Asia-Pacific CRISPR Gene Detection and Diagnostic Market, By Class (Class 1- Multiple Effector Proteins and Class 2 -Single CrRNA-Binding Protein), Products & Services (Products and Services), Application (Biomedical Diagnostics, Genome Engineering, Drug Discovery, Agricultural Applications and Others), Workflow (Sample Preparation, Pre-Amplification, CrRNA, Cas Enzymes and Sensing), End User (Hospitals, Diagnostic Centers, Biotechnology Companies, Academic and Research Institutes and Others), Distribution Channel (Direct Tender, Retail Sales) Industry Trends and Forecast to 2029
Market Definition and Insights
CRISPR is clustered regularly interspaced short palindromic repeats and is a tool for genome editing, it allows researchers to alter DNA sequences and modify gene function easily. It has many potential applications, including correcting genetic defects and treating and preventing the spread of diseases. CRISPR-based diagnostics have been used for many biomedical applications, such as sensing nucleic-acid-based biomarkers of infectious and non-infectious diseases and detecting genetic diseases. The assay kits in CRISPR are composed of two components: a protein called Cas9 and a guide RNA, a string of nucleic acid molecules with a certain genetic code.
This CRISPR-Cas9 system has been modified for use in mammalian cells. We can either knock out specific genes by introducing a guide sequence (sgRNA) specific to our gene of interest by introducing frameshift mutations via Non-Homologous End Joining (NHEJ) or generate knock-in mutations.
CRISPR-Cas 9 systems have extended the scope of diagnostics and services in gene and cell therapies. Pharmaceutical companies invest heavily in R&D to develop new products, with a surge of gene and cell therapy agents entering early development. The market players investing would allow producing safe and effective treatments for patients in serious need.
The Asia-Pacific CRISPR gene detection and diagnostic is supportive and aims to reduce the severity of the symptoms. Data Bridge Market Research analyses that the CRISPR gene detection and diagnostic market will grow at a CAGR of 21.6% during the forecast period of 2022 to 2029.
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Report Metric |
Details |
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Forecast Period |
2022 to 2029 |
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Base Year |
2021 |
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Historic Years |
2020 (Customizable to 2019 - 2014) |
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Quantitative Units |
Revenue in USD Million, Pricing in USD |
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Segments Covered |
By Class (Class 1- Multiple Effector Proteins And Class 2 -Single CrRNA-Binding Protein), Products & Services (Products and Services.), Application (Biomedical Diagnostics, Genome Engineering, Drug Discovery, Agricultural Applications And Others.), Workflow (Sample Preparation, Pre-Amplification, CrRNA, Cas Enzymes And Sensing.), End User (Hospitals, Diagnostic Centers, Biotechnology Companies, Academic And Research Institutes And Others) Distribution Channel (Direct Tender, Retail Sales), |
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Countries Covered |
China, Japan, South Korea, India, Australia, Singapore, Thailand, Malaysia, Indonesia, Philippines And Rest Of Asia-Pacific |
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Market Players Covered |
GenScript, Takara Bio Inc., OriGene Technologies, Inc., Agilent Technologies, Inc., Synthego, Merck KGaA, Integrated DNA Technologies, Inc. (A subsidiary of Danaher) Thermo Fisher Scientific Inc. among others. |
Asia-Pacific CRISPR Gene Detection and Diagnostic Market Dynamics
Drivers
- Rise in prevalence and incidence of chronic diseases
Chronic diseases are common health conditions, where one in three the adults suffer from chronic conditions. Chronic diseases have affected the health and quality of life of many citizens.
CRISPR is abbreviated as clustered regularly interspaced short palindromic repeats. In recent years, CRISPR has become a commanding tool for gene editing, which is used to alter the specific sequences of DNA in a cell. CRISPR has important use in the research and treatment of Huntington’s disease, muscular dystrophy, cancer and high cholesterol.
For instance,
- In 2021, the data by NORD - National Organization for Rare Disorders, Inc. stated the diagnosed incidence of Duchenne Muscular Dystrophy (DMD). The Duchenne Muscular Dystrophy (DMD) is a frequent genetic condition, which affects 1 in 3,500 male births worldwide
- Rise In Investment In Research And Development
Gene editing technologies, such as the CRISPR-Cas 9 system, have extended the scope of diagnostics and services in gene and cell therapies. Pharmaceutical companies invest heavily in R&D to develop new products, with a surge of gene and cell therapy agents entering early development. The market players investing would allow to achieve the goal of producing safe and effective treatments for patients in serious need.
