Global In-Vitro Toxicology Testing Market, By Product and Service (Consumables, Services, Assays, Equipments, and Software), Toxicology End Point and Test (ADME (Absorption, Distribution, Metabolism, & Excretion) Testing, Cytotoxicity Testing, Genotoxicity Testing, Dermal Toxicity Testing, Ocular Toxicity Testing, Organ Toxicity Testing, Skin Irritation, Corrosion, & Sensitization Testing, Phototoxicity Testing, and Other Toxicity Endpoints & Tests), Technology (Cell Culture Technologies, High-Throughput Technologies, Molecular Imaging, and Omics Technology), Method (Cellular Assays, Biochemical Assays, Ex-Vivo Models, and In Silico Models), Industry (Pharmaceutical & Biopharmaceutical Companies, Diagnostics, Food, Chemicals, Cosmetics & Household Products), Distribution Channel (Direct Tender, Retail Sales, and Others) - Industry Trends and Forecast to 2030.
In-Vitro Toxicology Testing Market Analysis and Size
The global in-vitro toxicology testing market is fragmented in nature, as it consists of many global players such as Thermo Fisher Scientific Inc. (U.S.), Labcorp Drug Development (U.S.), Merck KGaA (Germany), Charles River Laboratories (U.S.), and Lonza (Switzerland) among others. The presence of these companies produces competitive prices for in-vitro toxicology testing products across the region. Due to the presence of these players at regional and international levels, suppliers and manufacturers offer products with different specifications and characteristics in all budgets. The rising demand for in-vitro toxicology testing products globally drives market growth. Additionally, the rapidly growing pharmaceutical and medical industries are expected to drive the market growth.
Data Bridge Market Research analyzes that the global in-vitro toxicology testing market is expected to reach USD 27,952.36 million by 2030, at a CAGR of 12.3% during the forecast period. This market report also covers pricing analysis and technological advancements in depth.
|
Report Metric
|
Details
|
|
Forecast Period
|
2023 to 2030
|
|
Base Year
|
2022
|
|
Historic Years
|
2021 (Customizable to 2015 - 2020)
|
|
Quantitative Units
|
Revenue in USD Million, Volumes in Units, and Pricing in USD
|
|
Segments Covered
|
By Product and Service (Consumables, Services, Assays, Equipments, and Software), Toxicology End Point and Test (ADME (Absorption, Distribution, Metabolism, & Excretion) Testing, Cytotoxicity Testing, Genotoxicity Testing, Dermal Toxicity Testing, Ocular Toxicity Testing, Organ Toxicity Testing, Skin Irritation, Corrosion, & Sensitization Testing, Phototoxicity Testing, and Other Toxicity Endpoints & Tests), Technology (Cell Culture, High-Throughput Technologies, Molecular Imaging, and Omics Technology), Method (Cellular Assays, Biochemical Assays, Ex-Vivo Models, and In Silico Models), Industry (Pharmaceutical & Biopharmaceutical Companies, Diagnostics, Food, Chemicals, Cosmetics & Household Products), Distribution Channel (Direct Tender, Retail Sales, and Others)
|
|
Countries Covered
|
U.S., Canada, Mexico, Germany, France, U.K., Italy, Spain, Netherlands, Russia, Switzerland, Turkey, Belgium, Rest of Europe, China, Japan, India, South Korea, Australia, Singapore, Thailand, Malaysia, Indonesia, Philippines, Rest of Asia-Pacific, Brazil, Argentina, Rest of South America, South Africa, Saudi Arabia, U.A.E., Egypt, Israel, and Rest of Middle East and Africa
|
|
Market Players Covered
|
Thermo Fisher Scientific Inc., Labcorp Drug Development, Merck KGaA, Charles River Laboratories, Lonza, Bio-Rad Laboratories, Inc., Catalent, Inc, SGS Société Générale de Surveillance SA, QIAGEN, Intertek Group plc., Eurofins Scientific, Promega Corporation, Aragen Life Sciences Ltd., Cyprotex Plc., Shanghai Medicilon Inc., Creative Biolabs, BioIVT, AAT Bioquest, Inc., Gentronix, IONTOX, InSphero, MB Research Laboratories, Creative Bioarray, and Preferred Cell Systems
|
Market Definition
In-vitro toxicology testing involves testing chemicals, drugs, and other substances to assess their potential toxicity using in-vitro (non-animal) testing methods. In-vitro toxicology testing involves using cells, tissues, or cellular components outside their natural environment to evaluate substances' safety and potential hazards. The market encompasses a wide range of in-vitro tests and assays that assess various aspects of toxicity, including but not limited to cytotoxicity, genotoxicity, carcinogenicity, organ toxicity, reproductive toxicity, and environmental toxicity. These tests are conducted on cell cultures, tissue models, or other in-vitro systems to mimic the response of biological systems to potential toxicants.
