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Market Size in USD Billion
| 2025 –2032 | |
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USD 124.68 Million |
| USD 220.71 Million | |
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India Oligonucleotides Synthesis Market Segmentation, By Type (Custom Oligos and Predesigned Oligos), Product Type (Equipment's, Reagents, and Consumables & Accessories), Synthesis Method (Solid Phase Oligo Synthesis Method and Liquid/Enzymatic Phase Oligo Synthesis Method), Application (Diagnostics, Therapeutics, Research, Agriculture, Food and Others), End User (Pharmaceutical and Biotechnology Companies, Diagnostic Centers, Contract Research Organization, Research & Academic Institutes, and Forensic Labs), Distribution Channel (Direct Tender, Retail Sales and Others)- Industry Trends and Forecast to 2032
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India Oligonucleotides Synthesis Key Market Insights
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Segments Covered
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Countries Covered
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Key Market Players
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Market Opportunities
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In addition to the insights on market scenarios such as market value, growth rate, segmentation, geographical coverage, and major players, the market reports curated by the Data Bridge Market Research also include in-depth expert analysis, pricing analysis, brand share analysis, consumer survey, demography analysis, supply chain analysis, value chain analysis, raw material/consumables overview, vendor selection criteria, PESTLE Analysis, Porter Analysis, and regulatory framework.
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Rising Adoption of Advanced Genomics and Personalized Medicine
Driver
Growing Demand Due to Expansion of Biotechnology Research and Precision Medicine
Restraint/Challenge
High Costs and Regulatory Compliance Hurdles
The market is segmented on the basis of type, product type, synthesis method, application, end user, and distribution channel.
On the basis of type, the India oligonucleotides synthesis market is segmented into custom oligos and predesigned oligos. The custom oligos segment dominated the market with the largest revenue share of 65.5% in 2024, driven by its high demand in personalized research, targeted therapeutics, and specialized diagnostic applications requiring tailored DNA and RNA sequences. Pharmaceutical and biotechnology companies rely on custom oligos for gene therapy, molecular diagnostics, and therapeutic development. Academic and research institutes prefer custom sequences for experimental flexibility and high specificity in genomics studies. The segment benefits from fast turnaround times, high-quality synthesis, and expanding applications in precision medicine. Increasing adoption of high-throughput automated synthesis technologies further strengthens the dominance of this segment.
The predesigned oligos segment is expected to witness the fastest growth over the forecast period due to its cost-effectiveness and wide use in routine laboratory research, standard diagnostics, and educational applications. Predesigned oligos simplify workflows, reduce synthesis time, and are suitable for high-volume, repetitive experiments. Academic institutions, teaching labs, and small-scale diagnostic centers increasingly adopt predesigned sequences for rapid deployment. The growth is also fueled by increasing availability from local and international suppliers. This segment provides researchers with ready-to-use oligos, eliminating the need for custom synthesis for common sequences.
On the basis of product type, the India oligonucleotides synthesis market is segmented into equipment, reagents, and consumables & accessories. The reagents & consumables segment dominated the market in 2024, accounting for 55% share, as these are critical for oligonucleotide synthesis workflows. Reagents, including phosphoramidites, buffers, and solvents, are consumed continuously, driving recurring demand. Consumables such as columns, plates, and filters support consistent quality and high yields. Pharmaceutical, biotech, and academic sectors contribute significantly to the segment’s revenue through routine usage. High demand is also driven by expanding research activities and increased adoption of PCR, NGS, and other molecular techniques. Service providers offering reagent kits with standardized quality further enhance market dominance.
The equipment segment is expected to witness the fastest growth during forecast period, driven by the adoption of automated and high-throughput synthesizers that improve efficiency, reproducibility, and reduce human error. Growing R&D activities in genomics, diagnostics, and therapeutics are prompting investments in advanced synthesis platforms. Indian research labs are increasingly replacing manual synthesis workflows with automated instruments. Compact, cost-effective, and high-precision synthesizers designed for Indian laboratories are gaining traction. Equipment innovation, including robotics and integrated software, is accelerating market adoption. Startups and CROs investing in in-house synthesis infrastructure are further boosting segment growth.
On the basis of synthesis method, the India oligonucleotides synthesis market is segmented into solid phase oligo synthesis and liquid/enzymatic phase oligo synthesis. The solid phase oligo synthesis segment dominated in 2024 due to its efficiency, scalability, and suitability for producing long and complex sequences. This method ensures high reproducibility and is compatible with automation, making it the preferred choice for pharmaceutical and biotech applications. It is widely adopted for therapeutic oligos and high-precision custom sequences. Research institutions value solid-phase methods for consistent quality and high yield. The segment is also strengthened by established infrastructure and trained personnel familiar with this synthesis technology. Overall, the method’s reliability, robustness, and broad application base reinforce its dominant market position.