For instance,
- In February 2022, Synthego had raised USD 200 million as an investment for research and development to boost the development of CRISPR-Based Medicines from early-phase research to the clinic. Synthego will use the investment amount from Series E finance to accelerate the creation of CRISPR diagnostics and services
Availability of funding for CRISPR gene diagnostics
CRISPR gene diagnostics and research are funded by the National Institute of Health (NIH) budget. The private sector also funds the CRISPR gene detection and research, but such investment generally occurs later, during the testing and development phase, then during initial basic research. With genome editing being such a new field, an unbiased governmental body must supervise them; the FDA is cautious and thorough, but they are endlessly struggling for funding, making a long-term investment that aligns the payment with the potential future beneficiaries., will further enhance the growth of the CRISPR gene detection and diagnostic market.
Furthermore, advancement in CRISPR gene diagnostics, rising initiatives by public and private organizations to spread awareness and growing government funding are the factors that will expand the Asia-Pacific CRISPR gene detection market. Other factors such as increase in the demand for effective therapies and rising awareness about the timely diagnosis and will positively impact the CRISPR gene detection and diagnostic market's growth rate. Additionally, high disposable income, rising number of chronic diseases, changing lifestyle will result in the expansion of the CRISPR gene detection and diagnostic market.
Opportunities
- The rise in healthcare expenditure
Moreover, the rise in the research and development activities and increasing investments by government and private organization will boost new opportunities for the market's growth rate.
- Strategic initiative by market players
The demand for CRISPR gene detection and diagnosis has increased the demand in the U.S. and Asia-Pacific owing to the timely treatment of chronic conditions. These favorable factors enhance the need for medications, and to achieve the market demand, minor and major market players are utilizing various strategies.
The major players are also trying to devise specific strategies, such as product launches, acquisitions, approvals, expansions, and partnerships, to ensure the smooth running of the business, avoid risks, and increase the long-term growth in the sales of the market.
For instance,
- In May 2021, Horizon Discovery Ltd. extended the gene modulation portfolio with the first synthetic single guide RNA and patent pending dcas9 repressor for CRISPR interference in Waltham. The expansion of the portfolio had increased the sales and revenue of the synthetic guide RNA portfolio across the U.S. and the U.K. region and had increased the collaboration with market players
Also, the launch of effective therapies and continuous clinical trials will provide beneficial opportunities for the CRISPR gene detection and diagnostic market in the forecast period of 2022-2029. Also, high unmet need of current and developments in healthcare technology will escalate the growth rate of the CRISPR gene detection and diagnostic market in future.
Restraints/Challenges
However, high cost of CRISPR diagnostics and risks faced while using the CRISPR diagnostics will impede the growth rate of CRISPR gene detection and diagnostic market. Additionally, the risks incurred while using the MRI devices will hinder the CRISPR gene detection and diagnostic market growth. The lack of skilled expertise and regulations will further challenge the market in the forecast period mentioned above.
- Rise in cost of CRISPR based diagnostics
The vast potential of CRISPR based therapeutics comes with a cost tag. Maximum genome editing therapies require an increased amount of time for development and production, and hence the rise in cost occurs. Besides, the assay kits and medications related to CRISPR gene detection and diagnostic are applicable to large section of population. These costs are pushed on patients. Therefore, the present high cost is expected to show a descending trend in the future.
For instance,
- In July 2021, according to Integrated DNA Technologies, Inc., the first commercially available CRISPR-based diagnostic assay for SARS-CoV-2 including reverse transcription LAMP (RT-LAMP) as preamplification is currently available at USD 30.15 per reaction
The CRISPR gene detection and diagnostic market report provides details of new recent developments, trade regulations, import-export analysis, production analysis, value chain optimization, market share, impact of domestic and localized market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on CRISPR gene detection and diagnostic market contact Data Bridge Market Research for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.
Patient Epidemiology Analysis
According to a study by Globocan. In 2020, breast cancer had high incidence of cases, around 11.7%, followed by lung cancer which is 11.40%, colorectum cancer which is 10.00%, and cervix uteri and oesophagus cancer having less number of incident cases.
