• Essity Health & Medical (Germany)
• Stryker (U.S.)
• Zimmer Biomet (U.S.)
• Heraeus Group (Germany)
• Smith & Nephew (U.K.)
• Enovis Corporation (U.S.)
• Medtronic (Ireland)
• Globus Medical (U.S.)
• Johnson & Johnson Services Inc. (U.S.)
• Arthrex Inc. (U.S.)
• aap Implantate AG (Germany)
• Exactech, Inc. (U.S.)
• Teknimed (France)
• Artivion, Inc (U.S.)
• Cardinal Health (U.S.)
• Demetra Holding S.p.A. (Italy)
• Orthofix Medical Inc. (U.S.)

Latest Developments in Global Bone Cement and Glue Market

• In February 2024, Exactech, a leader in joint replacement surgery innovations, partnered with Statera Medical to develop the world’s first smart reverse shoulder implant. This groundbreaking collaboration aims to combine Exactech's expertise in implants and instruments with Statera Medical's advanced technology. The new implant is expected to revolutionize shoulder replacement procedures with its smart, connected features
• In March 2024, Stryker, a global leader in medical technology, announced the completion of its acquisition of SERF SAS, a French joint replacement company, from Menix. This acquisition strengthens Stryker’s portfolio in the joint replacement market. It is expected to enhance Stryker's offerings and expand its presence in the global orthopedic sector
• In September 2023, HippoFi, Inc. announced a strategic partnership with Zimmer Biomet to revolutionize the spinal biologics sector. The collaboration aims to launch an innovative synthetic biomaterial designed to promote bone growth, set for release in 2024 under HippoFi's biologic subsidiary, PUR Biologics. In addition, HippoFi/PUR secured FDA 510(K) clearance for their ActiveOrbTM technology and obtained an exclusive global license from Zimmer Biomet for the spinal market
• In 2021, Smith & Nephew (U.K.) acquired Integra Life Sciences' Extremity Orthopedics business to enhance its product offerings in shoulder, upper, and lower extremities. This strategic acquisition aimed to broaden Smith & Nephew's portfolio in orthopedic solutions. It reflects the company's commitment to strengthening its position in the global extremities market
• In 2021, Zimmer Biomet (U.S.) completed the spinoff of its spine and dental businesses into a new publicly traded company, ZimVie Inc. ("ZimVie"). This strategic move was designed to sharpen the focus of both Zimmer Biomet and ZimVie on meeting the specific needs of patients and customers. The transaction aimed to maximize value for stockholders by allowing both companies to concentrate on their core areas of expertise

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