Global In-Vitro Toxicology Testing Market Dynamics
This section deals with understanding the market drivers, advantages, opportunities, restraints, and challenges. All of this is discussed in detail below:
DRIVERS
Increasing demand for toxicology testing products
The main activity of the pharmaceutical industry is quality management. Drugs must be sold as formulations that are sterile, therapeutically active, reliable, and predictable in their performance. New and improved medicinal agents are being developed at an accelerated speed. At the same time, more exact and sophisticated analytical methods are being developed for their evaluation. The Food and Drug Administration has issued several guidance documents for industry, such as safety testing of drug metabolites, in-vitro metabolism and transporter-mediated drug-drug interaction studies, and clinical drug interactions studies.
There is a need for sterile medical products for patient safety, along with safeguarding pharmaceutical and medical device companies from a product recall, further escalating the market demand. Therefore, increasing demand for toxicology testing products in the pharmaceutical and biotechnology industry drives the growth of the market.
Rapidly growing pharmaceutical and medical device industry
Many revolutionary trends and advances have been witnessed by the pharmaceutical and medical device industries, dramatically improving the medicines available to patients globally. It was possible to witness the effect of artificial intelligence and big data on the diagnosis and treatment of diseases.
Combined with their potential to remedy previously untreatable diseases, biopharmaceutical drugs' effectiveness, and protection help pharmaceutical companies succeed. An opportunity for sustained healthy growth supports the existing biologics-development pipeline. Since 1995, the number of biotech patents applied annually has increased by 25%. More than 1,500 biomolecules are presently undergoing clinical trials, and the biologics success rate has so far been more than double that of small-molecule drugs, with 13% of biopharmaceuticals entering the phase I testing phase going on to launch.
The prosperity and growth of these industries proportionally increase the demand for toxicity testing for the quality control of the products developed by them. Therefore, the rapidly growing pharmaceutical and medical device industries act as a driver for the growth of the market.
OPPORTUNITY
Growing adoption of quality check products to prevent product recalls
Medical devices, drugs, and biologics are increasingly important in today's healthcare delivery. However, ongoing quality concerns with drugs and related recalls raise possible health hazards to the use these drugs on patients. One of the major reasons for product recall in pharmaceutical companies is the toxicity profile of their drugs and other products, which could pose serious health complications among the patients who consume them.
In-process controls to track the existence of toxicity must include the aseptic production of compounded products. Therefore, effective and efficient monitoring for toxicity is important in the pharmaceutical and biomedical industries. All injectable or implantable products labeled as pyrogen-free or sterile must undergo toxicology testing before release. This avoids toxicity in patients and makes it easy to comply with regulatory and cGMP guidelines. Hence, the growing adoption of quality check products to prevent product recalls acts as an opportunity for market growth.
RESTRAINT / CHALLENGE
High cost associated with in-vitro toxicology testing and products
Automated toxicity testing systems are equipped with the latest technology and advanced features. They have wide functionalities and features. The automated AST gives efficient and accurate detection of toxicity. However, the high cost of these devices is likely to impact the market.
Thus, the advancement comprises of automated antimicrobial susceptibility testing (AST), Microdilution, rapid automated instrument methods, MIC strip tests, genotypic methods, disk diffusion method, e-tests, and POCT-compatible technologies, all these advanced features make the device costly. This may act as a restraining factor for the in-vitro toxicology testing market.
Recent Development
- In June 2023, Lonza, a global manufacturing partner to the pharmaceutical, biotech, and nutraceutical markets, announced it had acquired Synaffix B.V. (Synaffix), a biotechnology company focused on commercializing its clinical-stage technology platform for developing ADCs. This will help the company to expand their global presence
- In October 2022, Thermo Fisher Scientific Inc. announced that it will expand its laboratory operations in Highland Heights, Kentucky, helping customers deliver life-changing medicines to patients. The current facility, which includes central lab and biomarker operations, provides biopharma customers with high-quality laboratory services to accelerate drug development. This helped the company to expand its clinical diagnostics business across various regions in the world and helped to increase its global presence in the market
Global In-Vitro Toxicology Testing Market Scope
The global in-vitro toxicology testing market is segmented into six notable segments: product and service, toxicology end point and test, technology, method, industry, and distribution channel. The growth amongst these segments will help you analyze meager growth segments in the industries and provide the users with a valuable market overview and insights to help them make strategic decisions for identifying core market applications.
