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Global Lysosomal Acid Lipase Deficiency Treatment Market – Industry Trends and Forecast to 2030

Pharmaceutical

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Global Lysosomal Acid Lipase Deficiency Treatment Market – Industry Trends and Forecast to 2030

  • Pharmaceutical
  • Upcoming Report
  • Dec 2022
  • Global
  • 350 Pages
  • No of Tables: 220
  • No of Figures: 60

Global Lysosomal Acid Lipase Deficiency Treatment Market – Industry Trends and Forecast to 2030

Market Size in USD Billion

CAGR :  % Diagram

Diagram Forecast Period 2022–2030
Diagram Market Size (Base Year) USD 649.02 USD Million
Diagram Market Size (Forecast Year) USD 1,528.34 USD Million
Diagram CAGR %

Major Markets Players

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Global Lysosomal Acid Lipase Deficiency Treatment Market, By Treatment (Enzyme Replacement Therapy, Lipid Modifying Agents (Statins), Surgery, Supportive Care), Therapy Type (Liver Transplant, Hematopoietic Stem Cell Transplant), Indication (Wolman Disease, Cholesteryl Ester Storage Disease), End-Users (Hospitals, Specialty Clinics, Others), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, online Pharmacies and Others) – Industry Trends and Forecast to 2030.

Lysosomal Acid Lipase Deficiency Treatment Market

Lysosomal Acid Lipase Deficiency Treatment Market Analysis and Size

According to the National Institute for Health and Care Excellence (NICE) 2019, around 70% of individuals suffering from lysosomal acid lipase deficiencies risk developing liver problems and eventually requiring a liver transplant. Lysosomal acid lipase deficiency is a very rare disease and occurs in only about 1 out of 500,000 individuals, typically in newborn babies. Cholesterol Ester Storage Disease (CESD) is more predominant and often affects children and adolescents.

Data Bridge Market Research analyses a growth rate in the lysosomal acid lipase deficiency treatment market in the forecast period 2023-2030. The expected CAGR Lysosomal acid lipase deficiency treatment market is tend to be around 11.3% in the mentioned forecast period. The market was valued at USD 649.02 million in 2022, and it would grow upto USD 1528.34 million by 2030. In addition to the market insights such as market value, growth rate, market segments, geographical coverage, market players, and market scenario, the market report curated by the Data Bridge Market Research team also includes in-depth expert analysis, patient epidemiology, pipeline analysis, pricing analysis, and regulatory framework.

Lysosomal Acid Lipase Deficiency Treatment Market Scope and Segmentation

Report Metric

Details

Forecast Period

2023 to 2030

Base Year

2022

Historic Years

2021 (Customizable to 2015 - 2020)

Quantitative Units

Revenue in USD Million, Volumes in Units, Pricing in USD

Segments Covered

Treatment (Enzyme Replacement Therapy, Lipid Modifying Agents (Statins), Surgery, Supportive Care), Therapy Type (Liver Transplant, Hematopoietic Stem Cell Transplant), Indication (Wolman Disease, Cholesteryl Ester Storage Disease), End-Users (Hospitals, Specialty Clinics, Others), Distribution Channel (Hospital Pharmacy, Retail Pharmacy, online Pharmacies and Others)

Countries Covered

U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America

Market Players Covered

Alexion Pharmaceuticals, Inc (U.S.), Merck & Co., Inc. (U.S.), Pfizer Inc. (U.S.), AstraZeneca (U.K.), Lonza (Switzerland), Thermo Fisher Scientific (U.S.), Teva Pharmaceutical Industries Ltd. (Israel), Lupin (India), Lannett (U.S.), Hetero Healthcare Limited. (India), Zydus Group (India), Sandoz International GmbH (Switzerland), BioCrick BioTech (China)

Market Opportunities

  • Increasing Demand For Liver Transplant

Market Definition

Lysosomal acid lipase deficiency is a rare genetic condition that can lead to extreme liver disease and sometimes gets difficult to diagnose. The disease is mostly caused by mutation in the lysosomal acid lipase (LIPA) gene which results in the accumulation of triglyceride and cholesteryl esters in different tissues of the human body. The primary symptoms include vomiting, diarrhoea, weight loss that eventually leads to malnutrition, hepatomegaly or even death.

Lysosomal Acid Lipase Deficiency Treatment Market Dynamics

Drivers

  • Increasing FDA Approvals of Drugs

The rapid novel innovations, drug development, and research resulted in rapid drug approvals by several organizations such as the FDA and thus it led to the market growth. In 2015, FDA approved genetically modified organisms (GMO) chickens, for the increased production of a recombinant human lysosomal acid lipase (LAL) protein in their eggs that will be used for lysosomal acid lipase (LAL) deficiency treatment. The Europe commission in 2015 granted marketing permission of Kanuma, that can be used for the treatment of LAL deficiency for patients of all age groups, that is expected to boost the growth of kanuma in region.