CRISPR gene detection and diagnostic market also provides you with detailed market analysis for patient analysis, prognosis and cures. Prevalence, incidence, mortality, adherence rates are some of the data variables that are available in the report. Direct or indirect impact analyses of epidemiology to market growth are analysed to create a more robust and cohort multivariate statistical model for forecasting the market in the growth period.
COVID-19 Impact on the CRISPR Gene Detection and Diagnostic Market
The COVID-19 has negatively affected the market. Lockdowns and isolation during pandemics complicate the diagnosis management and treatment. The lack of access to health-care facilities for routine and medication administration will further affect the market. Social isolation increases stress, despair, and social support, all of which may cause a reduction in anticonvulsant medication adherence during the pandemic.
Recent Development
- In August 2020, SHERLOCK BIOSCIENCES announced a collaboration with Dartmouth-Hitchcock Health, to conduct the clinical trial of SHERLOCK Diagnostic Kit for Sars-CoV-2. The kit received emergency approval from the Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration (FDA).
Asia-Pacific CRISPR Gene Detection and Diagnostic Market Scope
The CRISPR gene detection and diagnostic market is segmented on the basis of six segments: class, products & services, application, workflow, end user, and distribution channel. The growth amongst these segments will help you analyse meagre growth segments in the industries and provide the users with a valuable market overview and market insights to help them make strategic decisions for identifying core market applications.
Class
- Class 1- Multiple Effector Proteins
- Class 2 -Single CrRNA Binding Protein
On the basis of class, the Asia-Pacific CRISPR gene detection and diagnostic market is segmented into class 1- multiple effector proteins and class 2 -single CrRNA binding protein.
Products & Services
- Products
- Services
On the basis of products & services, the Asia-Pacific CRISPR gene detection and diagnostic market is segmented into products & services.
Application
- Biomedical Diagnostics
- Genome Engineering
- Drug Discovery
- Agricultural Applications
- Others
On the basis of application, the Asia-Pacific CRISPR gene detection and diagnostic market is segmented into is segmented into biomedical diagnostics, genome engineering, drug discovery, agricultural applications and others.
Workflow
- Sample Preparation
- Pre-Amplification
- CrRNA
- Cas Enzymes
- Sensing
On the basis of workflow, the Asia-Pacific CRISPR gene detection and diagnostic market is segmented into sample preparation, pre-amplification, CrRNA, Cas enzymes and sensing.
End User
- Hospitals
- Diagnostic Centers
- Biotechnology Companies
- Academic and Research Institutes
- Others
On the basis of end user, the Asia-Pacific CRISPR gene detection and diagnostic market is segmented into hospitals, diagnostic centers, biotechnology companies, academic and research institutes and others.
Distribution Channel
- Direct Tenders
- Retail Sales
On the basis of distribution channel, the Asia-Pacific CRISPR gene detection and diagnostic market is segmented into direct tenders and retail sales.
CRISPR Gene Detection and Diagnostic Market Regional Analysis/Insights
The Asia-Pacific CRISPR gene detection and diagnostic market is analysed and market size insights and trends are provided by regions, class, products & services, application, workflow, end user, and distribution channel as referenced above.
The countries covered in the CRISPR gene detection and diagnostic market report are China, Japan, South Korea, India, Australia, Singapore, Thailand, Malaysia, Indonesia, Philippines And Rest of Asia-Pacific.
The China dominates the CRISPR gene detection and diagnostic market due to the rise in clinical trials for CRISPR based diagnostics.
The country section of the report also provides individual market impacting factors and changes in regulations in the market domestically that impacts the current and future trends of the market. Data points such as new sales, replacement sales, country demographics, disease epidemiology and import-export tariffs are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of Asia-Pacific brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of sales channels are considered while providing forecast analysis of the country data.
Competitive Landscape and CRISPR Gene Detection and Diagnostic Market Share Analysis
The Asia-Pacific CRISPR gene detection and diagnostic market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, the Asia-Pacific presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies' focus related to the CRISPR gene detection and diagnostic market.
Some of the major players operating in the CRISPR gene detection and diagnostic market are GenScript, Takara Bio Inc., OriGene Technologies, Inc., Agilent Technologies, Inc., Synthego, Merck KGaA, Integrated DNA Technologies, Inc. (A subsidiary of Danaher) Thermo Fisher Scientific Inc. among others.
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