The liquid/enzymatic phase synthesis segment is expected to register the fastest growth during forecast period, propelled by its potential in enzymatic DNA/RNA synthesis, greener production methods, and emerging applications in synthetic biology. Advancements in enzymatic methods allow faster, environmentally friendly, and cost-effective synthesis. This method is particularly attractive for startups and research labs exploring innovative therapeutics and diagnostics. Liquid-phase synthesis can produce sequences difficult for solid-phase methods. Adoption is rising due to increasing interest in automated enzymatic platforms. Growing awareness of sustainable laboratory practices also supports segment expansion.
On the basis of application, the India oligonucleotides synthesis market is segmented into diagnostics, therapeutics, research, agriculture, food, and others. The diagnostics segment dominated the market with around 40% revenue share in 2024, due to increasing use of oligonucleotides in molecular diagnostics, genetic testing, and infectious disease detection. Rising prevalence of genetic disorders and demand for rapid, accurate diagnostic tools drive the segment. Clinical labs, hospitals, and diagnostic centers are major consumers, leveraging oligos for assay development and validation. Adoption of PCR, qPCR, and NGS-based tests further strengthens market dominance. Regulatory support for molecular diagnostics in India also contributes to segment growth. Continuous innovation in assay design ensures sustained demand for diagnostic oligos.
The therapeutics segment is expected to witness the fastest growth during forecast period, driven by expanding applications in RNA-based therapeutics, antisense oligonucleotides, and gene therapy. Pharmaceutical companies are increasingly investing in oligonucleotide therapeutics development. Growth is supported by collaborations with academic institutions and research labs. Increasing incidence of chronic and genetic diseases creates a rising need for precision therapeutics. Rapid technological advancements in oligonucleotide modifications enhance efficacy and safety, driving adoption. Government initiatives supporting biotechnology R&D also accelerate market expansion.
On the basis of end user, the India oligonucleotides synthesis market is segmented into pharmaceutical & biotechnology companies, diagnostic centers, CROs, research & academic institutes, and forensic labs. The pharmaceutical & biotechnology companies segment dominated the market with the largest revenue share of 45% in 2024, due to high consumption of oligonucleotides for drug development, molecular diagnostics, and therapeutic research. The dominance is supported by strategic partnerships with academic institutions and contract service providers. Rising investment in gene-targeted therapies and precision medicine further boosts demand. The segment benefits from continuous adoption of high-throughput synthesis and custom oligo solutions. Large companies’ ability to place bulk orders ensures steady revenue contribution. The segment also benefits from access to international collaborations and technology transfer.
The research & academic institutes segment is expected to witness the fastest growth during forecast period, driven by increasing genomics and molecular biology research in India. Government funding for biotechnology and life sciences research is rising. Academic labs are adopting oligonucleotide synthesis for diverse applications such as gene function studies, biomarker discovery, and synthetic biology. Startups associated with universities are leveraging these services for innovative therapeutics and diagnostics. Increasing focus on personalized medicine and genetic studies accelerates adoption. Growing availability of automated synthesis and cost-effective solutions further supports segment expansion.
On the basis of distribution channel, the India oligonucleotides synthesis market is segmented into direct tender, retail sales, and others. The direct tender segment dominated the market in 2024, particularly for bulk purchases by pharmaceutical companies, biotech firms, and large research institutions, ensuring steady revenue streams. Direct contracts allow buyers to access custom synthesis services with bulk pricing and guaranteed delivery timelines. The segment benefits from established relationships between manufacturers and large end users. Repeat orders for reagents and custom oligos also strengthen revenue contribution. Bulk procurement ensures cost efficiency for buyers and stable demand for suppliers. The segment’s dominance is supported by the consistent growth of large-scale R&D and therapeutic development projects.
The retail sales segment is expected to witness the fastest growth during forecast period, as smaller research labs, startups, and educational institutions increasingly prefer flexible, on-demand ordering of reagents, consumables, and small-scale oligonucleotide batches. Online platforms and specialized distributors enhance accessibility and convenience. Smaller labs benefit from reduced upfront costs and fast delivery. Growth is fueled by the increasing number of academic programs and biotech incubators in India. Retail channels also enable access to international suppliers for specialized products. Flexibility and convenience make retail sales attractive for emerging users and pilot-scale research.
The India oligonucleotides synthesis industry is primarily led by well-established companies, including:
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