  • Growing Adoption of Enzyme Replacement Therapy

Among the different treatment types, enzyme replacement therapy is projected to increase the market growth during the forecast period, due to high efficacy and long-term disease control after treatment. Thus, it increases the growth of the market.

Opportunities

  • Increasing Demand For Liver Transplant

As per the National Institute for Health and Care Excellence (NICE) 2016, around 50% of patients who are suffering from lysosomal acid lipase (LAL) deficiency have higher chances of liver complications, that includes cirrhosis or fibrosis and liver transplant. The growing incidences of liver complications due to LAL deficiency is projected to increase demand for liver transplants, boosting the growth of the LAL deficiency treatment market during the forecast period.

Restraints/Challenges

  • Lack of Awareness

For many decades, this deficiency disease is not much known in several parts of the world. The appropriate treatment for the disease and its associated applications are unaware to the people. Thus, it hampers market growth. 

  • High Cost of Treatment Process

The enormous expenditure required for its treatment processes obstructs market growth. Numerous market players make huge investments in manufacturing new and advanced treatment procedures to faster the recovery process and in return the cost is increased.

This  lysosomal acid lipase deficiency treatment market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on the lysosomal acid lipase deficiency treatment market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.

Global Lysosomal Acid Lipase Deficiency Treatment Market Scope

The lysosomal acid lipase deficiency treatment market is segmented on the basis of treatment, therapy type, indication, end-user distribution channel. The growth amongst these segments will help you analyze meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.

Treatment

Therapy Type

  • Liver Transplant
  • Hematopoietic Stem Cell Transplant

Indication

  • Wolman Disease
  • Cholesteryl Ester Storage Disease

End-Users

  • Hospitals
  • Specialty Clinics
  • Others

Distribution Channel

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacies
  • Others

Lysosomal Acid Lipase Deficiency Treatment Market Regional Analysis/Insights

The lysosomal acid lipase deficiency treatment market is analyzed and market size insights and trends are provided by treatment, therapy type, indication, end-user distribution channel as referenced above.

The major countries covered in the lysosomal acid lipase deficiency treatment market report are the U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America is dominating the market due to the presence of key manufacturers of the product is high and, increasing research and development activities.

Asia-Pacific is considered to grow over the coming years due to increased new research and developments on lysosomal acid lipase deficiency treatment market.

The country section of the report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data. 

Competitive Landscape and Global Lysosomal Acid Lipase Deficiency Treatment Market Share Analysis

The lysosomal acid lipase deficiency treatment market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to lysosomal acid lipase deficiency treatment market

Key players operating in the lysosomal acid lipase deficiency treatment market include:

  • Alexion Pharmaceuticals, Inc (U.S)
  • Merck & Co., Inc. (U.S.)
  • Pfizer Inc. (U.S.)
  • AstraZeneca (U.K.)
  • Lonza (Switzerland)
  • Thermo Fisher Scientific (U.S.)
  • Teva Pharmaceutical Industries Ltd. (Israel)
  • Lupin (India)
  • Lannett (U.S.)
  • Hetero Healthcare Limited. (India)
  • Zydus Group (India)
  • Sandoz International GmbH (Switzerland)
  • BioCrick BioTech (China)


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Research Methodology:

Data collection and base year analysis are done using data collection modules with large sample sizes. The stage includes obtaining market information or related data through various sources and strategies. It includes examining and planning all the data acquired from the past in advance. It likewise envelops the examination of information inconsistencies seen across different information sources. The market data is analysed and estimated using market statistical and coherent models. Also, market share analysis and key trend analysis are the major success factors in the market report. To know more, please request an analyst call or drop down your inquiry.

The key research methodology used by DBMR research team is data triangulation which involves data mining, analysis of the impact of data variables on the market and primary (industry expert) validation. Data models include Vendor Positioning Grid, Market Time Line Analysis, Market Overview and Guide, Company Positioning Grid, Patent Analysis, Pricing Analysis, Company Market Share Analysis, Standards of Measurement, Global versus Regional and Vendor Share Analysis. To know more about the research methodology, drop in an inquiry to speak to our industry experts.

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FREQUENTLY ASK QUESTIONS

The lysosomal acid lipase deficiency treatment market was USD 649.02 million in 2022.
The lysosomal acid lipase deficiency treatment market is projected to grow at a CAGR of 11.3% during the forecast period of 2023-2030.
The Lysosomal Acid Lipase Deficiency Treatment Market is segmented into treatment, therapy type, indication, end-user & distribution channel.
North America is dominating the market due to the presence of key manufacturers of the product is high and, increasing research and development activities.
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