Product and Service
- Consumables
- Services
- Assay
- Equipments
- Software
Based on product and service, the global in-vitro toxicology testing market is segmented into consumables, services, assays, equipments, and software.
Toxicology End Point and Test
- ADME (Absorption, Distribution, Metabolism, & Excretion) Testing
- Cytotoxicity Testing
- Genotoxicity Testing
- Dermal Toxicity Testing
- Ocular Toxicity Testing
- Organ Toxicity Testing
- Skin Irritation, Corrosion, & Sensitization Testing
- Phototoxicity Testing, and Other Toxicity Endpoints & Test
Based on toxicology end point and test, the market is segmented into ADME (absorption, distribution, metabolism, & excretion) testing, cytotoxicity testing, genotoxicity testing, dermal toxicity testing, ocular toxicity testing, organ toxicity testing, skin irritation, corrosion, & sensitization testing, phototoxicity testing, and other toxicity endpoints & tests.
Technology
- Cell Culture Technologies
- High-Throughput Technologies
- Molecular Imaging
- OMICS Technology
Based on technology, the market is segmented into cell culture technologies, high-throughput technologies, molecular imaging, and OMICS technology.
Method
- Cellular Assays
- Biochemical Assays
- Ex-Vivo Models
- In Silico Models
Based on method the market is segmented into cellular assays, biochemical assays, ex-vivo models, and in silico models.
Industry
- Pharmaceutical & Biopharmaceutical Companies
- Diagnostics
- Food
- Chemicals
- Cosmetics & Household Products
Based on industry the market is segmented into pharmaceutical & biopharmaceutical companies, diagnostics, food, chemicals, cosmetics & household products.
Distribution Channel
- Direct Tender
- Retail Sales
- Others
Based on distribution channel, the market is segmented into direct tender, retail sales, and others.
Global In-Vitro Toxicology Testing Market Regional Analysis/Insights
The global in-vitro toxicology testing market is analyzed. As referenced above, market size insights and trends are provided by country, product and service, toxicology end point and test, technology, method, industry and distribution channel.
The countries covered in this market report are U.S., Canada, Mexico, Germany, France, U.K., Italy, Spain, Netherlands, Russia, Switzerland, Turkey, Belgium, rest of Europe, China, Japan, India, South Korea, Australia, Singapore, Thailand, Malaysia, Indonesia, Philippines, rest of Asia-Pacific, Brazil, Argentina, rest of South America, South Africa, Saudi Arabia, U.A.E., Egypt, Israel, and rest of Middle East and Africa.
North America is expected to dominate due to rising demand for toxicology testing, and technological advancements are anticipated to fuel the market growth during the forecast period in this region. The U.S. is expected to dominate North America due to rising demand for in-vitro toxicology testing products. China is expected to dominate Asia-Pacific as the strategic initiatives by the key market players are expanding significantly. Germany is expected to dominate Europe due to the rapidly growing pharmaceutical and medical industries.
The country section of the report also provides individual market-impacting factors and changes in market regulation that impact the current and future trends of the market. Data points like downstream and upstream value chain analysis, technical trends, Porter's five forces analysis, and case studies are some pointers used to forecast the market scenario for individual countries. Also, the presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, the impact of domestic tariffs, and trade routes are considered while providing forecast analysis of the country data.
Competitive Landscape and Global In-Vitro Toxicology Testing Market Share Analysis
The global in-vitro toxicology testing market competitive landscape provides details of the competitor. Details include company overview, financials, revenue generated, market potential, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, and application dominance. The above data points provided are only related to the companies' focus related to the market.
Some of the major market players operating in the global in-vitro toxicology testing market are Thermo Fisher Scientific Inc.(U.S.), Labcorp Drug Development (U.S.), Merck KGaA (Germany), Charles River Laboratories (U.S.), Lonza (Switzerland), Bio-Rad Laboratories, Inc. (U.S.), Catalent, Inc (U.S.), SGS Société Générale de Surveillance SA (Switzerland), QIAGEN (Germany), Intertek Group plc. (UK), Eurofins Scientific (Luxembourg), Promega Corporation (U.S.), Aragen Life Sciences Ltd. (India), Cyprotex Plc. (UK), Shanghai Medicilon Inc. (China), Creative Biolabs (U.S.), BioIVT (U.S.), AAT Bioquest, Inc. (U.S.), Gentronix (UK), IONTOX (U.S.), InSphero (U.S.), MB Research Laboratories (U.S.), Creative Bioarray (U.S.), and Preferred Cell Systems (U.S.) among others.
SKU-